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Penn researchers develop low-cost genetic test for Zika virus

University of Pennsylvania engineers have developed a rapid, low-cost genetic test for the Zika virus.

6 Jul 2016

Scientists discover new genetic variations linked to increased myeloma risk

Researchers have identified eight new genetic variations in the human genome that could be linked to an increased risk of developing myeloma. The findings provide additional evidence and build on existing research that suggests myeloma can run in families.

5 Jul 2016

Tiny viruses speed-up evolution of bacteria causing infections in cystic fibrosis patients

SCIENTISTS in the UK have found new evidence that tiny viruses called bacteriophages turbo-charge the evolution of bacteria that cause lung infections in Cystic Fibrosis patients.

5 Jul 2016

Novel technique could help discover genes linked to complex traits in any animal model

Mice are one of the most commonly used laboratory organisms, widely used to study everything from autism to infectious diseases. Yet genomic studies in mice have lagged behind those in humans.

4 Jul 2016

Researchers identify non-coding RNA NEAT1 as potential drug target to combat cancer

A team of researchers led by professor Jean-Christophe Marine has identified NEAT1, a non-coding RNA, as a potential therapeutic target in the fight against cancer.

4 Jul 2016

Recommendations for integrating genomic results into clinical practice

A quiet transformation has been brewing in medicine, as large-scale DNA results become increasingly available to patients and healthcare providers.

1 Jul 2016

Kataegis linked to better prognosis for breast cancer patients

Kataegis is a recently discovered phenomenon in which multiple mutations cluster in a few hotspots in a genome. The anomaly was previously found in some cancers, but it has been unclear what role kataegis plays in tumor development and patient outcomes.

1 Jul 2016

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

“IDPs” is now a widely used acronym that stands for “intrinsically disordered proteins.” It is the term generally used by the scientific community to refer to a wide variety of proteins that do not have a stable 3D structure and are instead characterized by a high extent of local mobility, disorder and many conformers that are accessible at room temperature.

From Bruker BioSpin Group 30 Jun 2016

Researchers determine how Ki-67 protein disperses chromosomes in dividing cells

Billions of your cells divide every day. Cell division fuels growth and also replaces short-lived cells in some organs, like your skin, blood, and gut.

30 Jun 2016

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors.

30 Jun 2016

New AAV 3.0 program to create next-generation viral vectors for better treatment of inherited diseases

The Perelman School of Medicine at the University of Pennsylvania has launched a new program, called AAV 3.0, to create new viral vectors to find quicker and better treatments for an array of diseases. James M. Wilson, MD, PhD, a professor of Medicine and director of the Orphan Disease Center, will lead an interdisciplinary team of over 30 scientists to create this new technology platform with support provided by the University of Pennsylvania Health System.

30 Jun 2016

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Viruses must avoid a host's immune system to establish successful infections—and scientists have discovered another tool that viruses use to frustrate host defenses.

30 Jun 2016

Study links alpha-defensin genes to IgA nephropathy risk

A gene which forms part of our body's first line of defence against infection may be associated with an increased risk with a type of kidney disease, research involving academics at The University of Nottingham has discovered.

30 Jun 2016

Researchers develop new computational method to track colorectal cancer progression

Team of researchers elaborated a computational method to track the progress of the colorectal cancer. It is a scientific advance that can bring new perspectives to discover the factors that push this pathology and the selection of efficient therapies.

29 Jun 2016

Genome News and Research

Penn researchers develop low-cost genetic test for Zika virus

Scientists discover new genetic variations linked to increased myeloma risk

Tiny viruses speed-up evolution of bacteria causing infections in cystic fibrosis patients

Novel technique could help discover genes linked to complex traits in any animal model

Researchers identify non-coding RNA NEAT1 as potential drug target to combat cancer

Recommendations for integrating genomic results into clinical practice

Kataegis linked to better prognosis for breast cancer patients

Using NMR to investigate intrinsically disordered proteins: an interview with Dr Isabella Felli

Researchers determine how Ki-67 protein disperses chromosomes in dividing cells

Study focuses on critical proteins involved in ovarian cancer biology

New AAV 3.0 program to create next-generation viral vectors for better treatment of inherited diseases

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Study links alpha-defensin genes to IgA nephropathy risk

Researchers develop new computational method to track colorectal cancer progression

Researchers identify set of genes that play vital role in early human development

Researchers devise method to identify functional contribution of SIRT6

Study demonstrates epigenetic link between environment and pubertal onset in humans

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Researchers identify exact origin of 2009 swine H1N1 flu pandemic

Virus-like elements within human genome linked to development of lupus and Sjogren's syndrome

Genetics & Genomics - Second Edition eBook

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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