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Study indicates that RNA translation is dictated by translational hotspots

Protein synthesis in the extensions of nerve cells, called dendrites, underlies long-term memory formation in the brain, among other functions. "Thousands of messenger RNAs reside in dendrites, yet the dynamics of how multiple dendrite messenger RNAs translate into their final proteins remain elusive," says James Eberwine, PhD, professor of Pharmacology, Perelman School of Medicine at the University of Pennsylvania, and co-director of the Penn Genome Frontiers Institute.

27 Sep 2013

Genes in mitochondria shape each person's risk for heart disease and diabetes

Genes in mitochondria, the "powerhouses" that turn sugar into energy in human cells, shape each person's risk for heart disease and diabetes, according to a study published recently by researchers at the University of Alabama at Birmingham in the Biochemical Journal.

27 Sep 2013

New public resource to help researchers explore data from the NIH human microbiome project

The National Institutes of Health (NIH) has launched the first phase of the Microbiome Cloud Project (MCP), a collaboration with Amazon Web Services that aims to improve access to and analysis of data from the Human Microbiome Project (HMP).

27 Sep 2013

Mayo Clinic experts to discuss risk factors, screening and treatments for breast cancer

October is National Breast Cancer Awareness Month, and Mayo Clinic breast cancer experts are available to discuss risk factors, screening and treatments.

27 Sep 2013

Scientists study genetic factors involved in complex diseases

Although heavily studied, the specific genetic causes of "complex diseases," a category of disorders which includes autism, diabetes and heart disease, are largely unknown due to byzantine genetic and environmental interactions.

27 Sep 2013

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

The mood changes of a 'Jekyll-and-Hyde' protein, which sometimes boosts tumour cell growth and at other times suppresses it, have been explained in a new study led by Oxford University researchers.

27 Sep 2013

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

Three grants totaling more than $25 million over four years will help three research groups to develop authoritative information on the millions of genomic variants relevant to human disease and the hundreds that are expected to be useful for clinical practice. The awards are from the National Institutes of Health.

26 Sep 2013

Global Genomics Group Enlists Illumina For Cardiovascular Disease Study

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From Illumina, Inc. 25 Sep 2013

$Researchers show link between FTO gene and hip fracture in women$

Researchers show link between FTO gene and hip fracture in women

Australian researchers have demonstrated a strong association between the FTO (fat and obesity) gene and hip fracture in women. While the gene is already well known to affect diabetes and obesity, this is the first study to show that its high-risk variant can increase the risk of hip fracture by as much as 82%.

25 Sep 2013

miR-31 in primary tumor cells predicts lymph node metastasis in NSCLC patients

Determining whether a patient's lung cancer has spread to nearby lymph nodes is critical for identifying the most effective therapy, but it usually requires surgery. A new study suggests, however, that measuring levels of a particular molecule in a sample of tumor tissue might accurately answer the question.

25 Sep 2013

Inherited human herpesvirus 6 affects telomere stability and reactivates

Up to half a million people in Britain today may not know it, but in their genetic material they carry a particular form of herpesvirus 6 inherited from a parent.

21 Sep 2013

Research team sequences genome of Pyronema confluens

The genomes of more than 250 fungi have been sequenced. Among the basal filamentous ascomycetes - a group of ascomycetes that includes e.g. truffles and morels - only one representative has been analysed so far: the truffle Tuber melanosporum.

21 Sep 2013

Genetics in Medicine's October 2013 issue details solutions for integrating genomic data into EHR

Genetic tests can now tell us whether we are at increased risk of various cancers, heart or kidney disease, asthma and a number of other conditions.

20 Sep 2013

Researchers discover new mechanism involving p53 to fight against aggressive cancers

Researchers at A*STAR's Singapore Immunology Network (SIgN) have discovered a new mechanism involving p53, the famous tumour suppressor, to fight against aggressive cancers.

20 Sep 2013

Human breast tumors transplant could be valuable tools in search for better treatments

Breast cancer that spreads to other organs is extremely difficult to treat. Doctors can buy patients time, but a cure remains elusive. Now, researchers at Washington University School of Medicine in St. Louis have shown that human breast tumors transplanted into mice are excellent models of metastatic cancer and could be valuable tools in the search for better treatments.

20 Sep 2013

NY Genome Center Marks Its Formal Launch

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19 Sep 2013

Study sheds new light on the dark matter of genome

Using technology he helped develop, Vanderbilt University scientist Bryan Venters, Ph.D., has shed new light on the "dark matter" of the genome and has begun to explore a possible new approach to treating cancer.

19 Sep 2013

Johns Hopkins establishes center to study ELSI of applying genomics to infectious disease treatment

The National Human Genome Research Institute has selected the Johns Hopkins Berman Institute of Bioethics to establish a "Center of Excellence" to study the ethical, legal and social implications of genomic research.

19 Sep 2013

Sequenom announces Certified Service Provider program for technical certification

Sequenom, Inc., a life sciences company providing innovative diagnostic testing and genetic analysis solutions, today announced a Certified Service Provider (CSP) program for the technical certification of selected laboratories offering research services using the Sequenom research-use-only MassARRAY System.

18 Sep 2013

Mayo Clinic to host annual Individualizing Medicine Conference from Sept. 30 to Oct. 2

From Promise to Practice is the title and the main message of the second annual Individualizing Medicine Conference at Mayo Clinic, Sept. 30-Oct. 2. Physicians from more than 40 states and several countries will be arriving in Minnesota to hear and learn about the latest developments and research in genomic research and how to move these discoveries into the medical practice.

18 Sep 2013

Genome News and Research

Study indicates that RNA translation is dictated by translational hotspots

Genes in mitochondria shape each person's risk for heart disease and diabetes

New public resource to help researchers explore data from the NIH human microbiome project

Mayo Clinic experts to discuss risk factors, screening and treatments for breast cancer

Scientists study genetic factors involved in complex diseases

'Jekyll-and-Hyde' protein could be potent target for developing new cancer drugs

Three research groups awarded NIH grants to develop framework for evaluating genetic variants

Global Genomics Group Enlists Illumina For Cardiovascular Disease Study

Researchers show link between FTO gene and hip fracture in women

miR-31 in primary tumor cells predicts lymph node metastasis in NSCLC patients

Inherited human herpesvirus 6 affects telomere stability and reactivates

Research team sequences genome of Pyronema confluens

Genetics in Medicine's October 2013 issue details solutions for integrating genomic data into EHR

Researchers discover new mechanism involving p53 to fight against aggressive cancers

Human breast tumors transplant could be valuable tools in search for better treatments

NY Genome Center Marks Its Formal Launch

Study sheds new light on the dark matter of genome

Johns Hopkins establishes center to study ELSI of applying genomics to infectious disease treatment

Sequenom announces Certified Service Provider program for technical certification

Mayo Clinic to host annual Individualizing Medicine Conference from Sept. 30 to Oct. 2

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