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Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Researchers demonstrated the sarbecovirus open reading frame 7a (ORF7a)-induced hindrance of the antigen presentation by the major histocompatibility complex class I (MHC-I) in hosts.

30 May 2022

Researchers identify a human monoclonal antibody that could broadly neutralize several variants of SARS-CoV-2, SARS-CoV, and other coronaviruses

Researchers identified 10-40, a human monoclonal antibody with potent neutralizing activity against SARS-CoV, SARS-CoV-2, and related sarbecoviruses.

30 May 2022

Exploring virological profiles of recently emerged SARS-CoV-2 Omicron variants

Researchers explored the virological profiles of novel SARS-CoV-2 Omicron variants.

30 May 2022

Method for predicting neutralization and protection based on variant-specific antibody measurements to SARS-CoV-2 antigens

Researchers reported a method to predict neutralization and protection against SARS-CoV-2 antigens.

30 May 2022

Direct comparison of immune memory responses to four COVID-19 vaccines

Researchers evaluated host immune responses to four COVID-19 vaccines representing three different vaccine technology platforms, focusing on immune memory responses.

30 May 2022

Hemodialysis patients obtain a robust humoral response from a third dose of the BNT162b2 vaccine, study finds

Researchers assessed the humoral immune responses generated by the third Pfizer-BioNTech BNT162b2 mRNA vaccination against SARS-CoV-2 among hemodialysis patients.

30 May 2022

Interactive web portal details the extent of splicing events in noncoding sequences

An online tool reveals the extent of gene-restructuring events in noncoding sequences.

30 May 2022

Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome

A new study utilizes multisystem imaging, along with biomarker analysis, to better understand the pathogenesis of COVID-19.

30 May 2022

Study finds TGF-β2 associated with asymptomatic mild SARS-CoV-2 infection during pregnancy

A new study investigated the clinical and obstetric outcomes after SARS-CoV-2 infection in two groups of pregnant women, along with their association with the immunological parameters.

28 May 2022

Oil-based gels could make it easier for children to swallow medicines

For most children and even some adults, swallowing pills or tablets is difficult. To make it easier to give those medicines, researchers at MIT and Brigham and Women's Hospital have created a drug-delivering gel that is much easier to swallow and could be used to administer a variety of different kinds of drugs.

27 May 2022

Gene linked to severe learning disabilities plays a key role in cells' response to environmental stress

A gene that has been associated with severe learning disabilities in humans has been found to also play a vital role in cells' response to environmental stress, according to a Duke University study appearing May 24 in the journal Cell Reports.

27 May 2022

T cells can die without rest and maintenance, scientists say

T cells, biology textbooks teach us, are the soldiers of the immune system, constantly on the ready to respond to a variety of threats, from viruses to tumors.

27 May 2022

Pediatric patients with prior COVID-19 or MIS-C are not protected against Omicron

Research drawing on the national Overcoming COVID-19 study, led by Boston Children's Hospital, and the hospital's own Taking On COVID-19 Together Group provides evidence that children who previously had COVID-19 (or the inflammatory condition MIS-C) are not protected against the newer Omicron variant.

27 May 2022

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Biological arms races are commonplace in nature. Cheetahs, for example, have evolved a sleek body form that lends itself to rapid running, enabling them to feast upon similarly speedy gazelles, the fastest of which may evade predation.

27 May 2022

Understanding transposons provides a new starting point to generate more powerful gene editing tools

CRISPR has ushered in the era of genomic medicine. A line of powerful tools has been developed from the popular CRISPR-Cas9 to cure genetic diseases.

27 May 2022

Exploring antigenic traits of SARS-CoV-2 Omicron BA.5 and BA.4 subvariants

Scientists analyzed the antigenic characteristics of the severe acute respiratory syndrome coronavirus 2 Omicron BA.5 and BA.4 sublineages.

27 May 2022

Nexus Medical Labs receives FDA Emergency Use Authorization for SARS-CoV-2 test using the RHINOstic™ Automated Nasal Swab from Rhinostics

Rhinostics Inc. and Nexus Medical Labs recently received Emergency Use Authorization (EUA) from the US Food and Drug Administration (FDA) for a molecular SARS-CoV-2 test enabling unsupervised self-collection.

From Rhinostics 27 May 2022

New approach could treat brain tumors and also prevent or delay recurrences

Scientists at the University of Michigan Rogel Cancer Center were optimistic when they identified a small molecule that blocked a key pathway in brain tumors.

27 May 2022

Study evaluates diagnostic performance of two blood-based biomarkers specific to Alzheimer's disease

A simple blood test to diagnose Alzheimer's disease, perhaps even years before symptoms appear, is an exciting possibility, but a new study shows that much more research is needed before these blood tests are routinely used in the clinical diagnostic setting.

26 May 2022

FDA grants Breakthrough Device designation for Emily's Care Nourish Test System

Lactation Lab, which offers the most scientifically advanced breast milk testing available, has announced today that the U.S. Food and Drug Administration, has granted the company Breakthrough Device designation for its latest device Emily's Care Nourish Test System that tests and provides a nutritional analysis of breast milk.

26 May 2022

Protein C News and Research

Sarbecovirus open reading frame 7a suppresses major histocompatibility complex-I antigen presentation

Researchers identify a human monoclonal antibody that could broadly neutralize several variants of SARS-CoV-2, SARS-CoV, and other coronaviruses

Exploring virological profiles of recently emerged SARS-CoV-2 Omicron variants

Method for predicting neutralization and protection based on variant-specific antibody measurements to SARS-CoV-2 antigens

Direct comparison of immune memory responses to four COVID-19 vaccines

Hemodialysis patients obtain a robust humoral response from a third dose of the BNT162b2 vaccine, study finds

Interactive web portal details the extent of splicing events in noncoding sequences

Scientists determine trajectory and pathophysiology of post-COVID-19 syndrome

Study finds TGF-β2 associated with asymptomatic mild SARS-CoV-2 infection during pregnancy

Oil-based gels could make it easier for children to swallow medicines

Gene linked to severe learning disabilities plays a key role in cells' response to environmental stress

T cells can die without rest and maintenance, scientists say

Pediatric patients with prior COVID-19 or MIS-C are not protected against Omicron

Penn biologists show evidence of a two-sided genomic arms race involving repetitive DNA

Understanding transposons provides a new starting point to generate more powerful gene editing tools

Exploring antigenic traits of SARS-CoV-2 Omicron BA.5 and BA.4 subvariants

Nexus Medical Labs receives FDA Emergency Use Authorization for SARS-CoV-2 test using the RHINOstic™ Automated Nasal Swab from Rhinostics

New approach could treat brain tumors and also prevent or delay recurrences

Study evaluates diagnostic performance of two blood-based biomarkers specific to Alzheimer's disease

FDA grants Breakthrough Device designation for Emily's Care Nourish Test System

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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