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New biomarker for early cancer detection? Research reveals that 'microRNA' may fit the bill

Scientists at Fred Hutchinson Cancer Research Center have discovered that microRNAs - molecular workhorses that regulate gene expression - are released by cancer cells and circulate in the blood, which gives them the potential to become a new class of biomarkers to detect cancer at its earliest stages. Muneesh Tewari, M.D., Ph.D., and colleagues describe their findings in the July 28 issue of the Proceedings of the National Academy of Sciences.

29 Jul 2008

How anti-depressants and cocaine interact with brain

In a first, scientists from Weill Cornell Medical College and Columbia University Medical Center have described the specifics of how brain cells process antidepressant drugs, cocaine and amphetamines. These novel findings could prove useful in the development of more targeted medication therapies for a host of psychiatric diseases, most notably in the area of addiction.

28 Jul 2008

Lung inflammation from influenza and other infections could be turned off following new discovery

A new discovery could lead to treatments which turn off the inflammation in the lungs caused by influenza and other infections, according to a study published in the journal Nature Immunology.

27 Jul 2008

Link between small birth size and changes to the CV system that predispose to disease in later life

Researchers have found the first evidence that smaller size at birth is associated with specific alterations in the functioning of the heart and circulation in children and that these changes differ between boys and girls.

22 Jul 2008

International goals to reduce malaria burdens not likely to be achieved

For malaria control goals to be achieved, we must in the future tie funding commitments closer to level of need, says new research by Bob Snow and colleagues from the Kenyan Medical Research Institute-Oxford University-Wellcome Trust Collaborative Programme.

22 Jul 2008

Discovery of new anatomical path through which the brain and spleen communicate

In a major step in understanding how the nervous system and the immune system interact, scientists at The Feinstein Institute for Medical Research have identified a new anatomical path through which the brain and the spleen communicate.

21 Jul 2008

Study shows promising results in deep brain stimulation for treatment-resistant depression

New data from a study of patients with treatment-resistant depression who underwent deep brain stimulation (DBS) in the subcallosal cingulate region (SCG or Cg25) of the brain shows that this intervention is generally safe and provides significant improvement in patients as early as one month after treatment. The patients also experienced continued and sustained improvement over time.

21 Jul 2008

CUPID cannabinoid MS study reaches milestone

The CUPID (Cannabinoid Use in Progressive Inflammatory brain Disease) study at the Peninsula Medical School in Plymouth has reached an important milestone with the news that the full cohort of 493 people with multiple sclerosis (MS) has been recruited to the study.

21 Jul 2008

Obsessive compulsive disorder linked to activity in lateral orbitofrontal cortex

Cambridge researchers have discovered that measuring activity in a region of the brain could help to identify people at risk of developing obsessive compulsive disorder (OCD).

19 Jul 2008

Functional human blood vessels grown in mice using cells from adult human donors

For the first time, researchers have successfully grown functional human blood vessels in mice using cells from adult human donors - an important step in developing clinical strategies to grow tissue, researchers report in Circulation Research: Journal of the American Heart Association.

19 Jul 2008

A search for the best prostate cancer treatment

A new Cancer Research UK clinical trial has been launched to investigate the best treatment options for men who have had surgery for early stage prostate cancer.

18 Jul 2008

Physical activity programs for persons with dementia

Physical activity is a good thing for nearly everybody and clearly boosts alertness and a sense of well-being. So can we use it as a treatment for elderly patients with dementia? That's a good question, but existing research doesn't provide an answer, according to a new Cochrane Library review.

17 Jul 2008

New British consortium to tackle healthcare associated infections

Just over 8% of all hospital inpatients in England develop a healthcare associated infection, with this figure rising to 23% in intensive care units. Preventing and controlling the transmission of infection is a key priority for those involved in healthcare.

16 Jul 2008

Old bones could hold the key to tuberculosis

Close to 50 boxes of human and animal bones excavated in Jericho and held in the University of Sydney's Nicholson Museum could hold the key for an international medical team to unlock the causes of tuberculosis.

16 Jul 2008

Allergy to road traffic

Allergic diseases appear more often in children who grow up near busy roads. This is the result of a study of several thousand children, now published in the American Journal of Respiratory and Critical Care Medicine.

14 Jul 2008

Scientists reveal potential new target for anti-malarial drugs

Scientists funded by the Wellcome Trust have identified a key mechanism that enables malaria-infected red blood cells to stick to the walls of blood vessels and avoid being destroyed by the body's immune system. The research, published today in the journal Cell, highlights an important potential new target for anti-malarial drugs.

10 Jul 2008

New understanding of how malaria parasite survives in and totally changes red blood cells

A new study-done on a scale an order of magnitude greater than anything previously attempted in the field of malaria-has uncovered an arsenal of proteins produced by the malaria parasite that allows it to hijack and remodel human red blood cells, leaving the oxygen-carrying cells stiff and sticky.

8 Jul 2008

Novel ways to boost vaccination or natural defenses

Our bodies rely on the production of potent, or 'high affinity', antibodies to fight infection. The process is very complex, yet Sydney scientists have discovered that it hinges on a single molecule, a growth factor, without which it cannot function.

8 Jul 2008

AMDL granted FDA clearance to market blood test for colorectal cancer

AMDL has announced that the US Food and Drug Administration (FDA) has issued a letter of substantial equivalence to an existing predicate device and granted clearance to market the AMDL-ELISA DR-70(R) (FDP) as a safe and effective blood test for monitoring patients who have been previously diagnosed with colorectal cancer (CRC).

7 Jul 2008

Protein thought to promote cancer instead functions as a tumor suppressor

A protein previously thought to promote colorectal cancer instead suppresses the growth of human cancer cells in culture, researchers at UT Southwestern Medical Center have found.

7 Jul 2008

Medical Research News and Research

New biomarker for early cancer detection? Research reveals that 'microRNA' may fit the bill

How anti-depressants and cocaine interact with brain

Lung inflammation from influenza and other infections could be turned off following new discovery

Link between small birth size and changes to the CV system that predispose to disease in later life

International goals to reduce malaria burdens not likely to be achieved

Discovery of new anatomical path through which the brain and spleen communicate

Study shows promising results in deep brain stimulation for treatment-resistant depression

CUPID cannabinoid MS study reaches milestone

Obsessive compulsive disorder linked to activity in lateral orbitofrontal cortex

Functional human blood vessels grown in mice using cells from adult human donors

A search for the best prostate cancer treatment

Physical activity programs for persons with dementia

New British consortium to tackle healthcare associated infections

Old bones could hold the key to tuberculosis

Allergy to road traffic

Scientists reveal potential new target for anti-malarial drugs

New understanding of how malaria parasite survives in and totally changes red blood cells

Novel ways to boost vaccination or natural defenses

AMDL granted FDA clearance to market blood test for colorectal cancer

Protein thought to promote cancer instead functions as a tumor suppressor

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