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Specialized gene editing system paves way to eventual cure for HIV patients

A specialized gene editing system designed by scientists at the Lewis Katz School of Medicine at Temple University is paving the way to an eventual cure for patients infected with HIV, the virus that causes AIDS.

22 Mar 2016

Crash risk higher among truck drivers not adhering to sleep apnea treatment

Truck drivers who have obstructive sleep apnea and who do not attempt to adhere to a mandated treatment program have a fivefold increase in the risk of a severe crash, according to a new study co-authored by Virginia Tech Transportation Institute researchers and featured in the March 21 online edition of the journal Sleep.

22 Mar 2016

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

At least half of Parkinson's disease patients experience psychosis at some point during the course of their illness, and physicians commonly prescribe antipsychotic drugs, such as quetiapine, to treat the condition. However, a new study by researchers at the Perelman School of Medicine at the University of Pennsylvania, the University of Michigan Medical School, and the Philadelphia and Ann Arbor Veterans Affairs Medical Centers and suggests that these drugs may do significantly more harm in a subset of patients.

21 Mar 2016

KORs could be potential drug target for treatment of addiction, anxiety disorders

University of North Carolina researchers uncovered a cellular mechanism by which kappa opioid receptors (KOR) drive anxiety. These proteins inhibit the release of the neurotransmitter glutamate in a part of the brain that regulates emotion.

21 Mar 2016

Researchers develop conceptual model to help LGBTQ patients with multiple minority identities

Lesbian, gay, bisexual, transgender and queer (LGBTQ) patients who are also racial and ethnic minorities suffer significant health disparities, while facing more complicated challenges than white LGBTQ or racial and ethnic minority patients alone.

21 Mar 2016

Parents believe some online doctor reviews not trustworthy, reveals new national poll

For many, checking online reviews has become nearly routine for decisions on everything from cars to restaurants. But when it comes to choosing a doctor, the majority of parents aren't convinced online ratings are reliable - or even real, a new national poll shows.

21 Mar 2016

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

In an article published online ahead of print on Feb. 19, 2015 in the Journal of Biological Chemistry, investigators at the Medical University of South Carolina and the Ralph H. Johnson VA Medical Center report findings from in vitro and in vivo studies that elucidate the mechanisms underlying the impaired ciliogenesis and abnormal kidney development characteristic of polycystic kidney disease (PKD).

21 Mar 2016

Mutated gene GT198 has strong potential in early diagnosis of breast cancer

When mutated, a gene known for its ability to repair DNA, appears to instead cause breast cancer, scientists report.

21 Mar 2016

Trimeprazine improves β cell function, slows progression of diabetes

β cells in pancreatic islets are responsible for producing insulin, which is essential to regulate blood glucose homeostasis. In type 1 diabetes, pancreatic β cells are destroyed due to an autoimmune attack, whereas in type 2 diabetes, pancreatic β cells may have deficiencies in secreting insulin or insulin-responding tissues can become insulin resistant.

21 Mar 2016

Researchers reveal link between necrotizing enterocolitis and uropathogenic E. coli

Necrotizing enterocolitis is an intestinal disease that afflicts about one in 10 extremely premature infants and is fatal in nearly one-third of cases. The premature infant gut is believed to react to colonizing bacteria, causing damage to the intestinal walls and severe infection.

21 Mar 2016

Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

Physicians are prescribing more opioid painkillers than ever before to patients undergoing common surgeries, according to new research from the department of Anesthesiology and Critical Care at the Perelman School of Medicine at the University of Pennsylvania.

21 Mar 2016

Simple TB screening and isoniazid can be effective for HIV patients at risk for TB

The number one killer of HIV patients in resource-limited areas, including parts of Africa and India, is tuberculosis (TB), underscoring the need for optimal treatments and effective strategies to address this deadly co-infection. But TB is harder to detect in HIV-infected patients and diagnostic test results take time, so many healthcare providers prescribe multi-drug TB treatments as a precaution.

20 Mar 2016

Behavioral scientist shares insights about FDA's proposed rule on banning tanning bed use among minors

In late December 2015, the U.S. Food and Drug Administration proposed a number of new restrictions related to the use of tanning beds, including banning their use among individuals younger than 18 years.

19 Mar 2016

Innovative treatment may help prevent brain swelling, death in stroke patients

New research has provided more evidence that an innovative treatment strategy may help prevent brain swelling and death in stroke patients. J. Marc Simard, professor of neurosurgery at the University of Maryland School of Medicine, along with colleagues at Yale University and Massachusetts General Hospital, found that Cirara, an investigational drug, powerfully reduced brain swelling and death in patients who had suffered a type of large stroke called malignant infarction, which normally carries a high mortality rate.

19 Mar 2016

Manipulation of NAD could lead to potential therapy for acute kidney injury

Approximately one out of five hospitalized adults and one out of three hospitalized children worldwide experience acute kidney injury, the sudden loss of kidney function. Many different factors, including surgery, chemotherapy or shock, can lead to acute kidney injury, but exactly why the kidneys are so vulnerable to these and other stressors has not been well understood.

19 Mar 2016

Family-linked treatment may benefit children with cardiomyopathy-related chronic heart disease

A newly published national study by the Children's Hospital of Michigan and Wayne State University School of Medicine researchers shows that "parental impact and family functioning" become increasingly abnormal when children with cardiomyopathy-related chronic heart disease are more severely ill than children less affected by the disease.

18 Mar 2016

New scaffold technology could someday help treat Parkinson's disease, other brain-related conditions

Scientists at Rutgers and Stanford universities have created a new technology that could someday help treat Parkinson's disease and other devastating brain-related conditions that affect millions of people.

18 Mar 2016

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Research from Rutgers Cancer Institute of New Jersey examining difficult to treat cancer tumors through genomic profiling shows that tumors with alterations in a signaling pathway responsible for cell regulation may respond to targeted therapy regardless of where the tumor originated in the body.

18 Mar 2016

Harvard University launches iPhone research app to examine health and well-being football players

The Football Players Health Study at Harvard University--a series of studies that examine the health and well-being of former football players and aims to develop more effective diagnostic and therapeutic interventions--today launched TeamStudy, an iPhone research app built using ResearchKit, the open source software framework designed by Apple.

18 Mar 2016

New study reveals why certain cancer drugs not always effective in halting tumor growth

New cancer drugs allow doctors to tailor treatment based on the genetic profile of a patient's tumor. However, these drugs don't work at all in some patients, and they lose their effectiveness in others.

17 Mar 2016

Medical School News and Research

Specialized gene editing system paves way to eventual cure for HIV patients

Crash risk higher among truck drivers not adhering to sleep apnea treatment

Antipsychotic drugs may do significantly more harm to Parkinson's disease patients

KORs could be potential drug target for treatment of addiction, anxiety disorders

Researchers develop conceptual model to help LGBTQ patients with multiple minority identities

Parents believe some online doctor reviews not trustworthy, reveals new national poll

Researchers elucidate mechanisms underlying impaired ciliogenesis in PKD

Mutated gene GT198 has strong potential in early diagnosis of breast cancer

Trimeprazine improves β cell function, slows progression of diabetes

Researchers reveal link between necrotizing enterocolitis and uropathogenic E. coli

Penn study calls on physicians to avoid over-prescribing opioids for surgical patients

Simple TB screening and isoniazid can be effective for HIV patients at risk for TB

Behavioral scientist shares insights about FDA's proposed rule on banning tanning bed use among minors

Innovative treatment may help prevent brain swelling, death in stroke patients

Manipulation of NAD could lead to potential therapy for acute kidney injury

Family-linked treatment may benefit children with cardiomyopathy-related chronic heart disease

New scaffold technology could someday help treat Parkinson's disease, other brain-related conditions

Genomic profiling could help provide targeted therapies for difficult to treat cancer tumors

Harvard University launches iPhone research app to examine health and well-being football players

New study reveals why certain cancer drugs not always effective in halting tumor growth

Industry Focus eBook - Neurology/Neuroscience - 2nd edition eBook

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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