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Seattle-area health cooperative offers alternative health system model

Innovations in care by a Seattle-area cooperative and clinic are shaping debate about what health care reform around America should look like, The New York Times reports.

7 Jul 2009

Treatment blood pressure targets for hypertension

Aiming for lower than standard blood pressure targets offers no known clinical benefit, according to a Cochrane Review. In a systematic review of the evidence, researchers found that using antihypertensive drugs to reduce blood pressure below the 140/90 mm Hg standard was not associated with any reduction in death rates or serious morbidity.

7 Jul 2009

Combining two common medical tests provides new way to screen for serious kidney disease

The combination of two common medical tests can improve a doctor's ability to predict which patients will develop serious kidney disease, a research team led by the Norwegian University of Science and Technology (NTNU) reports in a recent issue of the Journal of the American Society of Nephrology.

7 Jul 2009

Identification of cholesterol regulating genes by targeted RNAi-screening

Scientists at the European Molecular Biology Laboratory (EMBL) and the University of Heidelberg, Germany, have come a step closer to understanding how cholesterol levels are regulated. In a study published today in the journal Cell Metabolism, the researchers identified 20 genes that are involved in this process. Besides giving scientists a better idea of where to look to uncover the mechanisms that ensure cholesterol balance is maintained, the discovery could lead to new treatments for cholesterol-related diseases.

7 Jul 2009

Chinese herbal medicine for endometriosis

Chinese herbal medicine (CHM) may relieve symptoms in the treatment of endometriosis. A systematic review by Cochrane Researchers found some evidence that women had comparable benefits following laparoscopic surgery and suffered fewer adverse effects if they were given Chinese herbs compared with conventional drug treatments.

7 Jul 2009

Johns Hopkins leads first 16-patient, multicenter "domino donor" kidney transplant

Surgical teams at The Johns Hopkins Hospital, Barnes-Jewish Hospital in St. Louis, INTEGRIS Baptist Medical Center in Oklahoma City and Henry Ford Hospital in Detroit successfully completed the first eight-way, multihospital, domino kidney transplant. The transplant involved eight donors - 3 men and 5 women along with eight organ recipients - 3 men and 5 women. "All Johns Hopkins patients are in good condition and are recovering as anticipated," according to Robert A. Montgomery, M.D., Ph.D., director of the Johns Hopkins Comprehensive Transplant Center.

7 Jul 2009

Artemisinin-based combination therapy for treating uncomplicated malaria

Current combination malaria therapies recommended by the World Health Organisation (WHO) provide adequate treatment for mild malaria, according to a Cochrane Systematic Review of the evidence. However, selected trials had high failure rates for some combinations and evidence for the effectiveness of anti-malarial therapies is lacking in some vulnerable groups.

7 Jul 2009

Erythropoietin improves learning and other higher brain functions

Healthy young mice treated with erythropoietin show lasting improved performance in learning and other higher brain functions. Researchers writing in the open access journal BMC Biology tested the cognitive effects of the growth factor, finding that it improved the sequential learning and memory components of a complex long-term cognitive task.

7 Jul 2009

U.S. military broad-based influenza monitoring system

The recent global swine flu outbreak has underscored the critical need for good surveillance and rapid access to epidemiological data. The US military, starting with early monitoring efforts in the 1970s, has developed a broad-based influenza monitoring system. In an article published in the September 2009 issue of the American Journal of Preventive Medicine, researchers describe this little-known national jewel that has repeatedly made notable contributions to global influenza control through close collaboration with CDC, the Food and Drug Administration (FDA), the WHO, and many other partners.

7 Jul 2009

New strategies to improve treatment and prevent heart failure in children

Structural cardiovascular abnormalities present at birth are the leading cause of heart failure in children. Nearly half a million children in the United States have structural heart problems ranging in severity from relatively simple issues, such as small holes between chambers of the heart, to very severe malformations, including complete absence of one or more chambers or valves.

7 Jul 2009

Senior breast cancer patients receive ‘chemo’ if treated in private practices

In a study to determine the non-medical factors that may be associated with the decision to treat nonmetastatic breast cancer, researchers at Columbia University Mailman School of Public Health evaluated the association between oncologist characteristics and the receipt of chemotherapy in elderly women with breast cancer and found that they were more likely to receive chemotherapy if treated by oncologists employed in a private practice.

7 Jul 2009

Researchers profile genes in acutely ill idiopathic pulmonary fibrosis patients

The first findings from a one-of-a-kind, patient-driven effort to provide lung tissue for research might help doctors predict when patients with idiopathic pulmonary fibrosis (IPF) are becoming dangerously ill and also could point the way to interventions that could sustain them until life-saving transplants can be performed.

7 Jul 2009

Research pinpoints antibodies that may prevent Alzheimer's

Antibodies to a wide range of substances that can aggregate to form plaques, such as those found in Alzheimer's patients, have been identified in the blood and cerebrospinal fluid of healthy people. Levels of these antibodies decline with age and, in Alzheimer's patients, with increasing progression of the disease.

6 Jul 2009

Amino acid commonly found in vegetable protein may lower blood pressure

Consuming an amino acid commonly found in vegetable protein may be associated with lower blood pressure, researchers report in Circulation: Journal of the American Heart Association.

6 Jul 2009

Future of organ transplantation - microscopic beads that create "designer " immune cells

The future of organ transplantation could include microscopic beads that create "designer" immune cells to help patients tolerate their new organ, Medical College of Georgia researchers say.

6 Jul 2009

Atrial fibrillation linked to increased hospitalization in heart failure patients

Patients with atrial fibrillation, common in those with advanced chronic heart failure, have an increased risk of hospitalization due to heart failure, according to new research from researchers at the University of Alabama at Birmingham (UAB).

6 Jul 2009

Research pinpoints difference in the way children with autism learn new behaviors

Researchers from the Kennedy Krieger Institute and Johns Hopkins University School of Medicine have collaborated to uncover important new insights into the neurological basis of autism. Their new study, published in the journal Nature Neuroscience, examined patterns of movement as children with autism and typically developing children learned to control a novel tool.

6 Jul 2009

Delirium in hospitalized adults: Situation critical, no relief available

Every year as many as seven million adults in the United States experience delirium during hospitalization. In a systematic review of the scientific literature on delirium prevention and treatment, investigators from the Regenstrief Institute, Indiana University, and Wishard Health Services found that despite the significant health and financial burdens of delirium for hospitalized adults, no effective way to prevent or treat the condition has been identified.

6 Jul 2009

IU Simon Cancer Center researcher heads cancer study during Indiana Black Expo's health fair

A small drop of blood can provide researchers with countless clues into cancer. You can help researchers at the Indiana University Melvin and Bren Simon Cancer Center by donating a blood sample during the Indiana Black Expo's INShape Indiana Black & Minority Health Fair.

6 Jul 2009

Antidepressants aid electroconvulsive therapy in treating severe depression

Combining antidepressant drugs with electroconvulsive therapy (ECT) does a better job of reducing symptoms of severe depression and causes less memory loss than using ECT alone, according to a new study by researchers at Wake Forest University School of Medicine and colleagues.

6 Jul 2009