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Artificial heart can keep patients awaiting heart transplant alive

The results of the nine-year study of the CardioWest Total Artificial Heart have concluded that the device prevents death in critically ill patients suffering from irreversible failure of both sides of the heart who are candidates for heart transplantation.

26 Aug 2004

Prozac helps treat adolescents with depression

The TADS researchers said that major depressive disorder is common, with one in 20 teens affected at varying levels of severity. Like other forms of depression, major depressive disorder has been associated with increased risk of suicidal behavior and with completed suicide.

26 Aug 2004

Mission to uncover the genetic make-up of Britain

The researchers will take blood from thousands of volunteers all over Britain. The samples will be used to isolate key pieces of DNA that best identify the influences – including Vikings, Saxons, and Celts – shaping regional populations.

26 Aug 2004

Mouse stem cells may help restore hearing loss in humans

The work is important because, in humans, inner ear sensory hair cells are a precious commodity. Humans are born with only about sixteen thousand of these sound detectors in each ear, which can be easily damaged by age, certain illnesses, exposure to loud sounds, and some medications. Once damaged, the cells do not easily grow back. And with the cell loss comes so-called irreversible hearing loss.

26 Aug 2004

Phase 1 clinical trial of new anticancer drug from Human Genome Sciences

Human Genome Sciences has begun dosing patients in a Phase 1 clinical trial of HGS-TR2J, a novel agonistic human monoclonal antibody to TRAIL Receptor 2, in patients with advanced solid malignancies.

25 Aug 2004

High blood pressure increased 30 percent over the last decade in the U.S.

The study found that at least 65 million Americans have hypertension, defined as blood pressure of 140/90 millimeters of mercury (mm Hg) or higher, using blood-pressure lowering medications, or having been told at least twice by a physician or other health professional that they had high blood pressure (medical history). By that definition, almost a third of U.S. adults have hypertension.

25 Aug 2004

Early cholesterol-lowering drug therapy reduces artery-clogging plaque

Early cholesterol-lowering drug therapy after hospitalization for acute coronary syndrome appears to reduce artery-clogging plaque, according to a study reported in Circulation: Journal of the American Heart Association.

25 Aug 2004

New class of compounds play a role in protecting the cardiovascular system

Half a million Americans are diagnosed each year with heart failure, a progressively debilitating condition characterized by the heart's declining ability to pump blood efficiently.

25 Aug 2004

Scientists have discovered a protein that could be the key to finding a cure for asthma

Scientists at the University's Department of Pharmacology and the Woolcock Institute of Medical Research have discovered a protein produced in human lung cells that could be the key to finding a cure for asthma.

25 Aug 2004

High-resolution images reveal the molecular rearrangements that rotavirus uses to break into cells

High-resolution images constructed by researchers at Children's Hospital Boston and Harvard Medical School reveal the molecular rearrangements that rotavirus – the most common cause of severe, dehydrating diarrhea and vomiting in children worldwide – uses to break into cells.

25 Aug 2004

Children who take steroid drugs for nephrotic syndrome do not suffer bone loss

Childhood nephrotic syndrome, which affects 3 out of 100,000 children, is the most common chronic kidney disease in children. Although it does not impair kidney function, it weakens the body's ability to remove water and salt from the blood, and causes swelling in the belly, legs, and around the eyes.

25 Aug 2004

Besides helping infants’ lungs mature, sighs may “reset” breathing regulation mechanism

As if new parents don’t have enough to worry about getting in synch with their infants, many of them wonder “what’s with these sighs?”

25 Aug 2004

Cleaning products and solvents increase risk of asthma

Exposure to the fumes emitted from solvents and cleaning products at home may increase the risk of childhood asthma, suggests a study by Australian researchers from Curtin University and the University of Sydney.

25 Aug 2004

Researchers have identified multiple changes in the gene-expression patterns of cells involved with tumor progression in liver cancer patients

Virginia Commonwealth University researchers have identified multiple changes in the gene-expression patterns of cells involved with tumor progression in liver cancer patients and in those with cirrhosis, which may help scientists predict a person’s risk of developing primary liver cancer.

25 Aug 2004

Spray used by British police forces to control aggressors more harmful than previously thought

The "personal incapacitant" spray or PIS is used for self defence in situations where "lethal force is inappropriate." It combines the compounds CS (o-Chlorobenzylidene malononitrile) with MiBK (Methyl isobutyl keton).

24 Aug 2004

Diabetes and heart disease may stem from fat you can't see

Becoming fat brings conspicuous changes to the shape of the human body, but pioneering research in the Department of Medicine at Flinders University, Australia is working on the theory that the obvious "spare tyre" may not be the major culprit in fat-related diseases.

24 Aug 2004

Space theme tackles obesity and cholesterol levels in youngsters

A supplement entitled “Food and Fitness,” one of three educational guides for teachers produced by Baylor College of Medicine for the NSBRI, teaches middle school students about the importance of nutrition and exercise using intergalactic themes.

23 Aug 2004

Clinicians have been able to reduce mortality rates in HIV positive children from 15 to 3 percent

"This is perhaps the first time that it has been demonstrated that HIV positive children can be successfully treated with antiretroviral therapy in resource-limited settings and the outcomes are comparable to those we have seen in U.S. pediatric antiretroviral clinical trials,"

23 Aug 2004

Researchers find how cancers, particularly lymphomas, develop and might be prevented

Researchers at Children's Hospital Boston have begun unraveling the mystery of how B lymphocytes - key infection-fighting cells in the body - are able to create many different kinds of specialized antibodies through selective gene mutations, while being protected from random mutations that could give rise to cancers.

23 Aug 2004

Researchers have discovered that many people with Bardet-Biedl syndrome can't detect odors

Johns Hopkins researchers have discovered that many people with Bardet-Biedl syndrome (BBS), a rare, complex condition marked by an array of seemingly unconnected symptoms, including obesity, learning difficulties, eye problems and asthma, also have another, previously unreported problem

23 Aug 2004

Medicine News and Research

Artificial heart can keep patients awaiting heart transplant alive

Prozac helps treat adolescents with depression

Mission to uncover the genetic make-up of Britain

Mouse stem cells may help restore hearing loss in humans

Phase 1 clinical trial of new anticancer drug from Human Genome Sciences

High blood pressure increased 30 percent over the last decade in the U.S.

Early cholesterol-lowering drug therapy reduces artery-clogging plaque

New class of compounds play a role in protecting the cardiovascular system

Scientists have discovered a protein that could be the key to finding a cure for asthma

High-resolution images reveal the molecular rearrangements that rotavirus uses to break into cells

Children who take steroid drugs for nephrotic syndrome do not suffer bone loss

Besides helping infants’ lungs mature, sighs may “reset” breathing regulation mechanism

Cleaning products and solvents increase risk of asthma

Researchers have identified multiple changes in the gene-expression patterns of cells involved with tumor progression in liver cancer patients

Spray used by British police forces to control aggressors more harmful than previously thought

Diabetes and heart disease may stem from fat you can't see

Space theme tackles obesity and cholesterol levels in youngsters

Clinicians have been able to reduce mortality rates in HIV positive children from 15 to 3 percent

Researchers find how cancers, particularly lymphomas, develop and might be prevented

Researchers have discovered that many people with Bardet-Biedl syndrome can't detect odors

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