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High-tech approach to combat sepsis

When Jason Martin gives a talk about his research, he begins with the dramatic story of Mariana Bridi da Costa: The young Brazilian supermodel died from severe sepsis in January after amputation of both her hands and feet failed to stop its spread.

15 Jun 2009

Rhinosinusitis may be a factor in toxic shock syndrome in children

Rhinosinusitis (infection and inflammation in the sinus passages surrounding the nose) appears to be a primary factor in about one-fifth of toxic shock syndrome cases in children, according to a report in the June issue of Archives of Otolaryngology-Head & Neck Surgery.

15 Jun 2009

Inflammation of microglia may not be associated with dementia in Alzheimer's disease

The idea that anti-inflammatory drugs might protect people struggling with dementia from Alzheimer's disease has received a blow with the online release of a study of human brain tissue in Acta Neuropathologica.

15 Jun 2009

Non-toxic radioactive patch successfully treats skin cancer

A new study shows that a radioactive skin patch can safely and successfully treat basal cell carcinoma, one of the most common types of skin cancers, according to researchers at the SNM's 56th Annual Meeting. The skin patch, which delivers the radioactive phosphorus-32, is nontoxic and could be an excellent alternative to surgery or radiotherapy in cases where carrying out these treatments is difficult.

15 Jun 2009

Positron emission tomography scans may improve the accuracy of dementia diagnosis

A new study shows that the use of positron emission tomography (PET) scans may improve the accuracy of dementia diagnoses early in disease onset for more than one out of four patients. The results were presented at SNM's 56th Annual Meeting.

15 Jun 2009

Discovery of key molecular target in age-related macular degeneration

A team of researchers led by Dr. Jayakrishna Ambati at the University of Kentucky has discovered a biological marker for neovascular age-related macular degeneration (AMD), the leading cause of blindness in older adults.

15 Jun 2009

Depression may increase risk of Alzheimer's disease in people with memory problems

People with memory problems who are depressed are more likely to develop Alzheimer's disease compared to people who are not depressed, according to a study published in the June 16, 2009, print issue of Neurology, the medical journal of the American Academy of Neurology. However, the research also shows that the popular Alzheimer's drug donepezil may delay the progression to Alzheimer's disease for depressed people with mild cognitive impairment (MCI) or memory problems.

15 Jun 2009

Prevalence of type 2 diabetes in patients with obstructive sleep apnea

A multi-ethnic study in the June 15 issue of the Journal of Clinical Sleep Medicine reports that there is a statistically significant relationship between obstructive sleep apnea (OSA) episodes occurring during rapid eye movement (REM) sleep and type 2 diabetes.

15 Jun 2009

Cancer immunotherapy can use small numbers of ‘stem-like’ immune cells to destroy large tumors in mice

A new approach to stimulating immune cells enhances their anticancer activity, resulting in a powerful anti-tumor response in mice, according to a study by researchers at the National Cancer Institute, a part of the National Institutes of Health. This work represents an important advance in the development of immunotherapy for cancer and appears online June 14, 2009 in Nature Medicine.

15 Jun 2009

New discovery on Huntington's disease

Researchers at the University of Illinois at Chicago College of Medicine have discovered how the mutated huntingtin gene acts on the nervous system to create the devastation of Huntington's disease. The report of their findings is available in Nature Neuroscience online.

15 Jun 2009

A new way to tackle age-related macular degeneration

Researchers at the University of North Carolina at Chapel Hill School of Medicine in collaboration with lead investigators at the University of Kentucky have identified a new target for the diagnosis and treatment of age-related macular degeneration, the most common cause of blindness in older Americans.

15 Jun 2009

Discovery of key gene in deadly inflammatory breast cancer

Aggressive, deadly and often misdiagnosed, inflammatory breast cancer (IBC) is the most lethal form of primary breast cancer, often striking women in their prime and causing death within 18 to 24 months.

15 Jun 2009

Single gene found to control growth of some cancers

Research led by Ashok Aiyar, PhD, Associate Professor of Microbiology at LSU Health Sciences Center New Orleans, showing that a single gene can control growth in cancers related to the Epstein-Barr virus and that existing therapeutics can inactivate it, will be published in the June 12, 2009 online issue of PLoS Pathogens.

15 Jun 2009

Prevention efforts have little success in reducing illness, cost

As health reform heats up, many lawmakers agree that the government should take a larger role in preventing disease. However, the Wall Street Journal reports that "many previous government prevention efforts aimed at costly chronic diseases have had little success in reducing illness or costs."

13 Jun 2009

Democrats prepare for health reform cost analysis while courting GOP votes

What is sure to be a staggering price tag for health reform has Senate Democrats talking about changing the chamber's normal accounting procedures, The Hill reports.

13 Jun 2009

Recent releases: HIV prevention; clinical trials debate; definition of global health; drug resistant tuberculosis

In a Journal of the American Medical Association commentary piece, Anthony Fauci and Carl Dieffenbach of the National Institute of Allergy and Infectious Diseases explore results from a WHO mathematical model study that found universal, voluntary, annual HIV testing followed up with immediate treatment for those testing positive -- the "test and treat model" -- could "reduce HIV incidence" and "end the [HIV] pandemic within 50 years."

13 Jun 2009

International scientists' network to map drug-resistant malaria

PTI/Hindu reports on the Worldwide Antimalarial Resistance Network (WWARN) – an "international network of malaria scientists," which will be "established to map the emergence of resistance" to malaria drugs and "guide global efforts to control and eradicate the disease."

13 Jun 2009

Appetite-stimulating hormone may protect muscle from atrophy

Researchers have found a potential new treatment for the common problem of muscle atrophy. Results of the animal study were presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C.

13 Jun 2009

Adults have much more "brown fat" than previously thought

Keeping your baby fat turns out to be a good thing, as long as it is "brown fat" - the kind that burns calories, according to a study that found adults have much more of this type of fat than previously thought.

13 Jun 2009

Nicotine promotes insulin resistance

Researchers have discovered a reason why smoking greatly increases the risk of heart disease and stroke. Nicotine promotes insulin resistance, also called prediabetes, which is a risk factor for cardiovascular disease, according to the new study, which was presented at The Endocrine Society's 91st Annual Meeting in Washington, D.C.

13 Jun 2009