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Researchers determine how Ki-67 protein disperses chromosomes in dividing cells

Billions of your cells divide every day. Cell division fuels growth and also replaces short-lived cells in some organs, like your skin, blood, and gut.

30 Jun 2016

Study focuses on critical proteins involved in ovarian cancer biology

In what is believed to be the largest study of its kind, scientists at the Pacific Northwest National Laboratory, Johns Hopkins University and their collaborators from institutions across the nation have examined the collections of proteins in the tumors of 169 ovarian cancer patients to identify critical proteins present in their tumors.

30 Jun 2016

New AAV 3.0 program to create next-generation viral vectors for better treatment of inherited diseases

The Perelman School of Medicine at the University of Pennsylvania has launched a new program, called AAV 3.0, to create new viral vectors to find quicker and better treatments for an array of diseases. James M. Wilson, MD, PhD, a professor of Medicine and director of the Orphan Disease Center, will lead an interdisciplinary team of over 30 scientists to create this new technology platform with support provided by the University of Pennsylvania Health System.

30 Jun 2016

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Viruses must avoid a host's immune system to establish successful infections—and scientists have discovered another tool that viruses use to frustrate host defenses.

30 Jun 2016

Study links alpha-defensin genes to IgA nephropathy risk

A gene which forms part of our body's first line of defence against infection may be associated with an increased risk with a type of kidney disease, research involving academics at The University of Nottingham has discovered.

30 Jun 2016

Researchers develop new computational method to track colorectal cancer progression

Team of researchers elaborated a computational method to track the progress of the colorectal cancer. It is a scientific advance that can bring new perspectives to discover the factors that push this pathology and the selection of efficient therapies.

29 Jun 2016

Researchers identify set of genes that play vital role in early human development

Oxford University researchers are closer to solving a decade-old mystery after discovering that a set of genes they are studying play a key role in early human development.

29 Jun 2016

Researchers devise method to identify functional contribution of SIRT6

The enzyme sirtuin 6, or SIRT6, serves many key biological functions in regulating genome stability, DNA repair, metabolism and longevity, but how its multiple enzyme activities relate to its various functions is poorly understood.

29 Jun 2016

Study demonstrates epigenetic link between environment and pubertal onset in humans

Danish researchers have discovered a possible epigenetic link between the environment and pubertal timing.

28 Jun 2016

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Inflammatory myofibroblastic tumors (IMTs) — masses of immune cells— are benign, but poorly understood. Current IMT treatments often have side effects and surgery is sometimes not an option due to the tumor's proximity to vital organs.

28 Jun 2016

Researchers identify exact origin of 2009 swine H1N1 flu pandemic

The 2009 swine H1N1 flu pandemic — responsible for more than 17,000 deaths worldwide — originated in pigs from a very small region in central Mexico, a research team headed by investigators at the Icahn School of Medicine at Mount Sinai is reporting.

28 Jun 2016

Virus-like elements within human genome linked to development of lupus and Sjogren's syndrome

Researchers at Hospital for Special Surgery have uncovered a potential genetic trigger of systemic autoimmune disease.

28 Jun 2016

Study offers array of new insights into nature of Plasmodium vivax

A team of scientists has uncovered the global, evolving, and historic make-up of Plasmodium vivax, one of the five species of malaria that infect humans.

28 Jun 2016

ISU researchers design nanomachine capable of detecting mock version of Ebola virus

Imagine you want to build an intricate work of architecture, like a castle. Now imagine that, once all its individual components are brought together, the castle builds itself automatically. Finally, imagine this castle is so small that it's measured on the same scale as DNA, viruses and small molecules.

28 Jun 2016

Advances in epigenome sequencing technologies can allow comprehensive analysis of cancers

An international research collaboration led by UCL scientists has developed ways to improve the quality and accuracy of information harvested from epigenome sequencing datasets in two new research papers published jointly in Nature Biotechnology and Nature Communications today. According to the studies, epigenome sequencing technologies can allow for more comprehensive analysis of cancers - a key component in the development of targeted approaches to combat cancer.

28 Jun 2016

Novel suite of computer algorithms can accurately predict behavior of gut microbiome

A team of investigators from Brigham and Women's Hospital and the University of Massachusetts have developed a suite of computer algorithms that can accurately predict the behavior of the microbiome - the vast collection of microbes living on and inside the human body.

28 Jun 2016

Oncogene signatures could help design new drug treatments for breast cancer

Drug treatments for breast cancer patients might soon be designed based on the unique genetic autograph of their tumor.

25 Jun 2016

Race impacts adverse outcomes in atrial fibrillation

Black individuals with atrial fibrillation have markedly higher rates of stroke, heart failure, coronary heart disease and mortality than their White counterparts, data from the Atherosclerosis Risk in Communities study show.

24 Jun 2016

Scientists insert metabolic pathway for carbon fixation and sugar production into E. coli bacterium

All life on the planet relies, in one way or another, on a process called carbon fixation: the ability of plants, algae and certain bacteria to "pump" carbon dioxide (CO2) from the environment, add solar or other energy and turn it into the sugars that are the required starting point needed for life processes.

24 Jun 2016

Researchers use sensitive technique to reveal high levels of genetic heterogeneity in schizophrenia

International researchers centered at Nagoya University use a highly sensitive technique to identify significantly more DNA sequence repeats in patients with schizophrenia than in control individuals, and outline a possible link between genome instability and disease.

24 Jun 2016

Genome News and Research

Researchers determine how Ki-67 protein disperses chromosomes in dividing cells

Study focuses on critical proteins involved in ovarian cancer biology

New AAV 3.0 program to create next-generation viral vectors for better treatment of inherited diseases

Researchers reveal novel mechanism by which viral protein VII suppresses immune alarm signals

Study links alpha-defensin genes to IgA nephropathy risk

Researchers develop new computational method to track colorectal cancer progression

Researchers identify set of genes that play vital role in early human development

Researchers devise method to identify functional contribution of SIRT6

Study demonstrates epigenetic link between environment and pubertal onset in humans

Deficiency in NMD could cause inflammatory myofibroblastic tumors

Researchers identify exact origin of 2009 swine H1N1 flu pandemic

Virus-like elements within human genome linked to development of lupus and Sjogren's syndrome

Study offers array of new insights into nature of Plasmodium vivax

ISU researchers design nanomachine capable of detecting mock version of Ebola virus

Advances in epigenome sequencing technologies can allow comprehensive analysis of cancers

Novel suite of computer algorithms can accurately predict behavior of gut microbiome

Oncogene signatures could help design new drug treatments for breast cancer

Race impacts adverse outcomes in atrial fibrillation

Scientists insert metabolic pathway for carbon fixation and sugar production into E. coli bacterium

Researchers use sensitive technique to reveal high levels of genetic heterogeneity in schizophrenia

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