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Early use of antiretroviral treatment improves survival rate of HIV patients

A clinical study, led by researchers from University College Dublin, Ireland, and Stanford University, California, USA, with international collaborators, demonstrates that mortality rates of HIV patients can be almost halved when early antiretroviral (ARV) therapy is added to the treatment of AIDS-related opportunistic infections (OIs) such as pneumonia, meningitis or other serious bacterial infections.

17 May 2009

Variation of natural compound cures malaria in mice

Approximately 350 million to 500 million cases of malaria are diagnosed each year mostly in sub-Saharan Africa. While medications to prevent and treat malaria do exist, the demand for new treatments is on the rise, in part, because malaria parasites have developed a resistance to existing medications.

15 May 2009

New Jersey Senator proposes plan to avert HIV/AIDS drug copayments

New Jersey state Sen. Joseph Vitale (D) -- chair of the Senate Health, Human Services and Senior Citizens Committee -- earlier this week proposed a plan to temporarily reduce rebate checks to senior citizens earning $100,000 to $150,000 in an effort to alleviate the effects of possible budget cuts on certain populations, the Newark Star-Ledger reports. Vitale's proposal also would avert planned $6 to $15 prescription drug copayments for people living with HIV/AIDS in the state (Livio, Newark Star-Ledger, 5/12).

15 May 2009

PIH founder Farmer discussing possible appointment to coordinate U.S. global health initiatives, Boston Globe reports

Paul Farmer -- founder of Partners in Health and vice chair of the Department of Global Health and Social Medicine at Harvard Medical School -- said he is in discussions with the State Department about a possible Obama administration appointment to coordinate U.S. global health initiatives, the Boston Globe reports. Farmer made the announcement Monday during a meeting with HMS faculty.

15 May 2009

Tobacco control must be elevated as a public health priority

An Essay published this week in the open access journal PLoS Medicine calls for the President Obama to "make a strong public commitment" to tobacco control by mobilizing US Government departments and agencies to achieve a coherent policy after eight years of neglect.

15 May 2009

Researchers unravel key mechanism in pathogenesis of osteoporosis

Osteoporosis, or bone loss, is a disease that is most common in the elderly population, affecting women more often than men. Until now, it was not clear exactly how the disease develops.

15 May 2009

Catheter ablation effective for atrial fibrillation

Treating a common heart rhythm disorder by burning heart tissue with a catheter works dramatically better than drug treatments, a major international study has found.

15 May 2009

Morphine patches create addiction

Morphine patches are supposed to reduce use of painkillers, and provide more control over their use in chronic pain conditions. But researchers at the Norwegian University of Science and Technology (NTNU) and St. Olavs Hospital in Trondheim have found otherwise.

15 May 2009

New therapy improves chances of living disease-free with neuroblastoma

A phase III study has shown that adding an antibody-based therapy that harnesses the body's immune system resulted in a 20 percent increase in the number of children living disease-free for at least two years with neuroblastoma.

15 May 2009

Cytomegalovirus may cause high blood pressure

A new study suggests for the first time that cytomegalovirus (CMV), a common viral infection affecting between 60 and 99 percent of adults worldwide, is a cause of high blood pressure, a leading risk factor for heart disease, stroke and kidney disease.

15 May 2009

Old diabetes drug Metformin teaches experts new tricks

Research from the Johns Hopkins Children's Center reveals that the drug most commonly used in type 2 diabetics who don't need insulin works on a much more basic level than once thought, treating persistently elevated blood sugar - the hallmark of type 2 diabetes - by regulating the genes that control its production.

15 May 2009

Obese, older and poorer Australians get more chronic diseases

According to researchers at the University of Adelaide, in the past 15 years chronic diseases among older, lower income and obese Australians have increased significantly.

15 May 2009

Herpes drug Acyclovir does not reduce risk of HIV transmission, does slow HIV progression, study says

The drug acyclovir, which suppresses herpes simplex virus-2, does not reduce the risk of HIV transmission when taken by HIV-positive people who also have herpes, according to a study conducted by researchers at the University of Washington, United Press International reports.

14 May 2009

Discovery of two proteins essential for ovulation

Researchers from the National Institutes of Health and other institutions have identified in mice two proteins essential for ovulation to take place.

14 May 2009

Implanted cardioverter defibrillators extend lives of heart attack survivors by a year

A landmark follow-up study found that heart attack survivors who receive implanted cardioverter defribillators (ICDs) live longer the longer they have them, according to the results of alate-breaking clinical trail presented today at the annual Scientific Sessions of the Heart Rhythm Society.

14 May 2009

Cimzia approved in U.S. for rheumatoid arthritis

UCB announced today that the U.S. Food and Drug Administration (FDA) approved Cimzia, the only PEGylated anti-TNF (Tumor Necrosis Factor), for the treatment of adult patients with moderately to severely active rheumatoid arthritis (RA).

13 May 2009

Baylor Research Institute receives multi-million dollar grant to develop flu vaccine

Scientists at Baylor Institute for Immunology Research (BIIR) in Dallas, part of Baylor Research Institute (BRI) and the Baylor Health Care System, announced today that they received a renewal of a multi-million dollar grant from the National Institutes of Health (NIH) to design new vaccines to prevent influenza - including swine flu (H1N1).

13 May 2009

Chemo improves survival among older breast cancer patients

The average age of a woman diagnosed with breast cancer is 63, so it is critical to have effective proven, therapies for an older patient population. But older women with breast cancer are underrepresented in clinic trials, so there is little data on the effects of chemotherapy used in addition to other therapies such as surgery.

13 May 2009

Researchers demonstrate the immunological effects of ginseng

Researchers writing in BioMed Central's open access Journal of Translational Medicine have shown that the herb, much used in traditional Chinese and other Asian medicine, does have anti-inflammatory effects.

13 May 2009

Research shows how cocaine regulates gene expression in a crucial reward region

The study, published by Cell Press in the May 14th issue of the journal Neuron, provides exciting insight into the molecular pathways regulated by cocaine and may lead to new strategies for battling drug addiction.

13 May 2009