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Drugs to activate STING could help prevent cancer metastasis

A team of scientists at the Sloan Kettering Institute have identified the STING cellular signaling pathway as a key player in keeping dormant cancer cells from progressing into aggressive tumors months, or even years, after they've escaped from a primary tumor.

29 Mar 2023

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

Increases in multidrug-resistance in the bacteria Streptococcus pneumoniae have made it the fourth-leading cause of death associated with antibiotic resistance.

29 Mar 2023

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, potentially leading to new drugs against COVID-19, University of Gothenburg researchers show.

29 Mar 2023

Advanced pancreatic cancer model more accurately depicts PDAC tumor progression

Pancreatic ductal adenocarcinoma (PDAC), is highly aggressive and lethal. It is the most prevalent type of pancreatic cancer, making up 90% of cases; it also has a high rate of metastasis, with an average five-year survival rate of less than 10%.

29 Mar 2023

People with allergic diseases may be at heightened risk of osteoarthritis

People with atopic (allergic) diseases like asthma or eczema may be at heightened risk of the painful and often disabling joint condition, osteoarthritis, finds research published online in the Annals of the Rheumatic Diseases.

29 Mar 2023

Hematology patients generate robust immune responses against SARS-CoV-2 after vaccination

Researchers found that, despite being heavily immunocompromised, hematology patients generate strong cellular immune responses against SARS-CoV-2 after vaccination, on par with that of healthy individuals.

29 Mar 2023

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

A National Institutes of Health team has identified a compound already approved by the U.S. Food and Drug Administration that keeps light-sensitive photoreceptors alive in three models of Leber congenital amaurosis type 10 (LCA 10), an inherited retinal ciliopathy disease that often results in severe visual impairment or blindness in early childhood.

29 Mar 2023

The emergence of lateral flow assays in diagnostics

In this interview, News-Medical talks to Hasret Altan-Martin from Sartorius about the ongoing emergence of lateral flow assays in diagnostics.

From Sartorius Lab Instruments GmbH & Co. KG 29 Mar 2023

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

Researchers compared the effects of consuming red-fleshed apples and white-fleshed among healthy adults.

29 Mar 2023

A progress check on hospital price transparency

For decades, U.S. hospitals have generally stonewalled patients who wanted to know ahead of time how much their care would cost. Now that's changing — but there's a vigorous debate over what hospitals are disclosing.

29 Mar 2023

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Study outlines molecular mechanisms to aid the development of new therapies to manage obesity and associated health disorders.

29 Mar 2023

Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors

Researchers reviewed the importance of the circadian rhythm in the formation and progression of tumors.

29 Mar 2023

Next-generation influenza vaccines show greater impact and cost-effectiveness, study suggests

In a recent study published in the BMC Medicine Journal, researchers conducted a modeling study to evaluate the cost-effectiveness and health impacts of the next-generation vaccines against influenza in Kenya.

28 Mar 2023

Advancements and challenges of constructing artificial mitochondria and chloroplasts

Energy production in nature is the responsibility of chloroplasts and mitochondria and is crucial for fabricating sustainable, synthetic cells in the lab.

28 Mar 2023

COVID-19 activates endogenous retroviruses within our genome

Researchers assess the impact of SARS-CoV-2 infection on endogenous retroviruses of the LTR69 subfamily.

28 Mar 2023

New Mediterranean plant-based smoothies show promising health benefits, study finds

A recent study published in the Antioxidants journal analyzed the potential health-promoting activities of innovative smoothies made from some typical Mediterranean plant products, such as apple (Malus domestica (Md) juice, strawberry tree (Arbutus unedo (Au) fruit puree and enriched with Myrtus communis (Mc) purple berry extract, Crocus sativus (Cs) petal juice, Acca sellowiana (As), and Diospyros kaki (Dk) fruits.

28 Mar 2023

Grape polyphenols reduce angiogenesis in adipose tissue during overfeeding weight gain

A study published in the Journal of Nutritional Biochemistry investigated the changes in gene expressions during an overfeeding episode. It demonstrated that supplementation of grape polyphenols in healthy lean men modulates the expression of genes related to adipose tissue angiogenesis.

28 Mar 2023

Capsaicin and its health benefits

Researchers examine the health benefits associated with capsaicin, with a particular focus on how this compound impacts cognition and cardiovascular health.

28 Mar 2023

Understanding how to better prescribe probiotics based on our individual microbiome profiles

Bacteria have thousands of genes and functions that we, the human host, do not have. For instance, bacteria can help us digest fiber, provide support to our immune systems, and absorb important nutrients. But reaping the benefits of "good bacteria" is easier said than done.

28 Mar 2023

Study shows how RNA biomarkers may be used to confirm heart disease

When patients begin to experience chest pain or shortness of breath while exercising, doctors may struggle to correctly diagnose if the problem is caused by coronary artery disease.

28 Mar 2023

B Cell News and Research

Drugs to activate STING could help prevent cancer metastasis

Study offers a novel therapeutic option to combat antibiotic-resistant pneumonia

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Advanced pancreatic cancer model more accurately depicts PDAC tumor progression

People with allergic diseases may be at heightened risk of osteoarthritis

Hematology patients generate robust immune responses against SARS-CoV-2 after vaccination

FDA-approved drug keeps light-sensitive photoreceptors alive in lab models of LCA 10

The emergence of lateral flow assays in diagnostics

An apple a day keeps the doctor away: polyphenol-enriched apples alter immune cell gene expression and fecal microbiota composition

A progress check on hospital price transparency

Targeting obesity: findings reveal a new molecular pathway involved in energy homeostasis regulation

Clockwork in cancer: the importance of the circadian rhythm in the formation and progression of tumors

Next-generation influenza vaccines show greater impact and cost-effectiveness, study suggests

Advancements and challenges of constructing artificial mitochondria and chloroplasts

COVID-19 activates endogenous retroviruses within our genome

New Mediterranean plant-based smoothies show promising health benefits, study finds

Grape polyphenols reduce angiogenesis in adipose tissue during overfeeding weight gain

Capsaicin and its health benefits

Understanding how to better prescribe probiotics based on our individual microbiome profiles

Study shows how RNA biomarkers may be used to confirm heart disease

Using single B cell screening to boost antibody discovery eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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