Amino Acid News and Research

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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.

SARS-CoV-2 mutational spectra based on reconstructed phylogenetic tree

In a new study, researchers assessed the impact of mutagenesis on the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) genome and the effects of mutations in the neutral regions and non-neutral regions of the genome.

25 Aug 2022

Virtual screening and molecular dynamics explore potential repurposed drugs against monkeypox virus

A recent study investigated ‘targets’ in the poxvirus and identified the protein residues active in MPV, following which eight potential anti-viral drugs were proposed.

25 Aug 2022

What is the stability of SARS-CoV-2 strains in human biological fluids?

In a new study, researchers assessed the stability of ancestral severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) lineage in human biological fluids.

24 Aug 2022

Surprising culprit contributes significantly to the brain destruction after stroke or TBI

In the aftermath of a stroke or TBI, a group of amino acids that typically support brain function contribute significantly to the brain destruction that can follow both these injuries, scientists report.

23 Aug 2022

Epistasis leads to the reduction in genetic barrier to COVID-19 neutralizing antibody escape

A new study addresses the important question of how the SARS-CoV-2 virus would evolve in the future to be able to escape diverse and broadly neutralizing antibodies.

23 Aug 2022

How natural alterations inside the SARS-CoV-2 glycan barrier affect spike protein dynamics

Researchers explored how the natural alterations inside the SARS-CoV-2 glycan barrier affect the spike protein dynamics.

22 Aug 2022

Intake of lysine prevents hypertensive kidney disease in animal models

Can you eat your way out of a kidney disease? Perhaps you can – according to a new study from Aarhus University.

19 Aug 2022

SARS-CoV-2 variant neutralization and novel mAbs reveal protection against Omicron in new research

Researchers assessed the SARS-CoV-2 variants of concern (VOCs) transmission dynamics and neutralization by vaccine-induced antibodies and monoclonal antibodies (mAbs).

19 Aug 2022

What drugs can be repurposed for monkeypox therapy?

In new research, researchers repurposed medications for the monkeypox virus in silico.

16 Aug 2022

Post-illness metabolomic and gut-microbiome profiles in community-dwelling participants with SARS-CoV-2

Researchers explored post-illness gut-microbiome and metabolomic profiles of community COVID-19 cases and individuals with non-COVID-19 illnesses of prolonged duration.

15 Aug 2022

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

Researchers investigated the susceptibility of naturally-occurring severe acute respiratory syndrome coronavirus 2 main protease variants to protease inhibitor drugs, including nirmatrelvir and ensitrelvir.

11 Aug 2022

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

The current study, published online in the journal JHEP Reports, looks at PFAS, which are endocrine disruptors and potential hepatotoxins.

11 Aug 2022

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

A new study, led by researchers from the University of California, Irvine and the University of California, San Diego, reveals a new computation-guided approach to identify small molecules that can restore aspects of wild-type p53 tumor suppression function to mutated p53, which play an important role in many human cancers.

11 Aug 2022

Scientists conduct comparative analysis of monkeypox virus profilin-like proteins and human profilin proteins

In a new study, researchers explored monkeypox virus proteomics and structural characteristics of the A42R protein, the only MPXV protein in the RCSB PDB (protein data bank) and the only profilin-like protein of poxviruses with known structure.

10 Aug 2022

Scientists present highly accurate novel framework for SARS-CoV-2 genomic surveillance

Researchers presented a novel framework for SARS-CoV-2 genomic surveillance based on case studies from New York, the United States, and the United Kingdom in a new study.

10 Aug 2022

Antibody evasion of Omicron BA.2.75 is less pronounced than BA.4/5

Researchers assess the sensitivity of the SARS-CoV-2 Omicron BA.2.75 sublineage to neutralization.

9 Aug 2022

Exposure to a synthetic “forever chemical” linked to non-viral hepatocellular carcinoma

Exposure to a synthetic chemical found widely in the environment is linked to non-viral hepatocellular carcinoma, the most common type of liver cancer, according to a new study conducted by researchers from the Keck School of Medicine of USC and published in JHEP Reports.

9 Aug 2022

Study reveals key similarities between the nervous system of two early-diverging animal lineages

Neurons, the specialized cells of the nervous system, are possibly the most complicated cell type ever to have evolved. In humans, these cells are capable of processing and transmitting vast sums of information. But how such complicated cells first came about remains a long-standing debate.

9 Aug 2022

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

News-Medical speaks to Dr. Cicely Fadel and Amir Bein about their latest research which involved the development of an Environmental Enteric Dysfunction (EED) Chip that reveals the effects of nutrition and genetics on disease in children

8 Aug 2022

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

Scientists at Duke-NUS Medical School in Singapore have uncovered a mechanism that leads to an advanced form of fatty liver disease - and it turns out that vitamin B12 and folic acid supplements could reverse this process.

5 Aug 2022

Amino Acid News and Research

Further Reading

SARS-CoV-2 mutational spectra based on reconstructed phylogenetic tree

Virtual screening and molecular dynamics explore potential repurposed drugs against monkeypox virus

What is the stability of SARS-CoV-2 strains in human biological fluids?

Surprising culprit contributes significantly to the brain destruction after stroke or TBI

Epistasis leads to the reduction in genetic barrier to COVID-19 neutralizing antibody escape

How natural alterations inside the SARS-CoV-2 glycan barrier affect spike protein dynamics

Intake of lysine prevents hypertensive kidney disease in animal models

SARS-CoV-2 variant neutralization and novel mAbs reveal protection against Omicron in new research

What drugs can be repurposed for monkeypox therapy?

Post-illness metabolomic and gut-microbiome profiles in community-dwelling participants with SARS-CoV-2

Study highlights the urgent need for combinatorial drug therapies for SARS-CoV-2

What is the association between polyfluoroalkyl substance exposure and risk of non-viral hepatocellular carcinoma?

New computation-guided approach to identify small molecule corrector drugs for p53 hotspot mutations

Scientists conduct comparative analysis of monkeypox virus profilin-like proteins and human profilin proteins

Scientists present highly accurate novel framework for SARS-CoV-2 genomic surveillance

Antibody evasion of Omicron BA.2.75 is less pronounced than BA.4/5

Exposure to a synthetic “forever chemical” linked to non-viral hepatocellular carcinoma

Study reveals key similarities between the nervous system of two early-diverging animal lineages

Human intestine-on-a-chip for modeling intestinal injury associated with a pediatric inflammatory disorder

Vitamin B12, folic acid supplements could potentially halt or reverse advanced form of fatty liver disease

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