Amino Acid News and Research

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Amino Acid is one of several molecules that join together to form proteins. There are 20 common amino acids found in proteins.

SARS-CoV-2 N escape mutations do not affect rapid antigen testing

A new study maps the escape mutations found in various strains of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that could cause them to escape neutralization by antibodies or detection by rapid antigen tests that rely on antibody binding for a positive result.

16 Sep 2022

Machine learning can help create proteins much more accurately, quickly than previously possible

Over the past two years, machine learning has revolutionized protein structure prediction. Now, three papers in Science describe a similar revolution in protein design.

15 Sep 2022

Scientists unravel the molecular origin of rare genetic disease cystinosis

The rare genetic disease cystinosis is caused by mutations in the gene for a protein called cystinosin. A team of scientists has now solved the structure of cystinosin and determined how mutations interfere with its normal function, providing insights into the underlying mechanisms and suggesting a way to develop new treatments for the disease.

15 Sep 2022

New method evaluates how mutations to SARS-CoV-2 can affect antibody recognition in rapid antigen tests

A research team funded by the National Institutes of Health has shown that commercially available rapid antigen tests can detect past and present variants of concern and has identified potential mutations that may impact test performance in the future.

15 Sep 2022

MIT researchers use new technique to gather insight into repetitive protein sequences

About 70 percent of all human proteins include at least one sequence consisting of a single amino acid repeated many times, with a few other amino acids sprinkled in. These "low-complexity regions" are also found in most other organisms.

13 Sep 2022

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

In a recent study posted to the medRxiv* preprint server, researchers in Australia determined whether severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta-ORF7aΔ17del [open reading frame 7a protein with 17-nucleotide (nt) frameshift-inducing deletion] variant has a fitness advantage over the Delta variant lacking the ORF7aΔ17del deletion (Delta-ORF7aintact) and/or the SARS-CoV-2 lineage (A.2.2).

12 Sep 2022

Researchers uncover the structure of protein fibrils linked to hereditary form of human prion disease

In a new study, researchers from the Case Western Reserve University School of Medicine have identified the structure of protein fibrils linked to a hereditary form of human prion disease.

12 Sep 2022

Role of the transketolase-like 1 gene in the development of the modern human brain

In a new study, researchers demonstrated how transketolase-like 1 (TKTL1) gene expression influenced neocortical neurogenesis in modern humans.

12 Sep 2022

Dissecting vaccinia virus and monkeypox virus-specific T cell responses in humans

In a new study, a team of researchers studied different antigens targeted by vaccinia virus (VACV)- and monkeypox virus (MPXV)-specific T cells.

12 Sep 2022

Understanding the molecular pathways that underly nutrient switch in starving cancer cells

Cancer cells often grow in environments that are low in nutrients, and they cope with this challenge by switching their metabolism to using proteins as alternative "food".

9 Sep 2022

Study helps understand how dietary therapies work for epilepsy

Calorie restriction has long been associated with reduced seizures in epilepsy. New research from Boston Children's Hospital helps explain how fasting affects neurons in the brain and could lead the way to new approaches that would avoid the need for fasting or restrictive diets. The findings were published August 30 in the journal Cell Reports.

9 Sep 2022

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

Researchers from Dresden uncover a greater neuron production in the frontal lobe during brain development in modern humans than Neandertals, due to the change of a single amino acid in the protein TKTL1.

9 Sep 2022

A single genomic change may have given modern humans an advantage over Neanderthals

A single amino acid change in the transketolase-like 1 (TKTL1) protein may have given modern humans an advantage over more ancient contemporaries like Neanderthals by enabling increased neocortical neurogenesis, researchers report.

9 Sep 2022

Supplementary folic acid associated with higher risk of COVID-19 diagnosis and mortality

In a recent study published in the journal BMJ Open, researchers investigated the impact of folic acid supplements and methotrexate, in combination or individually, on disease severity and mortality in coronavirus disease 2019 (COVID-19) cases.

8 Sep 2022

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

Researchers at the Johns Hopkins Kimmel Cancer Center, three other cancer centers and the Johns Hopkins Bloomberg School of Public Health compiled a comprehensive genetic architecture atlas for mutant RAS genes in human cancers.

8 Sep 2022

The effects of taurine supplementation on biomarkers of oxidative stress in women aged 55 to 70

Researchers investigated the effects of supplementing taurine on the biomarkers of oxidative stress in females.

8 Sep 2022

Advances in modeling molecular interactions needed to better harness AlphaFold for drug discovery

Over the past few decades, very few new antibiotics have been developed, largely because current methods for screening potential drugs are prohibitively expensive and time-consuming.

6 Sep 2022

The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

Scientists have described the epidemiology, transmission, clinical features, diagnosis, treatment, and preventive strategies of monkeypox infection among humans.

6 Sep 2022

Sensitivity of SARS-CoV-2 Omicron BA.2.75 to neutralization by monoclonal antibodies and sera

Researchers assessed the sensitivity of the SARS-CoV-2 Omicron subvariant BA.2.75 spike protein to neutralization by monoclonal antibodies and sera obtained from Swedish individuals.

5 Sep 2022

What is the infectivity of SARS-CoV-2 Omicron BA.2.75 variant?

Researchers recently assessed the infectivity of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.2.75 variant compared to preexisting variants.

30 Aug 2022

Amino Acid News and Research

Further Reading

SARS-CoV-2 N escape mutations do not affect rapid antigen testing

Machine learning can help create proteins much more accurately, quickly than previously possible

Scientists unravel the molecular origin of rare genetic disease cystinosis

New method evaluates how mutations to SARS-CoV-2 can affect antibody recognition in rapid antigen tests

MIT researchers use new technique to gather insight into repetitive protein sequences

First report of a SARS-CoV-2 variant with an ORF7a deletion that dominated an outbreak

Researchers uncover the structure of protein fibrils linked to hereditary form of human prion disease

Role of the transketolase-like 1 gene in the development of the modern human brain

Dissecting vaccinia virus and monkeypox virus-specific T cell responses in humans

Understanding the molecular pathways that underly nutrient switch in starving cancer cells

Study helps understand how dietary therapies work for epilepsy

Single amino acid change in TKTL1 protein underlies greater neuron production in modern humans than Neandertals

A single genomic change may have given modern humans an advantage over Neanderthals

Supplementary folic acid associated with higher risk of COVID-19 diagnosis and mortality

Comprehensive genetic architecture atlas compiled for mutant RAS genes in cancers

The effects of taurine supplementation on biomarkers of oxidative stress in women aged 55 to 70

Advances in modeling molecular interactions needed to better harness AlphaFold for drug discovery

The virology, epidemiology, transmission, clinical manifestations, diagnosis, management, and prevention strategies associated with monkeypox

Sensitivity of SARS-CoV-2 Omicron BA.2.75 to neutralization by monoclonal antibodies and sera

What is the infectivity of SARS-CoV-2 Omicron BA.2.75 variant?

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