Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Researchers identify link between GPR126 gene and adolescent idiopathic scoliosis

Researchers from the RIKEN Center for Integrative Medical Sciences in Japan have identified the first gene to be associated with adolescent idiopathic scoliosis (also called AIS) across Asian and Caucasian populations.

13 May 2013

Fat cells in knee secrete a protein linked to arthritis

Scientists have discovered that fat cells in the knee secrete a protein linked to arthritis, a finding that paves the way for new gene therapies that could offer relief and mobility to millions worldwide.

10 May 2013

Solder for laser welding of tissue produces stronger seals during intestinal surgery

A new "solder" for laser welding of tissue during surgical operations has the potential to produce stronger seals and expand use of this alternative to conventional sutures and stapling in intestinal surgery, scientists are reporting. Their study, which involves use of a gold-based solder, or sealing material, appears in the journal ACS Nano.

9 May 2013

EPSRC-funded study explores feasibility of using natural fibres for cartilage repair

Over 20 million people in Europe suffer from osteoarthritis which can lead to extensive damage to the knee and hip cartilage. Stem cells offer a promising way forward but a key challenge has been to design a 'smart material' that is biologically effective for cartilage tissue regeneration. Now researchers have identified a blend of naturally occurring fibres such as cellulose and silk that makes progress towards affordable and effective cell-based therapy for cartilage repair a step closer

8 May 2013

New joint lubricant brings longer lasting relief to osteoarthritis sufferers

A team of researchers led by a Boston University Biomedical Engineer has developed a new joint lubricant that could bring longer lasting relief to millions of osteoarthritis sufferers.

3 May 2013

EntreMed announces issuance of patent for clinical-stage compound, 2-methoxyestradiol

EntreMed, Inc., a clinical-stage pharmaceutical company developing therapeutics for the treatment of a variety of cancers, announced the issuance of a U.S. patent covering methods of treatment and formulations for its clinical-stage compound, 2-methoxyestradiol.

3 May 2013

Researchers create novel way to enhance MRI

Researchers at New York University and NYU Langone Medical Center have created a novel way to enhance MRI by reducing interference from large macromolecules that can often obscure images generated by current chemical exchange saturation transfer methods.

30 Apr 2013

Upcoming symposium to offer highlights of 150-year history of Hospital for Special Surgery

An upcoming symposium will offer highlights of the 150-year history of Hospital for Special Surgery and at the same time provide a fascinating look at the evolution of medicine from the "Dark Ages" of the Civil War period to modern medicine as we know it today.

29 Apr 2013

Ampio completes patient enrollment in dose-escalation run-in study of Ampion for treatment of knee osteoarthritis

Ampio Pharmaceuticals, Inc. today announced the completion of patient enrollment in a dose-escalation run-in study to a Phase III pivotal trial evaluating Ampion in the treatment of moderate to severe osteoarthritis of the knee.

26 Apr 2013

Biological imaging technologies create a new way to learn about cells

Researchers have married two biological imaging technologies, creating a new way to learn how good cells go bad. "Let's say you have a large population of cells," said Corey Neu, an assistant professor in Purdue University's Weldon School of Biomedical Engineering.

26 Apr 2013

Tissue engineering combined with gene therapy can manage repair of defective articular cartilage

Researchers at Micro Orthopaedics, Zhongnan Hospital of Wuhan University, led by Dr. Ai-xi Yu, have suggested that articular cartilage defects can be repaired by a novel thermo-sensitive injectable hydrogel engineered with gene modified bone marrow mesenchymal stromal cells.

24 Apr 2013

Rheumatoid arthritis diagnosis: an interview with Dr. Stan Naides, Medical Director, Quest Diagnostics

Rheumatoid arthritis (RA) is an autoimmune disorder that can cause debilitating joint damage. In cases of RA, the immune system attacks the body’s own tissues, especially the membranes that line the joints. As a result, fluid builds up in the joints, causing pain and systemic inflammation, leading to joint destruction if untreated.

From Quest Diagnostics 23 Apr 2013

$Young athletes undergoing intense training have higher risk of stress fractures, other overuse injuries$

Young athletes undergoing intense training have higher risk of stress fractures, other overuse injuries

Young athletes who specialize in one sport and train intensively have a significantly higher risk of stress fractures and other severe overuse injuries, even when compared with other injured athletes, according to the largest clinical study of its kind.

22 Apr 2013

Researcher discovers additional mechanical properties of articular cartilage result in osteoarthritis

A researcher at The Feinstein Institute for Medical Research has discovered additional mechanical properties of articular cartilage, a protective cartilage on the ends of bones that wears down over time, resulting in the development of osteoarthritis.

20 Apr 2013

Hospital for Special Surgery to host educational symposium to discuss on sports-related injuries

Hospital for Special Surgery, the nation's top hospital for orthopedics, will host Current Concepts in Sports Medicine, an educational symposium to discuss how to identify, prevent and treat articular cartilage and hip/pelvis injuries, as well as injuries common to the throwing and multisport athlete.

19 Apr 2013

Running or jumping may worsen cartilage damage, MIT engineers find

Osteoarthritis, which affects at least 20 percent of adults in the United States, leads to deterioration of cartilage, the rubbery tissue that prevents bones from rubbing together.

18 Apr 2013

Bioactive plasma-based biomaterials can accelerate tissue healing

Platelet-rich plasma derived from blood contains growth factors and other bioactive molecules that promote healing at sites of tissue injury. However, it is difficult to deliver and retain these molecules at a target site, and clinical results have proven to be mixed - until now.

16 Apr 2013

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