Developmental Biology News and Research

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Intrinsically disordered proteins have ability to alter their configuration

Like the shape-shifting robots of "Transformers" fame, a unique class of proteins in the human body also has the ability to alter their configuration. These so-named intrinsically disordered proteins (IDPs) lack a fixed or ordered three-dimensional structure, which can be influenced by exposure to various chemicals and cellular modifications.

26 Feb 2015

AXT establishes preclinical imaging portfolio with MR solutions product lines

To coincide with the start of Lorne Cancer conference, AXT are proud to announce the commencement of their distributorship with MR SOLUTIONS, a world leader in the development of innovative preclinical imaging solutions

From MR Solutions 11 Feb 2015

DNA strands predict life expectancy

BYU biologist Jonathan Alder has a startling secret he doesn't freely share: he knows when most of us are going to die.

9 Feb 2015

Marie Csete appointed president and chief scientist of HMRI

Huntington Medical Research Institutes, a leading biomedical research organization, has announced the appointment of Marie Csete, MD, PhD, its chief scientific officer, to her new role as president and chief scientist of HMRI.

29 Jan 2015

Cardiac regeneration strategies need to be based on severity of heart injury

A new study by researchers at Children's Hospital Los Angeles has shown that neonatal mouse hearts have varying regenerative capacities depending upon the severity of injury. Using cryoinjury - damaging the heart through exposure to extreme cold in order to mimic cellular injury caused by myocardial infarction - investigators found that neonatal mouse hearts can fully recover normal function following a mild injury, though fail to regenerate after a severe injury.

23 Jan 2015

Scientists identify gene that helps regulate development of central nervous system

Scientists have identified a gene that helps regulate how well nerves of the central nervous system are insulated, researchers at Washington University School of Medicine in St. Louis report.

23 Jan 2015

Findings could lead to new therapeutic approach to Parkinson's disease

E.. coli usually brings to mind food poisoning and beach closures, but researchers recently discovered a protein in E.. coli that inhibits the accumulation of potentially toxic amyloids--a hallmark of diseases such as Parkinson's.

23 Jan 2015

UAB Research Probes Molecular Basis Of Rare Genetic Disorder

An international group co-led by University of Alabama at Birmingham researcher Mary MacDougall, Ph.D., has unraveled the molecular basis for the rare, inherited genetic disorder, Singleton-Merten Syndrome (SMS). Individuals with SMS develop extreme, life-threatening calcification of the aorta and heart valves, early-onset periodontitis and root resorption of the teeth, decreases in bone density, and loss of bone tissue at the tips of fingers and toes.

23 Jan 2015

CHLA scientists grow tissue-engineered small intestine from human cells

A new study by researchers at Children's Hospital Los Angeles has shown that tissue-engineered small intestine grown from human cells replicates key aspects of a functioning human intestine. The tissue-engineered small intestine they developed contains important elements of the mucosal lining and support structures, including the ability to absorb sugars, and even tiny or ultra-structural components like cellular connections.

9 Jan 2015

Olympus BioScapes Digital Imaging Competition 2014 winners announced

From algae to zebrafish, life under the microscope can be beautiful, surprising and mysterious. This week, amazing glimpses of the unseen universe earned top prizes in the 2014 Olympus BioScapes Digital Imaging Competition®, the world’s foremost forum for showcasing microscope images of life science subjects.

From Evident Corporation - Life Sciences 16 Dec 2014

UT Southwestern researchers identify possible therapy to treat neurofibromatosis type 1

UT Southwestern Medical Center researchers have identified a possible therapy to treat neurofibromatosis type 1 or NF1, a childhood neurological disease characterized by learning deficits and autism that is caused by inherited mutations in the gene encoding a protein called neurofibromin.

15 Dec 2014

Leica Microsystems offers preview of light sheet module for confocal microscope at ASCB annual meeting

At the annual meeting of the American Society for Cell Biology (ASCB) in Philadelphia, PA, USA, from December 6 to 10, 2014, Leica Microsystems offers visitors a preview of its latest development: a light sheet module as an optional add-on to the Leica TCS SP8 confocal microscope for the observation of developing organisms in real time and 3D. The synergy of light sheet and confocal microscopy opens novel fields of application.

From Leica Microsystems GmbH 5 Dec 2014

Biologist Marnie Halpern selected as AAAS Fellow

Biologist Marnie Halpern of Carnegie's Department of Embryology has been named a Fellow of the American Association for the Advancement of Science (AAAS) for her "fundamental contributions to developmental biology, particularly using novel genetic approaches to study patterning of the nervous system."

26 Nov 2014

UT Southwestern researchers identify new gene mutations involved in certain kidney cancers

Using next generation gene sequencing techniques, cancer researchers at UT Southwestern Medical Center have identified more than 3,000 new mutations involved in certain kidney cancers, findings that help explain the diversity of cancer behaviors.

17 Nov 2014

Microscope objectives for ultra-deep biological imaging introduced by Olympus

Two dedicated microscope objectives optimized for deep, high-resolution imaging of life science specimens up to 8mm beneath the surface have been introduced by Olympus.

From Evident Corporation - Life Sciences 13 Nov 2014

Researchers reconstruct early stages of mammalian development using embryonic stem cells

Researchers at the University of Cambridge have managed to reconstruct the early stage of mammalian development using embryonic stem cells, showing that a critical mass of cells – not too few, but not too many – is needed for the cells to being self-organising into the correct structure for an embryo to form.

6 Nov 2014

BYU study: Exposure to cigarette smoke can cause weight gain

New research is challenging the decades-old belief that smoking cigarettes helps keep you slim.

5 Nov 2014

Scratching itchy skin causes the brain to release serotonin, intensifies itchy feeling

Turns out your mom was right: Scratching an itch only makes it worse. New research from scientists at Washington University School of Medicine in St. Louis indicates that scratching causes the brain to release serotonin, which intensifies the itch sensation.

31 Oct 2014

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Recent breakthroughs may pave the way for vaccines and new drugs for those infected by parasitic helminths. These flatworms, including tapeworms that cause hydatid diseases and neurocysticercosis, liver flukes, and blood flukes (schistosomes), infect more than 300 million people and cause approximately four million disability-adjusted life years lost due to chronic illness and death each year.

28 Oct 2014

Research: MHCI protein moonlights in nervous system to regulate synapses

When it comes to the brain, "more is better" seems like an obvious assumption. But in the case of synapses, which are the connections between brain cells, too many or too few can both disrupt brain function.

21 Oct 2014

Developmental Biology News and Research

Intrinsically disordered proteins have ability to alter their configuration

AXT establishes preclinical imaging portfolio with MR solutions product lines

DNA strands predict life expectancy

Marie Csete appointed president and chief scientist of HMRI

Cardiac regeneration strategies need to be based on severity of heart injury

Scientists identify gene that helps regulate development of central nervous system

Findings could lead to new therapeutic approach to Parkinson's disease

UAB Research Probes Molecular Basis Of Rare Genetic Disorder

CHLA scientists grow tissue-engineered small intestine from human cells

Olympus BioScapes Digital Imaging Competition 2014 winners announced

UT Southwestern researchers identify possible therapy to treat neurofibromatosis type 1

Leica Microsystems offers preview of light sheet module for confocal microscope at ASCB annual meeting

Biologist Marnie Halpern selected as AAAS Fellow

UT Southwestern researchers identify new gene mutations involved in certain kidney cancers

Microscope objectives for ultra-deep biological imaging introduced by Olympus

Researchers reconstruct early stages of mammalian development using embryonic stem cells

BYU study: Exposure to cigarette smoke can cause weight gain

Scratching itchy skin causes the brain to release serotonin, intensifies itchy feeling

Research breakthroughs may pave way for new drugs to fight against parasitic worm infections

Research: MHCI protein moonlights in nervous system to regulate synapses

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