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Defective ASTN1 gene linked to developmental delay and neurological disorders

Nearly 30 years ago, researchers began studying the gene Astn1, which encodes the cell adhesion protein astrotactin 1 in mice, and its role in brain development.

10 Feb 2026

'Partial reprogramming' of engram neurons restores memory performance in mice

Age-related memory decline and neurodegenerative diseases like Alzheimer's are often thought of as irreversible.

10 Feb 2026

New guidance for the diagnosis and management of inherited hyperbilirubinemia

Inherited hyperbilirubinemia, encompassing Gilbert syndrome, Crigler-Najjar syndrome, Dubin-Johnson syndrome, and Rotor syndrome, represents a spectrum of disorders rooted in genetic defects affecting bilirubin metabolism and transport.

10 Feb 2026

Engineered wax moths offer ethical alternative to rodents used in research

A scientific breakthrough not only promises faster testing for antimicrobial resistance, but also an ethical solution to the controversial issue of using rodents in research.

10 Feb 2026

Microbial generalists form planet-wide networks across ecosystems

In a new study published in Cell, scientists in the Bork Group at EMBL Heidelberg reveal that microbes living in similar habitats are more alike than those simply inhabiting the same geographical region.

10 Feb 2026

Type 2 diabetes and hypertension share a genetic link, study shows

Type 2 diabetes and high blood pressure share a genetic link, new research from the University of Surrey, UK and the Université de Lille, France shows.

10 Feb 2026

New genetic model reveals role of keratin 8 in colorectal cancer development

Researchers at Åbo Akademi University have identified a new molecular change in patients with colorectal cancer and developed a genetic disease model that forms tumors in the large intestine, resembling those seen in patients.

10 Feb 2026

Study uncovers how bacterial circadian clocks control gene expression

Our circadian clocks play a crucial role in our health and well-being, keeping our 24-hour biological cycles in sync with light and dark exposure.

10 Feb 2026

New spatial omics platform advances biomedical research in Spain

Spatial omics is a new generation of technologies that allow scientists to study cells in their original location within tissues (without isolating or moving them from their environment).

9 Feb 2026

Chronic brain compression triggers neuron death through multiple pathways

To think, feel, talk and move, neurons send messages through electrical signals in the brain and spinal cord.

9 Feb 2026

Engineered enzyme enables fast and accurate RNA synthesis

From vaccines and diagnostics to emerging gene-based therapies, RNA molecules are now central to modern medicine.

9 Feb 2026

Early life factors crucial for childhood food allergy development

A new study from McMaster University involving 2.8 million children around the world has revealed the most important early-life factors that influence whether a child becomes allergic to food.

9 Feb 2026

Chronic alcohol use profoundly alters gene expression in the brain's reward system

Chronic alcohol consumption profoundly alters gene expression in key brain regions involved in reward, impulse control, and decision-making, according to a study led by researchers at the Institute for Neurosciences, a joint center of Miguel Hernández University of Elche (UMH) and the Spanish National Research Council (CSIC).

9 Feb 2026

Obesity drives shared genetic risk behind many chronic disease combinations

The study uncovers obesity's genetic links to chronic diseases, offering insights into multimorbidity and the potential for targeted health interventions.

9 Feb 2026

CRISPR gene-drive technology reverses antibiotic resistance in bacteria

Antibiotic resistance (AR) has steadily accelerated in recent years to become a global health crisis. As deadly bacteria evolve new ways to elude drug treatments for a variety of illnesses, a growing number of "superbugs" have emerged, ramping up estimates of more than 10 million worldwide deaths per year by 2050.

7 Feb 2026

Blocking p300 restores chemotherapy sensitivity in resistant tumors

Overcoming tumor resistance to chemotherapy drugs has long been a challenge for oncology clinicians and researchers.

6 Feb 2026

New analysis reveals hidden complexity in the vaginal microbiome

For decades, gynecological tests have relied on a simplified view of the vaginal microbiome, categorizing bacteria as either "good" or "bad."

6 Feb 2026

Senescent neutrophils promote tumor survival across cancer types

Renowned as first responders to threatening infections, neutrophils also happen to feature prominently in the microenvironment of tumors, where they and other immune cells play opposing and frequently mutable roles in promoting-or resisting-cancer progression.

6 Feb 2026

New DNA-based vaccine scaffolds boost targeted immune responses to HIV

One of the biggest hurdles in developing an HIV vaccine is coaxing the body to produce the right kind of immune cells and antibodies. In most vaccines, HIV proteins are attached to a larger protein scaffolding that mimics a virus.

6 Feb 2026

Climate change is accelerating antibiotic resistance across the Western Pacific

Urgent action is needed as climate change fuels antibiotic resistance in the Western Pacific, threatening health and highlighting socioeconomic vulnerabilities.

6 Feb 2026