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Study shows immune profile heterogeneity amongst healthy adults

Researchers opted to use single-cell RNA-seq to observe single cells in detail as they encounter a specific antigen.

22 Oct 2021

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Scientists studying the most common and aggressive type of brain tumor in adults have discovered a new way of analyzing diseased and healthy cells from the same patient.

22 Oct 2021

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Scientists at St. Jude Children's Research Hospital have shown that cell-free DNA from cerebrospinal fluid (CSF) can be used to detect measurable residual disease (MRD) in children treated for the brain tumor medulloblastoma.

21 Oct 2021

Researchers use game theory to understand how cells compete in tumors

Game theory applied to cell encounters inside a tumor provides a sociological perspective on the possible behaviors of cells in a collectivity, and offers a more comprehensive understanding of the complex rules that govern a neoplasm.

18 Oct 2021

High levels of cancer-fighting immune cells could indicate a better chance of survival

Cancerous tumors are made up of many more components than just malignant cells from the tissue of origin. Immune cells can be recruited to the tumor site and form what is known as the tumor microenvironment.

18 Oct 2021

Study reveals a link between neuroinflammation protein and survival outcomes in glioblastoma patients

Scientists have discovered a new link that could bring the scientific and medical community closer to understanding why glioblastoma, the most common malignant brain tumor, is deadlier in males than females.

18 Oct 2021

Research group uncovers novel mechanism that regulates breast cancer metastases

A research group at the University of Turku, Finland, has discovered a completely new mechanism that cells use to circulate integrins on the cell surface.

18 Oct 2021

Non-invasive optical probe reveals the complex changes in tumors after immunotherapy

Johns Hopkins University engineers are the first to use a non-invasive optical probe to understand the complex changes in tumors after immunotherapy, a treatment that harnesses the immune system to fight cancer.

13 Oct 2021

Novel therapy approach could stop tumor growth

The immune system protects the body from cancer. To protect healthy body cells from its own immune system, they have developed a protective shield: the protein CD47 is a so called "don't eat me" signal, which tells the immune cells to stand back.

12 Oct 2021

Scientists identify a new method to treat triple-negative breast cancer

A team of clinicians and scientists from the National Cancer Centre Singapore (NCCS), Singapore General Hospital (SGH) and A*STAR's Genome Institute of Singapore (GIS) has identified a novel method to treat triple-negative breast cancer (TNBC). They discovered that cancer cells switch between different cell states and are able to change from being less aggressive ('epithelial') to being more aggressive ('mesenchymal'), and vice versa.

7 Oct 2021

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Pairing a newly developed gel with immunotherapy that was delivered to post-surgical mouse brains with glioblastoma, a highly malignant and deadly cancer, improved the immunotherapy's effectiveness, report researchers from the University of North Carolina Lineberger Comprehensive Cancer Center and colleagues. The findings appeared on Oct. 6, 2021, in Science Advances.

7 Oct 2021

Automated system based on AI helps rule out cancer in women with dense breasts

An automated system that uses artificial intelligence (AI) can quickly and accurately sift through breast MRIs in women with dense breasts to eliminate those without cancer, freeing up radiologists to focus on more complex cases, according to a study published in Radiology.

5 Oct 2021

mRNA vaccination induces strong humoral immune responses against SARS-CoV-2 in over 80's

A recent study assesses the serological and cellular responses to Pfizer’s BNT162b2 mRNA vaccine in people aged 80-96 years.

4 Oct 2021

Long working hours are increasingly causing work-related deaths, global report says

Almost two million people worldwide die of work-related causes, according to joint estimates by the World Health Organization and the International Labour Organization, which cite long working hours, pollution and poor conditions as major factors.

2 Oct 2021

Monoclonal antibodies may reduce hospital stay, but not mortality in COVID-19

A new study explores the real-world efficacy of monoclonal antibodies against COVID-19 in averting severe disease.

27 Sep 2021

New imaging technology for detecting MALT lymphomas could save patients numerous gastroscopies

A new imaging technique for the detection of MALT lymphomas, malignant tumours of the lymphatic system, could probably save patients numerous gastroscopies. A study group of MedUni Wien achieved a high imaging accuracy by way of PET/MR and by using a PET Tracer directed against a certain cell receptor. The results are currently published in the top journal "Blood" of the American Society of Hematology.

24 Sep 2021

New discovery offers clues to overcoming resistance to cancer therapies

Cancer cells proliferate despite a myriad of stresses - from oxygen deprivation to chemotherapy - that would kill any ordinary cell.

23 Sep 2021

New discovery may offer a promising avenue for study of multiple sclerosis

A surprising discovery may offer a promising new direction in the study of multiple sclerosis and other diseases of hypomyelination – when axons of neurons are not covered sufficiently in fatty sheaths (myelin), which disrupts communication between nerve cells.

23 Sep 2021

Sex, age are crucial factors in the care and survival of patients with malignant brain tumors

Findings from a national study by researchers at Translational Genomics Research Institute (TGen), an affiliate of City of Hope, and external collaborators suggest that sex and age are crucial factors in the care and survival of patients with malignant brain tumors and other central nervous systems (CNS) cancers.

23 Sep 2021

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

Cancer-fighting immune cells in patients with lung cancer whose tumors do not respond to immunotherapies appear to be running on a different "program" that makes them less effective than immune cells in patients whose cancers respond to these immune treatments, suggests a new study led by researchers at the Johns Hopkins Kimmel Cancer Center Bloomberg~Kimmel Institute for Cancer Immunotherapy.

22 Sep 2021

Malignant News and Research

Study shows immune profile heterogeneity amongst healthy adults

Researchers find a new way to analyze diseased and healthy cells from brain tumor patients

Cell-free DNA can help detect measurable residual disease in children with medulloblastoma

Researchers use game theory to understand how cells compete in tumors

High levels of cancer-fighting immune cells could indicate a better chance of survival

Study reveals a link between neuroinflammation protein and survival outcomes in glioblastoma patients

Research group uncovers novel mechanism that regulates breast cancer metastases

Non-invasive optical probe reveals the complex changes in tumors after immunotherapy

Novel therapy approach could stop tumor growth

Scientists identify a new method to treat triple-negative breast cancer

Newly developed gel helps improve the effectiveness of immunotherapy in glioblastoma

Automated system based on AI helps rule out cancer in women with dense breasts

mRNA vaccination induces strong humoral immune responses against SARS-CoV-2 in over 80's

Long working hours are increasingly causing work-related deaths, global report says

Monoclonal antibodies may reduce hospital stay, but not mortality in COVID-19

New imaging technology for detecting MALT lymphomas could save patients numerous gastroscopies

New discovery offers clues to overcoming resistance to cancer therapies

New discovery may offer a promising avenue for study of multiple sclerosis

Sex, age are crucial factors in the care and survival of patients with malignant brain tumors

Study findings could lead to novel ways to overcome tumor resistance to immunotherapies

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