Metabolic Disorders News and Research

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$1.7 million grant to advance understanding of genetic influences on diabetes

Scientists at Southwest Foundation for Biomedical Research (SFBR) expect to make big leaps in their understanding of genetic influences on diabetes, thanks to a new $1.7 million grant awarded to Dr. Joanne Curran, the grant's principal investigator.

13 Dec 2007

Umbilical cord blood transplant may confer advantages over bone marrow transplant for kids with life-threatening metabolic disorders

Children born with inherited metabolic disorders that cause organ failure and early death can be treated successfully with umbilical cord blood transplants from unrelated donors and, in some cases go on to live for many years, according to a study led by Duke University Medical Center researchers.

10 Dec 2007

Effects of weight, genetics and religious beliefs on prostate cancer

African-American men face an observable disadvantage versus Caucasian men when it comes to prostate cancer survival.

29 Nov 2007

Binge drinking by adolescents increases long-term risk for heart disease

New research into lifelong alcohol consumption reveals that heavy binge drinking by adolescents and young adults is associated with increased long-term risk for heart disease, high blood pressure, type 2 diabetes, and other metabolic disorders.

21 Nov 2007

Rev-erb protein helps maintain the body's correct metabolism

It's well known that the body's energy levels cycle on a 24-hour, or circadian, schedule, and that this metabolic process is fueled by oxygen.

19 Nov 2007

Hunger influenced by leptin hormone

Researchers at UCLA have determined the brain circuits involved in hunger that are influenced by a hormone called leptin.

29 Oct 2007

Powerful new discovery method speeds up gene discovery

Scientists will be able to pinpoint genetic causes of human diseases faster than ever thanks to a powerful new discovery method unveiled by the Southwest Foundation for Biomedical Research (SFBR) and an international team of researchers.

17 Sep 2007

Zebrafish shed light on human mitochondrial diseases

Zebrafish can now be used to study COX deficiencies in humans, a discovery that gives scientists an unprecedented window to view the earliest stages of mitochondrial impairments that lead to potentially fatal metabolic disorders, according to researchers at the University of Oregon.

13 Sep 2007

Should I increase my vitamin E intake or not?

Conflicting reports about the potential benefits of dietary supplements can make a person's head spin.

11 Sep 2007

Animal model for dengue research

A mosquito-borne disease often known as "break-bone fever" has found a new enemy in a unique type of mouse.

28 Aug 2007

Pfizer and Bristol-Myers Squibb finalize agreement on metabolic disorders program

Pfizer Inc. and Bristol-Myers Squibb Company have announced that they have finalized a definitive agreement for the worldwide collaboration to research, develop and commercialize DGAT-1 inhibitors, a collaboration first announced on April 26, 2007.

28 Aug 2007

New method for early disease diagnosis

Purdue University researchers worked with the Indiana University School of Medicine to establish a technique that provides a new approach for detecting a number of genetic disorders found in infants and young children.

18 Jul 2007

Rimonabant may prevent and treat obesity-related liver disease

A new study on the effect of the anti-obesity drug rimonabant on liver function in obese rats found that it reduced markers of liver damage, decreased levels of pro-inflammatory proteins, and improved lipid profiles.

4 Jul 2007

In mice, drug protects against diabetes and atherosclerosis

Blocking a single protein with an experimental drug prevented and treated both type 2 diabetes and atherosclerosis in laboratory mice that had been fed unhealthy diets and were genetically predisposed to these common killers, according to an article published online in Nature.

8 Jun 2007