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Study explores intratumoral microbiota as a novel frontier in cancer research

Researchers review the role of intratumoral microbiota in cancer development, suggesting its potential in predicting and treating various cancers.

14 Jan 2024

New approach using ultrasound-guided drug delivery effectively targets lymph node metastasis

Researchers at Tohoku University have discovered a new approach for treating lymph node metastasis. Anticancer drugs are administered directly into the LNs under ultrasound guidance (Lymphatic Drug Delivery System or LDDS) to target sentinel lymph nodes (LNs) and generate antitumor effects locally, preventing distant metastasis.

12 Jan 2024

Study sheds light on how impaired autophagy can play a role in causing heart failure

A new study sheds light on how autophagy, the body's process for removing damaged cell parts, when impaired, can play a role in causing heart failure.

11 Jan 2024

Glioblastoma tumor cells mimic neurons to evade treatment

Certain cancers are more difficult to treat because they contain cells that are highly skilled at evading drugs or our immune systems by disguising themselves as healthy cells.

11 Jan 2024

mRNA therapy shows promise for curing children's rare liver disease

By exploiting the technology used in Covid-19 vaccines, a team led by UCL, King's College London and Moderna scientists has created an effective therapy for a rare disease, in a study in mice, demonstrating the technology's potential therapeutic use in people.

10 Jan 2024

Blocking brain inflammation could slow, reverse ALS symptoms

In people with amyotrophic lateral sclerosis (ALS), changes in neurons appear to activate immune cells. Lowering the inflammation could reduce the symptoms of the disease, according to a study led by Chantelle Sephton, a professor at Université Laval's Faculty of Medicine.

10 Jan 2024

MedUni Vienna researchers discover possible trigger of chronic inflammatory bowel disease

As the cause of chronic inflammatory bowel diseases (IBD) such as Crohn's disease or ulcerative colitis is not yet known, treatment for sufferers is currently aimed at alleviating the often agonizing symptoms.

10 Jan 2024

First-of-its-kind research shines light on how certain pathogens can outwit the body's immune system

In a first-of-its-kind research breakthrough, a team of scientists at the University of Massachusetts Amherst has analyzed and described what they call the "mosquito effect," which sheds light on how certain pathogens, such as cancerous tumor cells, can outwit the body's immune system.

8 Jan 2024

Three cytokine pairs found to be responsible for the body's damaging response to sepsis

Sepsis - when an infection causes the immune system to improperly target the body - is one of the leading causes of death in the ICU.

8 Jan 2024

Revolutionary study reveals Lactobacillus acidophilus could ward off liver cancer linked to fatty liver disease

Probiotic supplementation with Lactobacillus acidophilus could help prevent non-alcoholic fatty liver disease.

8 Jan 2024

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Researchers at the University of Michigan Health Rogel Cancer Center have identified a mechanism that causes severe gastrointestinal problems with immune-based cancer treatment.

5 Jan 2024

Inhalable point-of-care urinary diagnostic platform for early lung cancer detection

Using a new technology developed at MIT, diagnosing lung cancer could become as easy as inhaling nanoparticle sensors and then taking a urine test that reveals whether a tumor is present.

5 Jan 2024

New study brings us closer to growing replacement lungs for patients

Chronic obstructive pulmonary disease (COPD) is the third leading cause of death worldwide. It is marked by lung damage that is lasting and incurable, leaving lung transplantation as the only viable treatment option.

5 Jan 2024

Unlocking the power of diet: How miRNAs influence health and disease

The role of dietary microRNAs (miRNAs) in health and disease.

5 Jan 2024

Salk scientists map brain circuit triggering the crippling panic attacks

Overwhelming fear, sweaty palms, shortness of breath, rapid heart rate - these are the symptoms of a panic attack, which people with panic disorder have frequently and unexpectedly.

4 Jan 2024

Simple technique boosts antibody delivery for treating brain diseases

The blood-brain barrier blocks the entry of antibodies into the brain. This limits the potential use of antibody therapeutics to treat brain diseases, such as brain tumors.

3 Jan 2024

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

New research has identified the specific biological mechanism behind the muscle dysfunction found in myotonic dystrophy type 1 (DM1) and further shows that calcium channel blockers can reverse these symptoms in animal models of the disease.

2 Jan 2024

Study points to senolytic drugs as potential weapon against lung emphysema

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 23, entitled, "Benidipine calcium channel blocker promotes the death of cigarette smoke-induced senescent cells and improves lung emphysema."

20 Dec 2023

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

A Nature journal study employs deep learning to analyze chemical sub-structures, leading to the discovery of new structural classes of antibiotics, showcasing the potential of AI in accelerating antibiotic development.

20 Dec 2023

UCL scientists receive £997,000 from the Type 1 Diabetes Grand Challenge

Scientists at the UCL Institute of Immunity & Transplantation (IIT) are part of a team to receive £997,000 from the Type 1 Diabetes Grand Challenge, a new partnership involving The Steve Morgan Foundation, Diabetes UK and JDRF.

19 Dec 2023

Mouse Model News and Research

Study explores intratumoral microbiota as a novel frontier in cancer research

New approach using ultrasound-guided drug delivery effectively targets lymph node metastasis

Study sheds light on how impaired autophagy can play a role in causing heart failure

Glioblastoma tumor cells mimic neurons to evade treatment

mRNA therapy shows promise for curing children's rare liver disease

Blocking brain inflammation could slow, reverse ALS symptoms

MedUni Vienna researchers discover possible trigger of chronic inflammatory bowel disease

First-of-its-kind research shines light on how certain pathogens can outwit the body's immune system

Three cytokine pairs found to be responsible for the body's damaging response to sepsis

Revolutionary study reveals Lactobacillus acidophilus could ward off liver cancer linked to fatty liver disease

Researchers identify mechanism that causes gastrointestinal problems with cancer immunotherapy

Inhalable point-of-care urinary diagnostic platform for early lung cancer detection

New study brings us closer to growing replacement lungs for patients

Unlocking the power of diet: How miRNAs influence health and disease

Salk scientists map brain circuit triggering the crippling panic attacks

Simple technique boosts antibody delivery for treating brain diseases

Calcium channel blockers reverse muscle weakness in animal model of myotonic dystrophy type 1

Study points to senolytic drugs as potential weapon against lung emphysema

Deep learning unlocks new antibiotic classes, revolutionizing the fight against resistance

UCL scientists receive £997,000 from the Type 1 Diabetes Grand Challenge

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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