Nephropathy News and Research

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Nephropathy is a broad medical term used to denote disease or damage of the kidney, which can eventually result in kidney failure. The primary and most obvious functions of the kidney are to excrete any waste products and to regulate the water and acid-base balance of the body – therefore loss of kidney function is a potentially fatal condition.

Study shows chronic exposure to cadmium may cause liver disease

People with higher levels of cadmium in their urine — evidence of chronic exposure to the heavy metal found in industrial emissions and tobacco smoke — appear to be nearly 3.5 times more likely to die of liver disease than those with lower levels, according to a study by Johns Hopkins scientists.

10 May 2013

Children on dialysis for severe kidney disease have reduce risk of death

Children on dialysis for severe kidney disease have a dramatically reduced risk of death compared to 20 years ago, a new study shows. The findings, from a study led by Dr. Bethany Foster from the Research Institute of the McGill University Health Centre (RI-MUHC), are very encouraging for children with end-stage kidney disease.

10 May 2013

Lexicon Pharmaceuticals advances Phase 2 clinical trial of LX4211 in patients with type 1 diabetes

Lexicon Pharmaceuticals, Inc. announced today that it is progressing into the placebo-controlled portion of its Phase 2 clinical trial of LX4211 in patients with type 1 diabetes, having successfully completed the open-label, pioneer portion of the trial.

10 May 2013

Study finds decrease in mortality rates among children initiating ESKD treatment with dialysis

In a study that included more than 20,000 patients, there was a significant decrease in the United States in mortality rates over time among children and adolescents initiating end-stage kidney disease treatment with dialysis between 1990 and 2010, according to a study in the May 8 issue of JAMA.

5 May 2013

Higher vitamin D levels confer no additional benefit

In recent years, healthy people have been bombarded by stories in the media and on health websites warning about the dangers of too-low vitamin D levels, and urging high doses of supplements to protect against everything from hypertension to hardening of the arteries to diabetes.

2 May 2013

AMGA, AMGF unveil two major resources to improve high blood pressure control

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2 May 2013

New collaboration provides access, allows users to make decisions based on data

Archimedes, Inc., a healthcare modeling and analytics company, announced today that it has begun collaborating with the United States Department of Health and Human Services and Centers for Medicare & Medicaid Services to provide unprecedented access to synthetic CMS claims data.

2 May 2013

Organic pollutants increase nephropathy risk in diabetes

Individuals with diabetes may reduce their risk for developing nephropathy if they minimize their exposure to persistent organic pollutants, suggest researchers.

29 Apr 2013

Laparoscopic radical nephropathy effective for advanced renal masses

Laparoscopic radical nephrectomy is an effective treatment approach for individuals with renal cell carcinoma who have larger or more advanced renal masses, report researchers.

29 Apr 2013

Kidney disease screening needs rethink in hypertension

The standard approach to detecting chronic kidney disease fails to spot the condition in about a quarter of patients with hypertension, a study suggests.

29 Apr 2013

Nephropathy risk lowered by glucose, BP control in Type 1 diabetes

Individuals with Type 1 diabetes should keep good control of their blood sugar levels and blood pressure to reduce their risk for developing nephropathy, say researchers.

29 Apr 2013

UK’s health performance: an interview with Prof. Murray, University of Washington

Rates of premature mortality in the UK have been falling steadily, but the pace of decline is not as fast as in many other high-income countries, such as Australia. In that sense, the UK lags behind.

29 Apr 2013

New clinical algorithm to treat complex pediatric patients with ARPKD

A collaborative team of physician-scientists at the Medical College of Wisconsin and Children's Hospital of Wisconsin Research Institute has developed a new evidence-based, clinical algorithm to help physicians treat complex patients with autosomal recessive polycystic kidney disease.

29 Apr 2013

Practical guidelines on the use of new oral anticoagulants

A practical guide on the use of the new oral anticoagulants has been produced by the European Heart Rhythm Association of the European Society of Cardiology.

29 Apr 2013

Renal denervation reduces blood pressure for patients not responding to drug therapy

Up to 10 per cent of patients with high blood pressure are resistant to treatment, which puts them at increased risk of cardiovascular events, including heart attacks. Clinical trials show that catheter-based renal denervation reduces blood pressure in patients who do not respond to conventional drug therapy.

26 Apr 2013

Combinations of sEH inhibition and PPARγ activation have beneficial effects on cardiometabolic syndrome

Scientists at the Medical College of Wisconsin and the University of California at Davis, led by Dr. John Imig and Dr. Bruce Hammock have determined the synergistic actions of inhibiting soluble epoxide hydrolase (sEH) with tAUCB (trans-4-(4-[3-adamantan-1-yl-ureid]-cyclohexyloxy)-benzoic acid) and activating peroxisome proliferator-activator receptorγ (PPARγ) with the thiazolidinedione rosiglitazone on the pathological progression of cardiometabolic syndrome.

25 Apr 2013

Nanogels to attack lupus: an interview with Dr Look and Dr Fahmy, Yale University

Nanogels are synthetic particles that can be used for drug delivery. They are approximately 100 nm to 200 nm in diameter, and are made from safe, biocompatible materials: a gel-like interior and a lipid exterior.

24 Apr 2013

Drug that targets phosphate does not improve CVD measures in patients with mild kidney disease

High phosphate levels in the blood carry increased heart-related risks, but taking a drug that targets phosphate does not improve cardiovascular measures in patients with mild kidney disease, according to a study appearing in an upcoming issue of the Journal of the American Society of Nephrology (JASN).

19 Apr 2013

Study: Mediterranean diet associated with lower risk of hyperuricemia in older adults

According to a study published in the Journals of Gerontology Series A: Biological Sciences and Medical Sciences, a baseline adherence to a Mediterranean diet (MeDiet) is associated with a lower risk of hyperuricemia, defined as a serum uric acid (SUA) concentration higher than 7mg/dl in men and higher than 6mg/dl in women.

19 Apr 2013

New health MOT-style programme likely to uncover more diabetes, kidney or heart patients

University of Leicester researchers have found that the NHS Health Check Programme is likely to find 440,000 people each year who have diabetes or chronic kidney disease or who are at high risk of cardiovascular disease or diabetes.

19 Apr 2013

Nephropathy News and Research

Further Reading

Study shows chronic exposure to cadmium may cause liver disease

Children on dialysis for severe kidney disease have reduce risk of death

Lexicon Pharmaceuticals advances Phase 2 clinical trial of LX4211 in patients with type 1 diabetes

Study finds decrease in mortality rates among children initiating ESKD treatment with dialysis

Higher vitamin D levels confer no additional benefit

AMGA, AMGF unveil two major resources to improve high blood pressure control

New collaboration provides access, allows users to make decisions based on data

Organic pollutants increase nephropathy risk in diabetes

Laparoscopic radical nephropathy effective for advanced renal masses

Kidney disease screening needs rethink in hypertension

Nephropathy risk lowered by glucose, BP control in Type 1 diabetes

UK’s health performance: an interview with Prof. Murray, University of Washington

New clinical algorithm to treat complex pediatric patients with ARPKD

Practical guidelines on the use of new oral anticoagulants

Renal denervation reduces blood pressure for patients not responding to drug therapy

Combinations of sEH inhibition and PPARγ activation have beneficial effects on cardiometabolic syndrome

Nanogels to attack lupus: an interview with Dr Look and Dr Fahmy, Yale University

Drug that targets phosphate does not improve CVD measures in patients with mild kidney disease

Study: Mediterranean diet associated with lower risk of hyperuricemia in older adults

New health MOT-style programme likely to uncover more diabetes, kidney or heart patients

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