Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

New research center will pave way to better diagnosis and treatment of skin diseases

The new LEO Foundation Skin Immunology Research Center at the University of Copenhagen will pave the way to a better understanding, prevention and treatment of skin diseases that plague a quarter of the world's population.

19 Nov 2018

Study shows how pneumococci challenge the immune system

Pneumococci are the most common cause of respiratory tract infections, such as otitis and sinusitis, as well as of severe infections like pneumonia and meningitis.

12 Nov 2018

Scientists move closer to gonorrhea vaccine after large-scale proteomic study

In a study of proteins historic in its scope, researchers at Oregon State University have pushed closer both to a vaccine for gonorrhea and toward understanding why the bacteria that cause the disease are so good at fending off antimicrobial drugs.

8 Nov 2018

CNIO researchers link MASTL protein to origin of thrombocytopenia

The Cell Division and Cancer Group of the Spanish National Cancer Research Centre has discovered that MASTL, the protein whose function in the organism has not yet been sufficiently investigated, plays an important role in controlling the cytoskeleton, the structure that gives shape to the cells, and enables their mobility and capacity for grouping.

1 Nov 2018

Researchers deconstruct royal jelly that determines honeybee hierarchy

Katharina Paschinger's father, a conservation chemist in Vienna, was a devoted beekeeper. Paschinger remembers fondly that he would bring royal jelly, an important food for bee larvae, as a gift on visits to her maternal grandmother.

30 Oct 2018

Scientists find ways to block nitration of amino acids to improve cancer immunotherapy

Immunotherapy -- harnessing T-cells to attack cancer cells in the body -- has given hope to patients who endure round after round of treatment, including chemotherapy, to little effect. For all of its promise, however, immunotherapy still benefits only a minority of patients -- a reality driving research in the field for ways to improve the relatively new approach.

30 Oct 2018

Researchers track where tetracycline antibiotics go in human cells

We know that antibiotics treat bacterial infections. We also know why they work. Tetracycline antibiotics, for example, stop bacteria from making protein. Like a boot on a wheel, the drugs bind to the bacterial cell's ribosome--where protein is made--and prevent it from working. Without protein, the bacteria weaken and die.

25 Oct 2018

New approach may lead to better diagnostic techniques for autoimmune disorders

If we really want to know how our body's cells work - or don't work, in the case of disease - we might need to look beyond their genes and even beyond the proteins they are made of.

23 Oct 2018

Newly discovered toxin stands out from others in the battle for microbial domination

A newly discovered toxin that some bacteria deploy to fend off competing bacteria stands out from others in the battle for microbial domination. While many deadly substances have been identified among bacteria, this previously unknown toxin behaves in a familiar way.

19 Oct 2018

New findings reveal potential cellular players in tumor microenvironment

New findings presented today by CytoReason reveals possible new cellular players in the tumor microenvironment that could impact the treatment process for the most in-need patients - those who have already failed to respond to ipilimumab (anti-CTLA4) immunotherapy.

16 Oct 2018

Metabolome tests could be new way to measure obesity and health

The link between obesity and health problems may seem apparent. People who are obese are at higher risk of type 2 diabetes, liver disease, cancer, and heart disease.

12 Oct 2018

Researchers uncover how common pain reliever causes liver failure

Acetaminophen is a common pain reliever found in every pharmacy. However, it is also the No. 1 cause of acute liver failure in the United States. In the liver, acetaminophen is converted into a new compound that covalently binds to proteins at an amino acid called cysteine.

11 Oct 2018

Bridge-like structure within estrogen receptor could serve as new drug target for breast cancer

Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis.

10 Oct 2018

Seed oils are best choice for improving cholesterol

If you want to lower your low-density lipoprotein cholesterol, called LDL or, colloquially, "bad cholesterol," the research is clear about one thing: You should exchange saturated fats with unsaturated fat. If you want to know what you should use to sauté your dinner, that's a harder question to answer. Many of the studies establishing that mono- and polyunsaturated fats are better for blood lipids than saturated fats swapped out one food source at a time, making it hard to tell which of a plethora of vegetable oils might be most beneficial.

9 Oct 2018

A Single Platform to Sequence All Monoclonal Antibody Proteins

Having a single platform to sequence all monoclonal antibody proteins provides researchers with key information for research, development and drug discovery

From Rapid Novor Inc 3 Oct 2018

Scientists investigate effect of flu-causing virus on three lung-derived cell lines

Perhaps inspired by the annual 3 to 5 million cases of severe influenza worldwide, the Guinness World Record organization is advertising for individuals or organizations to attempt a record for the most people getting a flu awareness lesson at once.

29 Sep 2018

Researchers design new combination therapy for reducing NSCLC cell growth

Lung cancer is the leading cause of cancer death among men and women. About 85 percent of lung cancers are non-small cell lung cancer. For a handful of these patients, therapies that target specific genetic mutations are effective.

29 Sep 2018

UNIST to accelerate discovery, development of new medicines for incurable diseases

On August 23, UNIST held a grand opening ceremony of Cellular Responses to Metabolic Stress Research Center in a bid to accelerate the discovery and development of breakthrough medicines for diseases thought to be incurable.

18 Sep 2018

New research on sperm quality updates advice for couples trying to conceive

Could doctors at fertility clinics be giving men bad advice? Dr. Da Li and Dr. XiuXia Wang, who are clinician-researchers at the Center for Reproductive Medicine of Shengjing Hospital in Shenyang in northeast China, think so.

17 Sep 2018

New studies examine links between fatty liver disease and mitochondrial dysfunction

Researchers at Northeast Ohio Medical University studied the lifespan of mitochondrial proteins in a mouse model of fatty liver disease. Comparing the amount of protein between healthy mice and a mouse model of nonalcoholic fatty liver disease gave them an estimate of each protein's half-life.

17 Sep 2018