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Detecting rare blood clots was a win, but US vaccine safety system still has gaps

The quick detection of an ultra-rare blood clotting reaction in some Covid-19 vaccine recipients showed the power of a federal warning system for vaccine safety issues, but experts worry that blind spots in the program could hamper detection of other unexpected side effects.

3 May 2021

CVS and Walgreens have wasted more vaccine doses than most states combined

Two national pharmacy chains that the federal government entrusted to inoculate people against Covid-19 account for the lion's share of wasted vaccine doses, according to government data obtained by KHN.

3 May 2021

As vaccine demand slows, political differences go on display in California Counties

Demand for Covid vaccines is slowing across most of California, but as traffic at vaccination sites eases, the vaccination rates across the state are showing wide disparities.

3 May 2021

A new SARS-CoV-2 variant (HMN.19B) has been identified in France

New research published in the Centers for Disease Control and Prevention’s journal Emerging Infectious Diseases has confirmed the emergence of a new SARS-CoV-2 variant called HMN.19B from the viral clade 19B in France. The 19B viral clade — which includes the D614G variant — was prevalent in late 2019 but had since been rarely observed since early 2020 because of newer viral clades.

3 May 2021

Vaccine candidate targeting SARS-CoV-2 nucleocapsid protein elicits protective immune response in animal model

New preclinical results from a study led by David Masopust of the University of Minnesota in Minneapolis, USA, show that a Had5-based vaccine targeting the nucleocapsid protein can also elicit a protective immune response.

3 May 2021

Competitive multiplex binding assay can monitor SARS-CoV-2 immune responses using nanobodies

Researchers at the Eberhard Karls University and the University of Tübingen in Germany described 11 unique nanobodies (Nbs) specific for the SARS-CoV-2 spike receptor-binding domain (RBD), of which 8 Nbs potentially inhibit the connection of RBD with the angiotensin-converting enzyme 2 (ACE2).

3 May 2021

Study finds one-third of COVID-19 patients experience neurological symptoms

The research on the short and long-term effects of COVID-19 disease is ongoing. Still, scientists have found severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) affects the brain causing loss of smell and taste, dizziness, muscle pain, fatigue, and other cognitive impairments. However, it remained unknown why certain people developed neurological symptoms while others did not.

3 May 2021

Study estimates true number of COVID-19 deaths by U.S. county

Every country has been affected by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that has spawned a pandemic. For several factors, the United States has been hit hard by the number of coronavirus cases and death. The country currently leads the world with over 32.4 million infections and more than 577,000 COVID-19 deaths.

3 May 2021

Study reveals new broadly neutralizing and protective antibody against coronaviruses

In the setting of potentially reduced vaccine efficacy against coronavirus disease (COVID-19) due to emerging viral variants, the deployment of effective treatments based on monoclonal antibodies may be an additional strategy to help control the pandemic. A new study by US researchers, currently available on the bioRxiv* preprint server, describes the action of a specific antibody known as DH1047.

3 May 2021

Researchers identify novel SARS-CoV-2 variant with mutations in membrane protein-encoding gene

A recent study published in the Journal Emerging Microbes and Infections has highlighted the emergence of a novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant with mutations in the membrane protein-encoding gene. Two potential mutations, M:I82T and M:V70L, have been identified within the transmembrane helices, which are expected to improve viral fitness by modulating glucose uptake during replication.

3 May 2021

Researchers develop a nanoparticle-based formulation with anti-SARS-CoV-2 activity

A study recently published in the journal Matter has demonstrated the development and validation of a nanoparticle-based formulation, capable of completely inhibiting the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection blocking the interaction between viral spike protein and host cell angiotensin-converting enzyme 2 (ACE2).

3 May 2021

Study implies a likely rise of future SARS-CoV-2 recombinants

A recent astonishing feat by US researchers revealed that recombination is not only widespread in the evolutionary history of SARS-like coronaviruses, but it can also increase fitness traits of seasonal coronaviruses. Their paper is currently available on the bioRxiv* preprint server and sets the stage for phylogenetic tracking of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2).

2 May 2021

Live "attenuated" influenza virus vaccine protects animals against respiratory infections, including SARS-CoV-2

Researchers in the United States and Austria have demonstrated the potential of a modified influenza virus as a vaccine to protect against viral respiratory pathogens, including the novel severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes coronavirus disease 2019 (COVID-19).

2 May 2021

Previously infected vaccinees broadly neutralize SARS-CoV-2 variants of concern

Researchers in the United States have conducted a study demonstrating the effectiveness of first-generation vaccines at protecting against variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) in individuals who have previously been infected with the virus.

2 May 2021

The Lancet study: Minority ethnic groups in the UK at increased risk for poor COVID-19 outcomes

Minority ethnic groups had higher risk of testing positive for SARS-CoV-2 and of COVID-19-related hospitalizations, intensive care (ICU) admissions and death compared with white groups in England, according to an observational study published in The Lancet.

30 Apr 2021

Vaccines can save lives and safeguard health and well-being

Effectively and safely protecting against disease--this is what makes vaccines a vital and successful public health tool that saves lives and safeguards health and well-being. Today, vaccines shield us from more than 20 life-threatening diseases.

30 Apr 2021

Single dose of vaccine boosts protection only in people previously infected by COVID-19

A single dose of vaccine boosts protection against SARS-CoV-2 coronavirus variants, but only in those with previous COVID-19, a study has found.

30 Apr 2021

Applications of nanoparticles in combating COVID-19

Researchers review the various properties and use of nanoparticles in targeting SARS-CoV-2 and how they could be used to develop new therapeutics and diagnostics for SARS-CoV-2.

30 Apr 2021

Furin cleavage site crucial in SARS-CoV-2 for viral transmission in ferrets, finds study

Researchers based at Imperial College London, UK, have recently highlighted the effects of these deleterious CS mutations through a ferret animal model, demonstrating that furin cleavage sites are a necessary component in the virus’ ability to replicate.

30 Apr 2021

Despite all the talk, Covid vaccination does not infect people with shingles

Posts are showing up all over social media tying Covid-19 vaccinations to shingles and other painful skin disorders.

30 Apr 2021

Coronavirus News and Research

Detecting rare blood clots was a win, but US vaccine safety system still has gaps

CVS and Walgreens have wasted more vaccine doses than most states combined

As vaccine demand slows, political differences go on display in California Counties

A new SARS-CoV-2 variant (HMN.19B) has been identified in France

Vaccine candidate targeting SARS-CoV-2 nucleocapsid protein elicits protective immune response in animal model

Competitive multiplex binding assay can monitor SARS-CoV-2 immune responses using nanobodies

Study finds one-third of COVID-19 patients experience neurological symptoms

Study estimates true number of COVID-19 deaths by U.S. county

Study reveals new broadly neutralizing and protective antibody against coronaviruses

Researchers identify novel SARS-CoV-2 variant with mutations in membrane protein-encoding gene

Researchers develop a nanoparticle-based formulation with anti-SARS-CoV-2 activity

Study implies a likely rise of future SARS-CoV-2 recombinants

Live "attenuated" influenza virus vaccine protects animals against respiratory infections, including SARS-CoV-2

Previously infected vaccinees broadly neutralize SARS-CoV-2 variants of concern

The Lancet study: Minority ethnic groups in the UK at increased risk for poor COVID-19 outcomes

Vaccines can save lives and safeguard health and well-being

Single dose of vaccine boosts protection only in people previously infected by COVID-19

Applications of nanoparticles in combating COVID-19

Furin cleavage site crucial in SARS-CoV-2 for viral transmission in ferrets, finds study

Despite all the talk, Covid vaccination does not infect people with shingles

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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