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Study reveals new way to inhibit capillary leakage in sepsis

Leakage from the blood capillaries is a key mechanism leading to septic shock and multiorgan failure, which affect millions of patients annually worldwide. However, there is no effective way to inhibit the vessel leakiness. A new study by scientists at the University of Helsinki and Wihuri Research Institute demonstrates that vascular leakage can be inhibited by targeting vascular integrins.

25 Jun 2018

FDA approves new marijuana-based drug to treat rare and severe forms of epilepsy

The U.S. Food and Drug Administration today approved Epidiolex (cannabidiol) oral solution for the treatment of seizures associated with two rare and severe forms of epilepsy, Lennox-Gastaut syndrome and Dravet syndrome, in patients two years of age and older.

25 Jun 2018

Testosterone levels in men largely determined by their childhood environment

Men's testosterone levels are largely determined by their environment during childhood, according to new research.

25 Jun 2018

Otago researchers shed light on neglected problem of typhoid fever in the Pacific

University of Otago researchers have been key partners in a study which has found poor sanitation facilities appear to be a major source of Salmonella Typhi, the cause of typhoid fever, in Fiji.

25 Jun 2018

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

AbbVie , a research-based global biopharmaceutical company, and Calibr, a nonprofit drug discovery division of Scripps Research, today announced a collaboration to develop T-cell therapies aimed primarily at cancer, including solid tumors.

25 Jun 2018

Study examines link between gestational age at birth and ADHD symptoms in children

Early premature birth at less than 34 weeks was associated with symptoms of attention-deficit/hyperactivity disorder in preschool-age children and inattention symptoms in school-age children.

25 Jun 2018

Cholera transmission tracked at household level across Dhaka

For the first time, the transmission of cholera has been tracked at the household level across Dhaka, Bangladesh, a city with a 'hyper-endemic' level of the disease.

25 Jun 2018

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

A tumor's goal is simple: to grow, grow, grow, by making more cancer cells. But that often means growing so fast that the oxygen supply gets scarce, at which point cells within the tumor start to suffocate.

25 Jun 2018

Researchers discover immune profile for effective cancer immunotherapy

In a new study published online June 25, 2018 in Nature Medicine, UC San Francisco researchers have identified a key biological pathway in human cancer patients that appears to prime the immune system for a successful response to immunotherapy drugs known as checkpoint inhibitors.

25 Jun 2018

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Chemical compounds produced by the bacteria in our gut could be used to spot the early stages of liver disease, according to new research.

25 Jun 2018

Researchers work on new treatment that could improve lives of cystic fibrosis patients

Researchers at Oregon State University and Oregon Health & Science University are working on a treatment that holds great promise for improving the lives of cystic fibrosis patients.

25 Jun 2018

New discovery suggests potential target for treating cancers and other diseases

When cells grow and divide to ensure a biological function - such as a properly working organ - DNA must be unwound from its typical tightly packed form and copied into RNA to create proteins.

25 Jun 2018

Eye could be a surrogate for brain degeneration like AD

Researchers from Queen's University Belfast have shown for the first time that the eye could be a surrogate for brain degeneration like Alzheimer's disease (AD).

25 Jun 2018

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Researchers at the Johns Hopkins Kimmel Cancer Center and the Bloomberg~Kimmel Institute for Cancer Immunotherapy released a study investigating the use of combination checkpoint immunotherapy in the treatment of a lethal form of advanced prostate cancer.

25 Jun 2018

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Cedars-Sinai has launched an initiative to accelerate the development of novel drugs, devices and therapies aimed at improving treatments for patients with gastrointestinal and metabolic diseases.

25 Jun 2018

Children with pre-existing allergies should be screened for eosinophilic esophagitis

Children with known skin, food and respiratory allergies should be screened for an emerging, chronic food allergy called eosinophilic esophagitis, a painful inflammation of the esophagus, the food tube between the mouth and stomach.

25 Jun 2018

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

Merck, known as MSD outside the United States and Canada, today announced that the U.S. Food and Drug Administration has accepted for standard review a new supplemental Biologics License Application for KEYTRUDA, Merck's anti-PD-1 therapy, as adjuvant therapy in the treatment of patients with resected, high-risk stage III melanoma and granted a Prescription Drug User Fee Act, or target action, date of February 16, 2019.

25 Jun 2018

Research News and Research

Study reveals new way to inhibit capillary leakage in sepsis

FDA approves new marijuana-based drug to treat rare and severe forms of epilepsy

Testosterone levels in men largely determined by their childhood environment

Otago researchers shed light on neglected problem of typhoid fever in the Pacific

AbbVie and Calibr collaborate to develop T-cell therapies aimed at cancer

Study examines link between gestational age at birth and ADHD symptoms in children

Cholera transmission tracked at household level across Dhaka

Oxygen-starved tumors have an Achilles' heel that could be targeted with drugs

Researchers discover immune profile for effective cancer immunotherapy

Chemical compounds produced by gut bacteria could help spot early stages of liver disease

Researchers work on new treatment that could improve lives of cystic fibrosis patients

New discovery suggests potential target for treating cancers and other diseases

Eye could be a surrogate for brain degeneration like AD

Genetic subset of prostate cancer may benefit from combination checkpoint immunotherapy

Cedars-Sinai launches new initiative to improve treatments for gastrointestinal, metabolic diseases

Children with pre-existing allergies should be screened for eosinophilic esophagitis

Merck announces FDA acceptance of supplemental Biologics License Application for KEYTRUDA

New tests accurately detect heart disease and adverse cardiac events in diabetic patients

Researchers review ethical issues in authentication of patients in medicine using online system

Study links molecular changes in the brain to key behaviors in addiction

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

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