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Researchers unveil comprehensive portrait of the genome of world's first immortal cell line

A team from the University of Washington has unveiled a comprehensive portrait of the genome of the world's first immortal cell line, known as HeLa. The cell line was derived in 1951 from an aggressive cervical cancer that killed Henrietta Lacks, a 31-year-old African-American tobacco farmer and mother of five - the subject of the 2010 New York Times bestseller, The Immortal Life of Henrietta Lacks.

8 Aug 2013

Brain tumor cells in arrested development contribute to cell variety that protects cancer

A program that pushes immature cells to grow up and fulfill their destiny as useful, dedicated cells is short-circuited in the most common and deadly form of brain tumor, scientists at The University of Texas MD Anderson Cancer Center report this week in the Early Edition of the Proceedings of the National Academy of Sciences.

8 Aug 2013

DNA mutation 'signature' identified in urinary tract cancers linked to birthwort herb

Genomic sequencing experts at Johns Hopkins partnered with pharmacologists at Stony Brook University to reveal a striking mutational signature of upper urinary tract cancers caused by aristolochic acid, a plant compound contained in herbal remedies used for thousands of years to treat a variety of ailments such as arthritis, gout and inflammation.

8 Aug 2013

Cancer-linked mitosis: an interview with Professor Scott Kern, Johns Hopkins University School of Medicine

Mitosis is the process by which a cell gives rise to two daughter cells. It’s the basis behind the growth of the human body, the renewal of the human body as it ages, and unfortunately, the growth of cancers.

7 Aug 2013

Roche releases new software for accurate sequencing of long 16S ribosomal RNA amplicons

Roche announced today the global launch of a new software update that significantly extends the range of amplicon lengths available for targeted next-generation sequencing studies on the 454 GS FLX+ System.

7 Aug 2013

Findings may allow lower doses of chemotherapy, limit toxic side effects

In research recently published in Nature Structural & Molecular Biology, Alessandro Vindigni, Ph.D., associate professor of biochemistry and molecular biology at Saint Louis University, discovered how cancer cells respond to the damage caused by an important class of anti-cancer drugs, topoisomerase I inhibitors.

7 Aug 2013

TGen receives $20,000 grant from ACF for STEM education

The Translational Genomics Research Institute (TGen) received another boost today for Science, Technology, Engineering and Math (STEM) education with a $20,000 grant from the Arizona Community Foundation (ACF).

7 Aug 2013

Study examines genetic overlap between Parkinson disease and Alzheimer disease

A study by Valentina Moskvina, Ph.D., of the Cardiff University School of Medicine, Wales, United Kingdom, and colleagues, examined the genetic overlap between Parkinson disease and Alzheimer disease.

6 Aug 2013

Study reveals nearly 40% of tumors are caused by viruses

The results of a large-scale analysis of the association between DNA viruses and human malignancies suggest that many of the most common cancers are not associated with DNA viruses.

6 Aug 2013

New England Biolabs Gains Access To Advanced NGS Library Prep Method

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From New England Biolabs 6 Aug 2013

Affymetrix introduces new OncoScan FFPE Assay Kit

Affymetrix, Inc. announced the launch of the new OncoScan™ FFPE Assay Kit, a whole-genome copy number assay for highly degraded FFPE solid tumor samples, at the Cancer Cytogenomics Microarray Consortium conference being held in Chicago this week.

5 Aug 2013

Study opens door to possible treatments for variety of mitochondrial diseases

By borrowing a tool from bacteria that infect plants, scientists have developed a new approach to eliminate mutated DNA inside mitochondria-the energy factories within cells. Doctors might someday use the approach to treat a variety of mitochondrial diseases, including the degenerative eye disease Leber hereditary optic neuropathy. The research, published online today in Nature Medicine, was funded by the National Eye Institute, a part of the National Institutes of Health.

5 Aug 2013

New research may influence development of anti-viral therapies to fight against Dengue

New research into the fight against Dengue, an insect-borne tropical disease that infects up to 390 million people worldwide annually, may influence the development of anti-viral therapies that are effective against all four types of the virus.

3 Aug 2013

NanoString announces Early Access Program for nCounter Elements used in translational research

NanoString Technologies, Inc. (NASDAQ: NSTG), a provider of life science tools for translational research and molecular diagnostic products, today announced an Early Access Program for nCounter Elements™, a line of General Purpose Reagents (GPRs) developed specifically to meet the needs of translational research and clinical laboratories.

From NanoString Technologies 2 Aug 2013

Wild type genetic background affects outcomes of interactions between genetic mutations

In the current issue of PLOS Genetics, Michigan State University genetic scientists have begun to understand how the rest of the genome interacts with such mutations to cause the differences we see among individuals.

2 Aug 2013

Study offers new hope for treatment of diffuse large B-cell lymphoma

Researchers have discovered how an experimental drug is capable of completely eradicating human lymphoma in mice after just five doses. The study, led by researchers at Weill Cornell Medical College, sets the stage for testing the drug in clinical trials of diffuse large B-cell lymphoma, the most common subtype of non-Hodgkin lymphoma, itself the seventh most frequently diagnosed cancer in the U.S.

2 Aug 2013

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

The most commonly diagnosed form of breast cancer, termed estrogen receptor positive or ER+, accounts for the largest percentage of breast cancer deaths each year. Research by scientists at the HudsonAlpha Institute for Biotechnology and the University of Alabama at Birmingham Comprehensive Cancer Center aims to provide physicians a more targeted approach to treating ER+ breast cancer.

2 Aug 2013

Study proposes novel approach for understanding how genome affects biology of the human body

Recent technological developments in genomics have revealed a large number of genetic influences on common complex diseases, such as diabetes, asthma, cancer or schizophrenia. However, discovering a genetic variant predisposing to a disease is only a first step. To apply this knowledge towards prevention or cure, including tailoring treatment to the patient’s genetic profile –also known as personalized medicine – we need to know how this genetic variant affects health.

1 Aug 2013

'Dark matter' in human genome may play role in cancer biology and cell death

The St. Laurent Institute, a non-profit medical research institute focused on the systems biology of disease, today announced in a study published in the July edition of Genome Biology, that genetic matter, previously ignored by the scientific community, may play an important role in cancer.

1 Aug 2013

Genetic testing launched to identify genetic risk for kidney disease in patients with hypertension

The Icahn School of Medicine at Mount Sinai is partnering with the Institute for Family Health to launch the first-ever genetic testing program in the primary care setting to identify genetic risk for kidney disease in patients with hypertension.

1 Aug 2013

Genome News and Research

Researchers unveil comprehensive portrait of the genome of world's first immortal cell line

Brain tumor cells in arrested development contribute to cell variety that protects cancer

DNA mutation 'signature' identified in urinary tract cancers linked to birthwort herb

Cancer-linked mitosis: an interview with Professor Scott Kern, Johns Hopkins University School of Medicine

Roche releases new software for accurate sequencing of long 16S ribosomal RNA amplicons

Findings may allow lower doses of chemotherapy, limit toxic side effects

TGen receives $20,000 grant from ACF for STEM education

Study examines genetic overlap between Parkinson disease and Alzheimer disease

Study reveals nearly 40% of tumors are caused by viruses

New England Biolabs Gains Access To Advanced NGS Library Prep Method

Affymetrix introduces new OncoScan FFPE Assay Kit

Study opens door to possible treatments for variety of mitochondrial diseases

New research may influence development of anti-viral therapies to fight against Dengue

NanoString announces Early Access Program for nCounter Elements used in translational research

Wild type genetic background affects outcomes of interactions between genetic mutations

Study offers new hope for treatment of diffuse large B-cell lymphoma

Research aims to provide physicians a more targeted approach to treating ER+ breast cancer

Study proposes novel approach for understanding how genome affects biology of the human body

'Dark matter' in human genome may play role in cancer biology and cell death

Genetic testing launched to identify genetic risk for kidney disease in patients with hypertension

Genetics & Genomics - Second Edition eBook

Revolutionizing Life Science: An Interview with SCIEX on ASMS, the SCIEX 7500+ System, and AI-Driven Quantitation

From Discovery Biology to ELRIG Chair

Breathing New Life into Diagnostics: Plasmion's SICRIT Technology

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