Immune System News and Research

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Scripps Research finds molecular cause of a group of rare autoimmune disorders

A team from Scripps Research has found a molecular cause of a group of rare autoimmune disorders in which the immune system attacks the body's own healthy cells.

20 Dec 2018

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

The importance of research into the role of the immune system in the development and therapy of oncological diseases was emphasized by the Royal Swedish Academy, which recently named James Allison and Tasuku Honjo recipients of the 2018 Nobel Prize in Physiology or Medicine for launching an effective new way to attack cancer by treating the immune system rather than the tumor.

20 Dec 2018

Stress related pathway instrumental in controlling function of immune cells

The immune system is composed of a wide range of different immune cells each with dedicated functions. Natural killer T cells form a specialized immune cell that protects against a variety of diseases such as cancer, autoimmunity, metabolic disease or certain infections such as Lyme disease.

20 Dec 2018

Viral hepatitis: Liver failure caused by defects in the vascular system

In severe cases, a viral hepatitis infection can result in liver failure. A team from the Technical University of Munich has now discovered how this occurs: by immune cells attacking cells in the vascular system, which disrupts the organ's blood and nutrient supply.

19 Dec 2018

Pregnant women and extremely obese people at high risk of flu complications

Pregnant women and the extremely obese are among those at high risk for complications from the flu - including death - and should be tested and begin antiviral treatment promptly if they are sick enough to be hospitalized with flu symptoms, according to updated guidelines released by the Infectious Diseases Society of America.

19 Dec 2018

Chronic fatigue syndrome connected with an overactive immune system

A new study has shown that overactive immune systems may be the trigger that gives rise to chronic fatigue syndrome (CFS). The study results were published in the latest issue of the journal Psychoneuroendocrinology.

19 Dec 2018

EU Member States fall short on influenza vaccination coverage for vulnerable groups, says ECDC

None of the European Union (EU) Member States could demonstrate that they reach the EU target of 75% influenza vaccination coverage for vulnerable groups, according to a new report from the European Centre for Disease Prevention and Control (ECDC).

19 Dec 2018

Gut microbiome plays role in immune system regulation, study finds

Scientist have long known that bacteria in the intestines, also known as the microbiome, perform a variety of useful functions for their hosts, such as breaking down dietary fiber in the digestive process and making vitamins K and B7.

19 Dec 2018

FSU researchers discover how breast cancer evades immune system detection

Recent breakthroughs in immunotherapy are making a huge difference in treating some forms of cancer, especially metastatic cancer. But breast cancer has proven a tricky foe for this new therapy, and an interdisciplinary team of FSU researchers is now a little bit closer to figuring out why.

18 Dec 2018

Combination of a vaccine and checkpoint drugs reduces pancreatic tumors in mice

Researchers at the Johns Hopkins Kimmel Cancer Center discovered a combination of a cancer vaccine with two checkpoint drugs reduced pancreatic cancer tumors in mice, demonstrating a possible pathway for treatment of people with pancreatic cancers whose response to standard immunotherapy is poor.

18 Dec 2018

Metal-based chemotherapy enhances the effect of cancer immunotherapy

Due to their powerful tumor-killing effect, metal-based chemotherapies are frequently used in cancer treatment. However, it was hitherto assumed that they damaged the immune system, because of their cytotoxic (cell-damaging) effect even against dividing healthy cells.

18 Dec 2018

Researchers identify potential target for new breast cancer treatments

Researchers from the School of Basic & Medical Biosciences have identified a potential target that could lead to new treatments for triple negative breast cancer.

18 Dec 2018

Russian scientists identify molecular 'switch' that could be target for treatment of allergic asthma

A team of Russian scientists identified the role of the interleukin-6 molecule in the development of allergic asthma. Now it can be a new target for the treatment of this disease. The results are published in Frontiers in Immunology.

17 Dec 2018

National Biofilms Innovation Centre award grant to Neem Biotech for novel anti-biofilm drug development

Neem Biotech, Welsh Wound Innovation Centre and Sheffield Collaboratorium for Antimicrobial Resistance and Biofilms Awarded NBIC Grant to Advance Development of Neem’s First-in-Class Treatments for Wound Infections.

From Neem Biotech 17 Dec 2018

Immune cells explode themselves to inform about the danger of invading bacteria

Our immune systems are working overtime this time of year. Knowing that a bunch of dedicated immune cells are willing to explode themselves to inform other cells about the danger may offer a bit of consolation.

17 Dec 2018

Researchers reveal how key transcription factor keeps the immune system in check

Our immune systems defend our bodies against dangerous invaders and help clean up when damage is done. But if our bold protectors are left unsupervised, they sometimes do their jobs too well and end up harming healthy tissues.

17 Dec 2018

Experimental HIV vaccine strategy works in non-human primates, research shows

For more than 20 years, scientists at Scripps Research have chipped away at the challenges of designing an HIV vaccine. Now new research, published in Immunity, shows that their experimental vaccine strategy works in non-human primates.

14 Dec 2018

Recurrence of urinary tract infection may depend on bacterial strain, study shows

Genetically diverse bacterial strains that cause urinary tract infections differ in their ability to trigger protective immune responses in mice, potentially explaining why these infections frequently recur in many patients, according to a study published December 13 in the open-access journal PLOS Pathogens by Thomas Hannan and Scott Hultgren of Washington University School of Medicine, and colleagues.

14 Dec 2018

Weakened metabolism of immune T cells may account for serious complications in elderly

The elderly suffer more serious complications from infections and benefit less from vaccination than the general population.

14 Dec 2018

New findings could help develop new immunotherapies against cancer

NK cells, or natural killer cells, play an important role in the body's defences against cancer and various infections.

14 Dec 2018

Immune System News and Research

Scripps Research finds molecular cause of a group of rare autoimmune disorders

Scientists investigate potential of nanomaterials to activate the body's antitumor immune response

Stress related pathway instrumental in controlling function of immune cells

Viral hepatitis: Liver failure caused by defects in the vascular system

Pregnant women and extremely obese people at high risk of flu complications

Chronic fatigue syndrome connected with an overactive immune system

EU Member States fall short on influenza vaccination coverage for vulnerable groups, says ECDC

Gut microbiome plays role in immune system regulation, study finds

FSU researchers discover how breast cancer evades immune system detection

Combination of a vaccine and checkpoint drugs reduces pancreatic tumors in mice

Metal-based chemotherapy enhances the effect of cancer immunotherapy

Researchers identify potential target for new breast cancer treatments

Russian scientists identify molecular 'switch' that could be target for treatment of allergic asthma

National Biofilms Innovation Centre award grant to Neem Biotech for novel anti-biofilm drug development

Immune cells explode themselves to inform about the danger of invading bacteria

Researchers reveal how key transcription factor keeps the immune system in check

Experimental HIV vaccine strategy works in non-human primates, research shows

Recurrence of urinary tract infection may depend on bacterial strain, study shows

Weakened metabolism of immune T cells may account for serious complications in elderly

New findings could help develop new immunotherapies against cancer

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