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Study shows no added benefit of pertuzumab combination in treatment of early breast cancer

For the third time since 2013, the German Institute for Quality and Efficiency in Health Care (IQWiG) examined in an early benefit assessment the added benefit of the drug pertuzumab in the treatment of HER2-positive breast cancer.

12 Oct 2018

Discovery of gene mutation could offer benefit for people suffering from diabetes, heart disease, obesity

Researchers say they have discovered a gene mutation that slows the metabolism of sugar in the gut, giving people who have the mutation a distinct advantage over those who do not.

10 Oct 2018

University of Houston biologist explores therapeutic targets to prevent atherosclerosis

University of Houston biologist Michihisa Umetani, having discovered that a certain protein partnership acts to rapidly signal molecules inside blood vessels that danger is upon them, has been awarded $382,500 by the National Institutes of Health.

10 Oct 2018

Bridge-like structure within estrogen receptor could serve as new drug target for breast cancer

Many breast cancer drugs block estrogen receptors inside cancer cells. Blocking the receptors early in disease progression staves off metastasis.

10 Oct 2018

Binge drinking history makes male and female mice react differently to stress, study shows

Researchers with the Veterans Affairs Portland Health Care System and Oregon Health & Sciences University found that a history of binge drinking made male and female mice react differently to traumatic stress.

10 Oct 2018

Scientists discover pheromone-sensing gene that predates land-dwelling vertebrates

Scientists at Tokyo Institute of Technology have discovered a gene that appears to play a vital role in pheromone sensing. The gene is conserved across fish and mammals and over 400 million years of vertebrate evolution, indicating that the pheromone sensing system is much more ancient than previously believed.

10 Oct 2018

Antibody Screening Tools; Improving Workflows

Antibody screening tools have exponentially increased the rate that candidates can be screened, multiplexing will increase processing to thousands per hour.¬

From Sartorius 9 Oct 2018

'Supercharged' immune cells could help fight cancer

A type of 'supercharged' immune cell could be mass-produced to help fight cancer.

9 Oct 2018

Arcus Biosciences announces presentation of final results from Phase 1 study of AB928 at ESMO 2018

Arcus Biosciences, Inc., a clinical-stage biopharmaceutical company focused on creating innovative cancer immunotherapies, today announced that it will present final results from the Phase 1 study of AB928, its dual adenosine receptor antagonist, in healthy volunteers during a poster display session at the European Society of Medical Oncology 2018 Congress, being held October 19-23, 2018, in Munich, Germany.

8 Oct 2018

Neoadjuvant clinical trial of immune checkpoint blockade for melanoma patients yields high response rate

Combination checkpoint blockade before surgery (neoadjuvant therapy) produced a high response rate among patients with high-risk stage 3 melanoma, with nearly half having no sign of disease at surgery, but a high incidence of side effects caused the trial to be closed early.

8 Oct 2018

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Verastem, Inc., focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced that the National Comprehensive Cancer Network added COPIKTRA (duvelisib) capsules to the Clinical Practice Guidelines in Oncology (NCCN Guidelines) for follicular lymphoma.

8 Oct 2018

Joint research team discovers potential new treatment for severe malaria

Scientists from Massachusetts Institute of Technology, Singapore-MIT Alliance for Research and Technology and Nanyang Technological University, Singapore have discovered a potential treatment that could be effective against severe malaria and even drug-resistant malaria.

8 Oct 2018

FDA and EMA accept Novartis' regulatory application for siponimod to treat SPMS in adults

Novartis today announced that both the US Food and Drug Administration and European Medicines Agency have accepted the company's New Drug Application and Marketing Authorization Application respectively, for investigational oral, once-daily siponimod (BAF312) for the treatment of secondary progressive multiple sclerosis in adults.

8 Oct 2018

New blood test may detect early-stage lung cancer when surgical intervention is not possible

Non-small-cell lung carcinoma is often fatal because most cases are not diagnosed until they are so advanced that surgical intervention is no longer possible. To improve outcomes researchers are developing a blood test to detect lung cancer earlier in the disease.

8 Oct 2018

Vaxart to present new data from Phase 2 Challenge Study of H1 influenza oral tablet vaccine

Vaxart, Inc., a clinical-stage biotechnology company developing oral recombinant vaccines that are administered by tablet rather than by injection, announced it will present new data from the Phase 2 Challenge Study of its H1 influenza oral tablet vaccine at IDWeek 2018 in San Francisco on Saturday, October 6, 2018.

4 Oct 2018

Triangular-shaped neurons found in the brain help us recognize and categorize food

Brain regions best known for recognizing the potential horror of a hurricane also help us recognize, appreciate and categorize our food, scientists report.

4 Oct 2018

Appetite-suppressant drug reduces diabetes risk and increases remission rates of blood sugar

New research presented at this year's annual meeting of the European Association for the Study of Diabetes in Berlin, Germany, and published in The Lancet, shows that the appetite-suppressant drug lorcaserin decreases risk of developing diabetes and increases the rates of remission of high blood sugar.

4 Oct 2018

New PET imaging radiotracer could help understand the aging brain

A new PET imaging radiotracer could help researchers understand neurodegenerative disease and the aging brain. The study is featured in the October issue of The Journal of Nuclear Medicine.

4 Oct 2018

Stevens researchers develop new class of molecules for breast cancer treatment

Researchers at Stevens Institute of Technology and colleagues have designed and developed a new class of molecules that use a never-before-known mechanism that may halt or destroy breast cancer tumors, particularly for patients with drug-resistant or dangerously metastatic stages of the disease.

4 Oct 2018

Study investigates effects of glucose-lowering drug in preventing damage to the kidneys

New research presented at the annual meeting of the European Association for the Study of Diabetes and published simultaneously in The Lancet Diabetes & Endocrinology shows how the glucose-lowering drug lixisenatide can slow or prevent damage to the kidneys in macro-albuminuric patients with type 2 diabetes mellitus and cardiovascular disease.

3 Oct 2018

Receptor News and Research

Study shows no added benefit of pertuzumab combination in treatment of early breast cancer

Discovery of gene mutation could offer benefit for people suffering from diabetes, heart disease, obesity

University of Houston biologist explores therapeutic targets to prevent atherosclerosis

Bridge-like structure within estrogen receptor could serve as new drug target for breast cancer

Binge drinking history makes male and female mice react differently to stress, study shows

Scientists discover pheromone-sensing gene that predates land-dwelling vertebrates

Antibody Screening Tools; Improving Workflows

'Supercharged' immune cells could help fight cancer

Arcus Biosciences announces presentation of final results from Phase 1 study of AB928 at ESMO 2018

Neoadjuvant clinical trial of immune checkpoint blockade for melanoma patients yields high response rate

NCCN adds COPIKTRA capsules to NCCN Guidelines for follicular lymphoma

Joint research team discovers potential new treatment for severe malaria

FDA and EMA accept Novartis' regulatory application for siponimod to treat SPMS in adults

New blood test may detect early-stage lung cancer when surgical intervention is not possible

Vaxart to present new data from Phase 2 Challenge Study of H1 influenza oral tablet vaccine

Triangular-shaped neurons found in the brain help us recognize and categorize food

Appetite-suppressant drug reduces diabetes risk and increases remission rates of blood sugar

New PET imaging radiotracer could help understand the aging brain

Stevens researchers develop new class of molecules for breast cancer treatment

Study investigates effects of glucose-lowering drug in preventing damage to the kidneys

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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