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Unique method opens door to development of simple diagnostic tests for myriad diseases

Researchers at the University of Pittsburgh have developed a unique method for detecting antibodies in the blood of patients in a proof-of-principle study that opens the door to development of simple diagnostic tests for diseases for which no microbial cause is known, including auto-immune diseases, cancers and other conditions.

10 Jun 2016

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

The results of a study presented today at the European League Against Rheumatism Annual Congress showed that tiny particles made of a biodegradable polymer (BNPs -- biodegradable polymer nanoparticles) have the potential to enable early detection and efficient long-term treatment of rheumatoid arthritis (RA), with minimal side effects.

10 Jun 2016

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

Much of basic cancer research is based on studies with cultured cancer cells. However, the usefulness of these studies greatly depends on how accurately these cancer cells grown in a dish represent human tumors.

9 Jun 2016

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

Professor Claudio Luchinat, University of Florence and co-founder of the Magnetic Resonance Center (CERM), speaks to News-Medical about his research in NMR-based metabolomics.

From Bruker BioSpin Division 9 Jun 2016

New blood test helps detect MCI stage of Alzheimer's disease

A research team, led by Dr. Robert Nagele from Rowan University School of Osteopathic Medicine and Durin Technologies, Inc., has announced the development of a blood test that leverages the body's immune response system to detect an early stage of Alzheimer's disease - referred to as the mild cognitive impairment (MCI) stage - with unparalleled accuracy.

8 Jun 2016

New study sheds light on impact of unknown genetic mutations in cystic fibrosis patients

When it comes to cystic fibrosis (CF), more than 2,000 different genetic mutations have been reported. However, only 200 of them have been categorized - leaving a genetic soup of 1,800 others for scientists and genetic counselors to figure out.

8 Jun 2016

Panel of microRNAs can predict patients at risk for developing HBV-driven liver cancer

Hepatocellular carcinoma, the most common type of liver cancer, is increasing in incidence in the United States, and infection with the Hepatitis B virus (HBV) causes about 50 percent of cases.

7 Jun 2016

New technique helps identify link between fatty acids and breast cancer in postmenopausal women

The presence of high saturated fatty acids in breast tissue may be a useful indicator of cancer in postmenopausal women, according to a new study by researchers at NYU Langone Medical Center, published online June 7 in Radiology, a journal of the Radiological Society of North America.

7 Jun 2016

Rare DNA alteration may increase rsk of multiple sclerosis

Scientists at the University of British Columbia and Vancouver Coastal Health have proven that multiple sclerosis (MS) can be caused by a single genetic mutation - a rare alteration in DNA that makes it very likely a person will develop the more devastating form of the neurological disease.

6 Jun 2016

CMR could offer complete imaging solution before pulmonary vein isolation

Cardiac magnetic resonance can potentially be used to detect thrombi at the same time as being used for pulmonary venous anatomy mapping, say researchers

4 Jun 2016

Rapid NSTEMI exclusion becoming reality

Two studies show that modern high-sensitivity troponin I assays can help physicians to rapidly identify patients with a very low likelihood of having non-ST-segment elevation myocardial infarction.

4 Jun 2016

Understanding mechanisms of aortic pathology to improve care

Aortic disease, including aortic aneurysm and aortic dissection, is an important cause of cardiovascular morbidity and death. There have been exciting developments in caring for patients with aortic aneurysm and dissection, including great advances in diagnosis and endovascular therapies.

2 Jun 2016

Advanced imaging kit Netspot gets FDA approval to detect rare neuroendocrine tumors

The U.S. Food and Drug Administration today approved Netspot, the first kit for the preparation of gallium Ga 68 dotatate injection, a radioactive diagnostic agent for positron emission tomography (PET) imaging.

2 Jun 2016

Food intolerance expert Dr Gill Hart warns parents over proposed Nestle milk allergy testing

This week Nestle has announced it will develop and market a milk allergy skin patch test for infants, in a bid to boost sales of formula to babies with allergies.

2 Jun 2016

VirtaMed introduces new hip arthroscopy simulator at EFORT Congress

Safe access training for portal placement all wrapped in a combination of an extremely realistic anatomic model and a high-fidelity virtual reality environment.

From VirtaMed 2 Jun 2016

GET.ON online training course can effectively reduce depression risk

Inspired by promising tests of web-based health intervention measures, the researchers aimed to find out whether the risk of developing depression could be reduced by a six-week online training course called GET.ON. GET.ON is based on established therapy methods involving systematic problem solving and behavioural activation.

2 Jun 2016

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

The U.S. Food and Drug Administration today approved the cobas EGFR Mutation Test v2, a blood-based companion diagnostic for the cancer drug Tarceva (erlotinib). This is the first FDA-approved, blood-based genetic test that can detect epidermal growth factor receptor (EGFR) gene mutations in non-small cell lung cancer patients.

2 Jun 2016

Using proteomic mass spectrometry imaging to detect malignant melanoma: an interview with Stephen Turner

Today, using anatomic pathology, the differences in appearance of a normal or a malignant lesion can be difficult to tell when just using light microscopy.

2 Jun 2016

New roadmap can help guide researchers to speed up biomarker-based research on Alzheimer's disease

Biomarkers could revolutionise the early detection of and therapy for Alzheimer's disease. However, experts attending the Congress of the European Academy of Neurology in Copenhagen criticized that the big breakthroughs are slow in coming because of a lack of priorities in research.

1 Jun 2016

Brain scan combined with long-term memory test could help early Alzheimer's diagnosis

People with Alzheimer's disease could benefit from earlier diagnosis if a long-term memory test combined with a brain scan were carried out, a study suggests.

1 Jun 2016

Diagnostic News and Research

Unique method opens door to development of simple diagnostic tests for myriad diseases

BNPs have potential to enable early diagnosis, long-term treatment of RA with minimal side effects

Whole-exome sequencing can help characterize genetic alterations for commonly used bladder cancer cell lines

NMR-based metabolomics: an interview with Prof. Claudio Luchinat

New blood test helps detect MCI stage of Alzheimer's disease

New study sheds light on impact of unknown genetic mutations in cystic fibrosis patients

Panel of microRNAs can predict patients at risk for developing HBV-driven liver cancer

New technique helps identify link between fatty acids and breast cancer in postmenopausal women

Rare DNA alteration may increase rsk of multiple sclerosis

CMR could offer complete imaging solution before pulmonary vein isolation

Rapid NSTEMI exclusion becoming reality

Understanding mechanisms of aortic pathology to improve care

Advanced imaging kit Netspot gets FDA approval to detect rare neuroendocrine tumors

Food intolerance expert Dr Gill Hart warns parents over proposed Nestle milk allergy testing

VirtaMed introduces new hip arthroscopy simulator at EFORT Congress

GET.ON online training course can effectively reduce depression risk

FDA approves blood-based cobas EGFR Mutation Test v2 for NSCLC patients

Using proteomic mass spectrometry imaging to detect malignant melanoma: an interview with Stephen Turner

New roadmap can help guide researchers to speed up biomarker-based research on Alzheimer's disease

Brain scan combined with long-term memory test could help early Alzheimer's diagnosis

Improving healthcare sustainability through carbon data

A New Approach to Preventing Bladder Cancer Recurrence

Bringing real-time analytics to downstream bioprocess monitoring

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