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Concert to advance CTP-499, C-21191 into Phase 2 trials for diabetic nephropathy and spasticity

Concert Pharmaceuticals, Inc. announced today the advancement of two programs from its DCE Platform. CTP-499 is progressing into Phase 2 clinical trials for diabetic nephropathy and C-21191 has been selected as a lead candidate for spasticity.

20 Jun 2011

Study: Dyslexia gene controls cilia in brain neurons

Scientists at Karolinska Institutet in Sweden have discovered that a gene linked to dyslexia has a surprising biological function: it controls cilia, the antenna-like projections that cells use to communicate.

20 Jun 2011

Targeting activity of PKD1 may be beneficial for treatment of polycystic kidney, liver disease

A single gene is central in the development of several forms of polycystic kidney and liver disease, Yale School of Medicine researchers report in the June 19 issue of Nature Genetics.

20 Jun 2011

MA launches national campaign to raise awareness on meningitis

This Father's Day is a special day for Angels Dads on Meningitis (ADOM). Angel dads from across the country came together in Denver, Colorado to launch a national campaign on meningitis awareness.

20 Jun 2011

FDA approves NULOJIX

Bristol-Myers Squibb Company announced that the U.S. Food and Drug Administration (FDA) approved NULOJIX, the first selective T-cell costimulation blocker indicated for the prophylaxis of organ rejection in adult patients receiving a kidney transplant, in combination with basiliximab induction, mycophenolate mofetil (MMF), and corticosteroids.

18 Jun 2011

High rates of type 1 diabetes in Australian children

According to a new report the rate of Type 1 diabetes in Australian children will leap by 10 per cent in the five years to 2013, cementing Australia's position in the top 10 OECD nations for the condition's prevalence. Currently the prevalence of diabetes in Australia ranks seventh-highest among the 30 OECD nations.

17 Jun 2011

Adolescent obese males at risk of cancer later in life: Study

According to a new study, men who are obese as teenagers are at a greater risk of cancer. Researchers claim that the risk remains even among those who lose weight later in life.

17 Jun 2011

Loyola employee donates kidney to complete stranger, saves her own life

When Dorothy Jambrosek, 47, decided to donate a kidney to a stranger, she didn't realize that her goodwill would save her own life. After undergoing a series of tests required to give a kidney, doctors discovered that Jambrosek had precancerous lesions in her breast that could become cancerous.

17 Jun 2011

Phosphate regulating hormone associated with increased risk of kidney failure and death among CKD patients

A high level of a hormone that regulates phosphate is associated with an increased risk of kidney failure and death among chronic kidney disease (CKD) patients, according to a recent study led by researchers at the University of Miami and funded by the National Institute of Diabetes and Digestive Diseases and Kidney Diseases (NIDDK) at the National Institutes of Health.

16 Jun 2011

Bristol-Myers Squibb receives FDA approval for Nulojix to prevent organ rejection after kidney transplant

The U.S. Food and Drug Administration today approved Nulojix to prevent acute rejection in adult patients who have had a kidney transplant. The drug is approved for use with other immunosuppressants -- specifically basiliximab, mycophenolate mofetil, and corticosteroids.

16 Jun 2011

Magnesium essential for absorption and metabolism of vitamin D and calcium

Magnesium deficiency is an important factor in the results obtained from vitamin D. According to Dr. Carolyn Dean, MD, ND, magnesium expert and Medical Director of the nonprofit Nutritional Magnesium Association, the effectiveness and benefits of vitamin D are greatly undermined in the absence of adequate levels of magnesium in the body.

15 Jun 2011

Overactive mTOR can result in serious disruption of kidney filter in diabetes patients

Diabetes mellitus is one of the most common secondary diseases in modern society. And because it is on the rise, it is also one of the greatest challenges facing medicine today. Diabetes patients do not die as a direct result of the increase in blood sugar, but from the long-term complications of their disease, in which the increase in blood sugar causes damage to blood vessels and organs.

15 Jun 2011

Childhood cancer survivors at increased risk of new cancers in middle age

CANCER RESEARCH UK scientists have found that survivors of childhood cancers are four times more likely than the general population to develop a new cancer. The results are published online today in JAMA.

15 Jun 2011

High FGF-23 hormone levels linked to increased risk of end-stage renal disease and death

Patients in the early stages of chronic kidney disease who had elevated levels of the endocrine hormone fibroblast growth factor 23 (that regulates phosphorus metabolism) had an associated increased risk of end-stage renal disease and death, according to a study in the June 15 issue of JAMA.

15 Jun 2011

CorMedix completes enrollment in CRMD001 Phase II trial for treatment of acute kidney injury

CorMedix Inc., a pharmaceutical company focused on developing and commercializing therapeutic products for the prevention and treatment of cardiorenal disease, announced it successfully completed patient enrollment in its phase II Contrast-Induced Acute Kidney Injury study with its oral drug candidate CRMD001.

14 Jun 2011

C-Path, IMI sign MoU to accelerate development of safer, more effective medicines for patients

Critical Path Institute (C-Path) and the Innovative Medicines Initiative (IMI) announced today that they have signed a Memorandum of Understanding (MoU) to further the missions of both organizations.

14 Jun 2011

Poor maternal nutrition predisposes offspring to type 2 diabetes

A new study published by the American Physiological Society offers the strongest evidence yet that vulnerability to type 2 diabetes can begin in the womb, giving new insight into the mechanisms that underlie a potentially devastating disease at the center of a worldwide epidemic.

14 Jun 2011

Kidney News and Research

Concert to advance CTP-499, C-21191 into Phase 2 trials for diabetic nephropathy and spasticity

Study: Dyslexia gene controls cilia in brain neurons

Targeting activity of PKD1 may be beneficial for treatment of polycystic kidney, liver disease

MA launches national campaign to raise awareness on meningitis

FDA approves NULOJIX

High rates of type 1 diabetes in Australian children

Adolescent obese males at risk of cancer later in life: Study

Loyola employee donates kidney to complete stranger, saves her own life

Phosphate regulating hormone associated with increased risk of kidney failure and death among CKD patients

Bristol-Myers Squibb receives FDA approval for Nulojix to prevent organ rejection after kidney transplant

Magnesium essential for absorption and metabolism of vitamin D and calcium

Overactive mTOR can result in serious disruption of kidney filter in diabetes patients

Childhood cancer survivors at increased risk of new cancers in middle age

High FGF-23 hormone levels linked to increased risk of end-stage renal disease and death

CorMedix completes enrollment in CRMD001 Phase II trial for treatment of acute kidney injury

C-Path, IMI sign MoU to accelerate development of safer, more effective medicines for patients

Poor maternal nutrition predisposes offspring to type 2 diabetes

Calcium-sensing receptor plays key role in lethal lung cancer complication

Mother to donate her womb to daughter

Nose spray vaccine for type 1 diabetes could be a reality soon

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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