B Cell News and Research

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Decreased viral infection severity in females may be due to extra copy of X chromosome-linked gene

It has long been known that viral infections can be more severe in males than females, but the question as to why has remained a mystery – until possibly now.

17 Mar 2023

Researchers find new way to remove waste after brain hemorrhage

University of Helsinki and Taiwanese researchers have found a new way to remove waste from the brain after hemorrhage.

17 Mar 2023

Scientists develop a marker for therapy response in acute myeloid leukemia

With the combination of the drugs Venetoclax and 5-Azacitidine, a new, effective and more tolerable alternative to chemotherapy for the treatment of AML has been available for several years. But for some patients, the drug combination does not work.

17 Mar 2023

Designer DNA drug could be used to delay paralysis in ALS

In virtually all persons with amyotrophic lateral sclerosis (ALS) and in up to half of all cases of Alzheimer's disease (AD) and frontotemporal dementia, a protein called TDP-43 is lost from its normal location in the nucleus of the cell.

17 Mar 2023

Study reveals the underlying mechanism by which TKI cancer drugs cause inflammation

Tyrosine kinase inhibitors are a type of targeted cancer medicine that can attack specific types of cancer cells and prevent them from multiplying.

17 Mar 2023

Stanford researchers study causes of and treatments for long COVID

Time heals many wounds. But not all of them.

17 Mar 2023

How the structural and functional effects of mutations on androgen receptor lead to prostate cancer

The androgen receptor is a key transcriptional factor for the proper sex development —specially in males— and the physiological balance of all the tissues that express this receptor.

17 Mar 2023

Loss of a beta cell subset might contribute to type 2 diabetes

Multiple types of beta cells produce insulin in the pancreas, helping to balance blood sugar levels. Losing a particularly productive type of beta cell may contribute to the development of diabetes, according to a new study by Weill Cornell Medicine investigators.

17 Mar 2023

When mass spectrometry redefines molecular biology and biochemistry – the future of spatial omics

In this interview, Bruker speaks with Ramon Sun on the topic of SpatialOMx - a field that is currently experiencing great changes. Dive in to discover how Bruker will rise to the challenge.

From Bruker Daltonics 17 Mar 2023

Does vitamin D play an anti-viral role against SARS-CoV-2?

Researchers screened various compounds for anti-viral properties against SARS-CoV-2.

17 Mar 2023

Anti-Omicron antibodies are induced by hypermutation with ancestral BNT162b2 COVID vaccine

Scientists from the Republic of Korea have analyzed B-cell receptor repertoires induced by an mRNA-based coronavirus disease 2019 (COVID-19) vaccine and found that somatic hypermutations in B-cell receptor heavy chain are responsible for broadening its specificity for unexposed antigens.

16 Mar 2023

Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

In a recent study posted to the bioRxiv* preprint server, researchers in the United States described a blocking enzyme-linked immunosorbent assay (ELISA) to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) exposure in animals.

16 Mar 2023

Study implicates gut microbiome and immune response in hospital-acquired infections

In a recent study published in the journal Nature Medicine, researchers at the University of Calgary analyzed the dynamics of fecal microbiota and conducted single-cell profiling of inflammatory responses and systemic immunity to determine associations between gut microbiome dysbiosis and an increased risk of nosocomial infections.

16 Mar 2023

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

Researchers examine whether the involvement of the ipsilateral or contralateral lymph nodes affected the immune response during sequential vaccination.

16 Mar 2023

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Testing of ambient air can be used to monitor the community circulation of respiratory pathogens.

16 Mar 2023

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

In a Phase II trial led by researchers from The University of Texas MD Anderson Cancer Center, adding ipilimumab to a neoadjuvant, or pre-surgical, combination of nivolumab plus platinum-based chemotherapy, resulted in a major pathologic response (MPR) in half of all treated patients with early-stage, resectable non-small cell lung cancer (NSCLC).

16 Mar 2023

B Cell News and Research

Decreased viral infection severity in females may be due to extra copy of X chromosome-linked gene

Researchers find new way to remove waste after brain hemorrhage

Scientists develop a marker for therapy response in acute myeloid leukemia

Designer DNA drug could be used to delay paralysis in ALS

Study reveals the underlying mechanism by which TKI cancer drugs cause inflammation

Stanford researchers study causes of and treatments for long COVID

How the structural and functional effects of mutations on androgen receptor lead to prostate cancer

Loss of a beta cell subset might contribute to type 2 diabetes

When mass spectrometry redefines molecular biology and biochemistry – the future of spatial omics

Does vitamin D play an anti-viral role against SARS-CoV-2?

Anti-Omicron antibodies are induced by hypermutation with ancestral BNT162b2 COVID vaccine

Monoclonal antibody-based blocking ELISA for SARS-CoV-2 detection in animals

Study implicates gut microbiome and immune response in hospital-acquired infections

Ipsilateral vaccination improves response to second dose of COVID-19 vaccine

Research highlights the importance of ventilation and air filtration to reduce pathogen transmission

Trial shows encouraging results for neoadjuvant dual immunotherapy and chemotherapy in patients with resectable NSCLC

Detecting tissue-resident memory T cells in solid tumors

Creating more effective and safe treatments for COVID-19

Study highlights a persistent life expectancy gap among patients living with sickle cell disease

Scientists develop genetically defined mouse models for multiple myeloma subtypes

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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