Clinical Trial News and Research

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WRAIR begins Phase 1 clinical trial to evaluate MERS vaccine candidate

The Walter Reed Army Institute of Research began vaccinations today in a Phase 1 clinical trial to evaluate the safety and immune response of a vaccine candidate to prevent Middle East Respiratory Syndrome (MERS).

17 Feb 2016

Asterias Biotherapeutics simplifies capital structure through previously announced Asset Swap with BioTime

Asterias Biotherapeutics, Inc., a clinical-stage regenerative medicine company with a focus on pluripotent stem cell technology, today simplified its capital structure through the previously announced Asset Swap with BioTime, Inc.

17 Feb 2016

CTI BioPharma announces Q4 and FY 2015 earnings

CTI BioPharma Corp. today reported financial results for the fourth quarter and full year ended December 31, 2015.

17 Feb 2016

Apogenix awarded €3 million grant to develop immuno-oncology candidate APG101 as personalized therapy

Apogenix, a biopharmaceutical company developing next generation immuno-oncology therapeutics, announced today that it has received funding approval in the amount of €3 million from the German Federal Ministry of Education and Research for the so-called CancerMark project.

16 Feb 2016

Celator provides update on Phase 3 clinical trial of VYXEOS in patients with untreated high-risk AML

Celator Pharmaceuticals, Inc. today announced that the Phase 3 clinical trial of VYXEOS (cytarabine:daunorubicin) Liposome for Injection (also known as CPX-351) in patients with untreated high-risk (secondary) acute myeloid leukemia (AML) has reached its pre-specified number of events required for the analysis of overall survival.

16 Feb 2016

First two patients treated in multi-center clinical trial for perivascular renal denervation

Ablative Solutions, Inc. (ASI), a privately held company headquartered in Kalamazoo, MI, with offices in Palo Alto, CA, announced today that Professors Wojtek Wojakowski and Mariusz Hochul have treated the first two patients in the European Peregrine Post-Market Study.

16 Feb 2016

Vascular surgery safer than stenting for older patients with carotid stenosis

Vascular surgery appears to be safer than stenting for patients over 70 years of age with carotid stenosis, or a blockage of the carotid arteries in the neck, according to new findings published today in the Lancet.

16 Feb 2016

Amgen announces availability of Kyprolis (carfilzomib) in the UK for treatment of relapsed multiple myeloma

Amgen today announced that Kyprolis in combination with lenalidomide and dexamethasone is now available in the UK for the treatment of adult patients with multiple myeloma who have received at least one prior therapy.

16 Feb 2016

First patients dosed in Neurotrope's Bryostatin-1 Phase 2b trial for treatment of advanced Alzheimer’s disease

Neurotrope, Inc. today announced that the first patients have been dosed in the Company’s Phase 2b clinical trial of its lead candidate, Bryostatin-1, for the treatment of advanced Alzheimer’s disease.

16 Feb 2016

New UAB research shows association between verapamil use and lower glucose levels in diabetics

A new University of Alabama at Birmingham research paper published in the journal Diabetes Research and Clinical Practice shows for the first time that there is an association of verapamil use and lower fasting glucose levels in humans with diabetes.

15 Feb 2016

Anti-cancer drug delays onset of Alzheimer's disease

Researchers have identified a drug that targets the first step in the toxic chain reaction leading to the death of brain cells, suggesting that treatments could be developed to protect against Alzheimer's disease, in a similar way to how statins are able to reduce the risk of developing heart disease.

15 Feb 2016

Researchers find new way to increase patients’ recruitment, retention in clinical trials

By seeking the advice of patients, families and other stakeholders in designing a clinical trial investigating pediatric appendicitis, researchers at Nationwide Children's Hospital found a way to significantly increase the number of people recruited and retained in the trial.

12 Feb 2016

Ultrasound-activated microbubbles help preserve healthy heart tissue

Researchers funded by the National Institute of Biomedical Imaging and Bioengineering used ultrasound-activated microbubbles to improve preservation of heart muscle and function in a pig heart attack model.

12 Feb 2016

Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

A clinical trial of an experimental drug for treatment-resistant major depression finds that modulation of the endogenous opioid system may improve the effectiveness of drugs that target the action of serotonin and related monoamine neurotransmitters.

12 Feb 2016

Liverpool researchers reach major milestone towards creating diagnostic test for prostate cancer

A research team from the University of Liverpool has reached an important milestone towards creating a urine diagnostic test for prostate cancer that could mean that invasive diagnostic procedures that men currently undergo eventually become a thing of the past.

12 Feb 2016

Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

Neurocrine Biosciences, Inc. today announced its financial results for the quarter and year ended December 31, 2015.

12 Feb 2016

ASTRO's new research journal 'Advances in Radiation Oncology' closes first issue

Advances in Radiation Oncology, ASTRO's new original research journal, has closed its first issue with research including a phase II clinical trial in prostate cancer, a prospective trial in quality of life for breast cancer patients receiving radiotherapy and several clinical and medical physics reports on the use of stereotactic body radiotherapy.

12 Feb 2016

Novel test could help get best treatment for advanced bowel cancer patients

A NEW test could help patients with advanced bowel cancer get the best treatment for their disease, according to a Cancer Research UK clinical trial published today (Thursday) in JAMA Oncology.

11 Feb 2016

Oral therapeutic drug shows promise against recurrent C. difficile infection

Results from a Phase 1b/2 trial suggest that an investigational microbiome-based, oral therapeutic drug is effective for the treatment of recurrent C. difficile infection. In a paper published online in the Journal of Infectious Diseases, a multi-institutional research team reports that treatment with the preparation, containing the spores of approximately 50 species of beneficial bacteria, successfully prevented recurrence of C. difficile infection (CDI) in patients with a history of multiple recurrent disease.

10 Feb 2016

UC San Diego School of Medicine launches new NAFLD Research Center

Roughly one-quarter of all Americans - an estimated 100 million adults and children - have nonalcoholic fatty liver disease (NAFLD), a chronic condition that can lead to cirrhosis, liver cancer and liver failure.

9 Feb 2016

Clinical Trial News and Research

WRAIR begins Phase 1 clinical trial to evaluate MERS vaccine candidate

Asterias Biotherapeutics simplifies capital structure through previously announced Asset Swap with BioTime

CTI BioPharma announces Q4 and FY 2015 earnings

Apogenix awarded €3 million grant to develop immuno-oncology candidate APG101 as personalized therapy

Celator provides update on Phase 3 clinical trial of VYXEOS in patients with untreated high-risk AML

First two patients treated in multi-center clinical trial for perivascular renal denervation

Vascular surgery safer than stenting for older patients with carotid stenosis

Amgen announces availability of Kyprolis (carfilzomib) in the UK for treatment of relapsed multiple myeloma

First patients dosed in Neurotrope's Bryostatin-1 Phase 2b trial for treatment of advanced Alzheimer’s disease

New UAB research shows association between verapamil use and lower glucose levels in diabetics

Anti-cancer drug delays onset of Alzheimer's disease

Researchers find new way to increase patients’ recruitment, retention in clinical trials

Ultrasound-activated microbubbles help preserve healthy heart tissue

Modulation of opioid system may improve effectiveness of drugs for treatment-resistant depression

Liverpool researchers reach major milestone towards creating diagnostic test for prostate cancer

Neurocrine Biosciences reports net loss of $29.3 million for fourth quarter 2015

ASTRO's new research journal 'Advances in Radiation Oncology' closes first issue

Novel test could help get best treatment for advanced bowel cancer patients

Oral therapeutic drug shows promise against recurrent C. difficile infection

UC San Diego School of Medicine launches new NAFLD Research Center

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