Drugs News and Research

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Other molecules may have greater potential as cancer therapies than gold complex auranofin

The gold complex auranofin has traditionally been used for treating rheumatism but is also being evaluated as a treatment for certain forms of cancer.

22 Nov 2021

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Researchers synthesize carbon dots using different precursors and studied their antimicrobial effects in gram-negative bacteria.

22 Nov 2021

Examining the effects of malaria parasites on global health

News-Medical speaks to Professor Kevin Baird about his lifelong research into malaria and how another malaria parasite, P. Vivax, is taking a toll on global health.

22 Nov 2021

Success of covid antiviral pills hinges on access to speedy and accurate tests

Within a few weeks, perhaps before many Americans finish decorating for the holidays, the U.S. could have access to a new antiviral pill from Merck expected to alter the deadly trajectory of the covid-19 pandemic — with a second option from Pfizer to follow shortly after.

22 Nov 2021

Using the contraceptive pill to reduce risk of type-2 diabetes in women with PCOS

In this interview, News-Medical speaks to Professor Weibke Arlt about her recent research into how the contraceptive pill affects type 2 diabetes in women with PCOS.

22 Nov 2021

Human Proteoform Project aims to define the entire collection of proteins in the body

Now that the Human Genome Project has officially wrapped, an international team of researchers will map the entire collection of proteins in the human body.

21 Nov 2021

A trio of proteins found to drive inflammation in psoriasis

About 7.5 million Americans suffer from psoriasis, an autoimmune disease that shows up as patches of red, inflamed skin and painful, scaly rashes. Although there are effective treatments for psoriasis, not everyone responds to these therapies - and for many, the relief is temporary.

21 Nov 2021

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

The inherited progressive disorder cystic fibrosis (CF) causes severe damage to the lungs, and other tissues in the body by affecting the cells that produce mucus, sweat, and digestive juices.

21 Nov 2021

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

People who received two doses of the Pfizer COVID-19 vaccine while on TNF inhibitors - a class of immunosuppressants used to treat rheumatoid arthritis and other autoimmune conditions - generated less powerful and shorter-lived antibodies against the virus that causes COVID-19 than healthy people and those on other kinds of immunosuppressants, according to a study by researchers at Washington University School of Medicine in St. Louis.

21 Nov 2021

Study reveals molecular architecture of fungal cell walls and structural responses to stress

In a new study published in Nature Communications, Associate Professor Tuo Wang and his research team from the Department of Chemistry at Louisiana State University revealed the molecular architecture of fungal cell walls and the structural responses to stresses, aiding the development of antifungal drugs targeting cell wall components.

21 Nov 2021

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

A group of scientists led by researchers from the RIKEN Center for Integrative Medical Sciences have discovered that B-cells, a type of immune cell, secrete the neurotransmitter GABA, and also found that the GABA secreted by the B-cells promoted the emergence of anti-inflammatory macrophages, blunting the body's cytotoxic T-cell-based response to tumors.

21 Nov 2021

UC researchers engineer new probiotic to target and break down cancer cell defenses

Bacteria generally have a bad reputation, as people first think of certain strains that can cause serious illnesses like pneumonia or meningitis. However, there are many helpful bacteria, known as probiotics, that assist the body in different ways.

21 Nov 2021

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Riluzole, a drug approved to treat amyotrophic lateral sclerosis (ALS), a disease affecting nerve cells controlling movement, could slow the gradual loss of a particular brain cell that occurs in Niemann-Pick disease type C1 (NPC1), a rare genetic disorder affecting children and adolescents, suggests a study in mice by scientists at the National Institutes of Health.

20 Nov 2021

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Researchers from Sorbonne Université have been reviewing papers exploring different anti-COVID-19 drugs.

19 Nov 2021

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Scientists recently gained insights into how vitamin D functions to reduce inflammation caused by immune cells that might be relevant to the responses during severe COVID-19. In a study jointly published by Purdue University and the National Institutes of Health, scientists do just that.

18 Nov 2021

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

Physicians at Washington University School of Medicine in St. Louis and Massachusetts General Hospital/Harvard Medical School in Boston have received a seven-year, $22 million grant from the National Institute of Allergy and Infectious Diseases of the National Institutes of Health to help lead a multicenter clinical trial evaluating whether a novel immunosuppressant can reduce the risk of organ rejection after a lung transplant.

18 Nov 2021

Drugs News and Research

Other molecules may have greater potential as cancer therapies than gold complex auranofin

Novel carbon dots exhibit antimicrobial activity against gram-negative bacteria

Examining the effects of malaria parasites on global health

Success of covid antiviral pills hinges on access to speedy and accurate tests

Using the contraceptive pill to reduce risk of type-2 diabetes in women with PCOS

Human Proteoform Project aims to define the entire collection of proteins in the body

A trio of proteins found to drive inflammation in psoriasis

Human lung airway-on-a-chip faithfully recapitulates cystic fibrosis pathology

People taking immunosuppressant produce weaker, shorter-lived antibodies after COVID-19 vaccination

Study reveals molecular architecture of fungal cell walls and structural responses to stress

GABA secreted by B-cells blunts the body's cytotoxic T-cell-based response to tumors

UC researchers engineer new probiotic to target and break down cancer cell defenses

Repurposed ALS drug could slow gradual brain cell loss in Niemann-Pick disease type C1

Comparing effectiveness of virus and patients-centered strategies to reduce COVID-19 mortality

Study reveals mechanism by which vitamin D reduces inflammation caused by immune cells

Researchers receive $22 million grant for clinical trial that aims to reduce lung transplant rejection

Antiretroviral drugs detected in drinking water

Experts develop a functional precision medicine approach to assign therapies to cancer patients

World Antimicrobial Awareness Week: An Interview with the World Health Organization

Scientists discover the genes used by bacteria to live within complex communities

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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