Immune System News and Research

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Sema4, Mount Sinai, Sanofi announce launch of new collaborative asthma study

Sema4, a patient-centered predictive health company, and the Mount Sinai Health System today announced the launch of a five-year collaborative study with Sanofi designed to provide new insights into the biological mechanisms and other factors implicated in asthma.

4 Dec 2018

Researchers find two connective tissue cells to be linked to worse prognosis of breast cancer

In certain forms of cancer, connective tissue forms around and within the tumor. One previously unproven theory is that there are several different types of connective tissue cells with different functions, which affect the development of the tumor in different ways.

4 Dec 2018

Customizing Genetically Engineered Models for Specific Research Applications

In this interview conducted at SfN 2018, Philip Dubé from Taconic Biosciences, goes into detail about genetically engineered models and their importance in understanding neurodegenerative diseases.

From Taconic Biosciences, Inc. 4 Dec 2018

Early gut bacterial colonization may reduce risk of developing eczema

Strains of a bacterium commonly found in skin infections may help to protect against eczema, according to new research in the British Journal of Dermatology.

4 Dec 2018

Clearer diagnosis of polio-like illness in young children

Johns Hopkins researchers have analyzed patient data from 45 cases of what they thought was acute flaccid myelitis, the polio-like outbreak occurring in U.S. children, and realized that only 75 percent of diagnosed cases were AFM.

4 Dec 2018

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

So-called CAR-T cell therapy is a promising option for treating around a fifth of patients with diffuse large B-cell lymphoma.

4 Dec 2018

International study increases group of lung cancer patients who may benefit from immunotherapy

The strategy for triggering the patient's own immune system to attack cancer, immunotherapy, is proving effective for more and more tumor types, although to varying degrees.

4 Dec 2018

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

A new article published today in The Lancet Oncology shows 39 percent of large B cell lymphoma patients treated with the chimeric antigen receptor T-cell therapy Yescarta remained in remission more than two years following therapy, and more than half of the patients treated remain alive.

4 Dec 2018

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

A gene mutation that is believed to have safeguarded some people in 14th century Europe from the bubonic plague today may be protecting HIV patients co-infected with hepatitis C from potentially fatal liver scarring, says a University of Cincinnati College of Medicine physician-scientist.

3 Dec 2018

Using nanocarrier-delivered microRNA to target sepsis

One in three patients who die in the U.S. dies of sepsis, according to the Centers for Disease Control and Prevention. It is one of the leading causes of death in intensive care units and, with an estimated price tag of $20 billion in 2011, the most expensive condition that hospitals treat.

3 Dec 2018

Transmission of gut bacteria from mother to baby is impacted in cesarean-born children

Together with colleagues from Sweden and Luxembourg, scientists from the Luxembourg Centre for Systems Biomedicine of the University of Luxembourg have observed that, during a natural vaginal birth, specific bacteria from the mother's gut are passed on to the baby and stimulate the baby's immune responses.

30 Nov 2018

Researchers reveal how some cancers trick healthy cells into protecting tumors

Many factors affect cancer treatment outcome, such as the size and location of the tumor, availability of effective treatments, and timing of intervention. But some cancers are so aggressive that outcome is poor, even after early diagnosis and chemotherapy.

30 Nov 2018

Triple combination cancer immunotherapy improves survival in mouse model of melanoma

Adoptive cell transfer is a promising cancer immunotherapy that involves isolating T cells from cancer patients that are capable of targeting their tumor, selecting the more active T cells and expanding those in the lab, and then transfusing them back into patients.

30 Nov 2018

Study points toward new strategies for managing organ transplantation

The human intestine may provide up to 10 percent of blood cells in circulation from its own reservoir of blood-forming stem cells, a surprising new study from researchers at Columbia University Vagelos College of Physicians and Surgeons has found.

30 Nov 2018

Liver immune cells contain inert HIV and are unlikely to reproduce infection, study reveals

In a proof-of-principle study, researchers at Johns Hopkins revealed that certain immune system cells found in the human liver, called liver macrophages, contain only inert HIV and aren't likely to reproduce infection on their own in HIV-infected people on long-term antiretroviral therapy.

30 Nov 2018

Researchers generate six antibodies to diagnose and treat Zika virus

Researchers have generated six Zika virus antibodies that could be used to test for and possibly treat a mosquito-borne disease that has infected more than 1.5 million people worldwide.

29 Nov 2018

ECDC and WHO release latest data on HIV epidemic in the European Region

The European Centre for Disease Prevention and Control and the WHO Regional Office for Europe release the latest data on the HIV epidemic in the European Region, marking the 30th anniversary of World AIDS Day.

29 Nov 2018

Researchers find how skin cancer cells avoid attack by the immune system

Researchers at the Mainz University Medical Center discovered a new signal pathway employed by skin cancer cells to avoid attack by the immune system. In an animal model and through analysis of human tissue samples, Dr. Toszka Bohn, Dr. Steffen Rapp and Professor Tobias Bopp were able to demonstrate the significant role played by a specific protein called ICER.

29 Nov 2018

FDA approves new drug for treatment of rare autoimmune disorder

The U.S. Food and Drug Administration today approved Firdapse (amifampridine) tablets for the treatment of Lambert-Eaton myasthenic syndrome (LEMS) in adults.

29 Nov 2018

New study solves longstanding mystery in innate immunity

UT Southwestern biochemist and Breakthrough Prize winner Dr. Zhijian "James" Chen's newest study answers a long-standing question in the field of innate immunity.

29 Nov 2018

Immune System News and Research

Sema4, Mount Sinai, Sanofi announce launch of new collaborative asthma study

Researchers find two connective tissue cells to be linked to worse prognosis of breast cancer

Customizing Genetically Engineered Models for Specific Research Applications

Early gut bacterial colonization may reduce risk of developing eczema

Clearer diagnosis of polio-like illness in young children

CAR-T cell therapy appears to be promising option for treating large B-cell lymphoma

International study increases group of lung cancer patients who may benefit from immunotherapy

Study: 39% of B cell lymphoma patients treated with CAR T therapy remain in remission

Genetic relic of the 'Black Death' may provide clues for treating fatal liver scarring

Using nanocarrier-delivered microRNA to target sepsis

Transmission of gut bacteria from mother to baby is impacted in cesarean-born children

Researchers reveal how some cancers trick healthy cells into protecting tumors

Triple combination cancer immunotherapy improves survival in mouse model of melanoma

Study points toward new strategies for managing organ transplantation

Liver immune cells contain inert HIV and are unlikely to reproduce infection, study reveals

Researchers generate six antibodies to diagnose and treat Zika virus

ECDC and WHO release latest data on HIV epidemic in the European Region

Researchers find how skin cancer cells avoid attack by the immune system

FDA approves new drug for treatment of rare autoimmune disorder

New study solves longstanding mystery in innate immunity

Understanding the DNA Damage Response in Innate Immunity eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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