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Researchers describe mechanism that sets stage for fate decision of T cells

After a pathogen infects the body, the immune system responds with a remarkable -- and remarkably complicated -- cascade of events.

14 Sep 2018

Researchers untangle mysteries of 'evil' protein in ER-positive breast cancer

Breast cancer is one of the most common cancers in the United States, striking 1 out of 8 women. About 80 percent of all breast cancers are estrogen receptor-positive, in which cancer growth is fueled by estrogen.

12 Sep 2018

Prenatal cannabinoid use can cause behavioral and neuronal deficits in male offspring

Taking cannabinoids during pregnancy can cause behavioral and neuronal deficits in adult male offspring, while females remain unaffected, says new research published in eLife.

12 Sep 2018

Protein involved in milk production appears to stimulate growth and spread of breast cancer

VCU Massey Cancer Center researchers have identified a protein involved in milk production that stimulates the growth and spread of breast cancer and could ultimately serve as a target for novel therapies to treat breast cancer.

12 Sep 2018

Mouse study suggests new therapeutic approach to treat heart failure

A heart attack triggers an acute inflammatory response, followed by resolution of inflammation and wound healing. A severe heart attack, however, can cause chronic and sustained inflammation that leads to heart failure and death.

10 Sep 2018

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

UCLA researchers have found that the extracellular matrix, the dense network of proteins and carbohydrates that surround a cell, can influence how cells move within the body by regulating their sugar consumption.

10 Sep 2018

Researchers develop new generation of pain medications

Researchers from Charité - Universitätsmedizin Berlin and the Zuse Institute Berlin have developed a new generation of pain medications.

7 Sep 2018

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Exelixis, Inc. today announced that the National Comprehensive Cancer Network updated its Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets.

7 Sep 2018

Study reinvestigates benefit of biomarker tests in certain breast cancer patients

The German Institute for Quality and Efficiency in Health Care reinvestigated the benefit of biomarker tests to support the decision for or against adjuvant systemic chemotherapy in certain breast cancer patients, that is, women with primary hormone receptor-positive, HER2/neu-negative breast cancer and 0 to 3 affected lymph nodes.

7 Sep 2018

Research team identifies new therapeutic target for castration-resistant prostate cancer

A collaborative research team has linked the development of castration-resistant prostate cancer and resistance to treatment to a lack of androgen receptor expression in prostate cancer cells, identifying a new therapeutic target for one of the deadliest forms of cancer among men.

7 Sep 2018

Endocrine Society announces winners of prestigious 2019 Laureate Awards

The Endocrine Society today announced it has chosen 13 leading endocrinologists as winners of its prestigious 2019 Laureate Awards, the top honors in the field.

6 Sep 2018

USC scientists develop new way to identify molecular markers of breast cancer tumors

A research team led by USC scientists has developed a new way to identify molecular markers of breast cancer tumors, a potentially life-saving breakthrough that could lead to better treatment for millions of women.

6 Sep 2018

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

Verastem, Inc., operating as Verastem Oncology, a biopharmaceutical company focused on developing and commercializing medicines to improve the survival and quality of life of cancer patients, today announced dosing of the first patient in a multicenter Phase I/II clinical trial at the Dana-Farber/Harvard Cancer Center of duvelisib in combination with venetoclax in patients with relapsed or refractory chronic lymphocytic leukemia or small lymphocytic lymphoma.

6 Sep 2018

Research finds why foods high in unsaturated fats protect against cardiovascular disease

Foods high in unsaturated fats may protect against cardiovascular disease, and new research published today in Nature Communications has uncovered why.

6 Sep 2018

Lymph node structural cells exert control over T cell responses

Until now, the study of the immune system has focused almost exclusively on white blood cells, and T cells in particular, as the body’s major infection fighters.

6 Sep 2018

New method may speed up development of novel drugs

Researchers of the University of Würzburg have developed a method that makes it possible to measure the activation of receptors in a very short time. This might speed up the development of new drugs.

6 Sep 2018

Hypertension drugs may be used to preserve memory of lupus patients

Researchers from The Feinstein Institute for Medical Research have discovered that the activation of brain cells called microglia likely contributes to the memory loss and other cognitive impairments suffered by many patients with systemic lupus erythematosus.

5 Sep 2018

Researchers discover how a protein complex safeguards against certain brain tumors

Researchers have discovered how a molecule can help prevent certain types of brain tumors by recognizing and 'disarming' harmful proteins that cause them.

5 Sep 2018

Study finds new clues to understand relapse in breast cancer

A large genomic analysis has linked certain DNA mutations to a high risk of relapse in estrogen receptor positive breast cancer, while other mutations were associated with better outcomes, according to researchers from Washington University School of Medicine in St. Louis, the Baylor College of Medicine and the University of British Columbia.

4 Sep 2018

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

New work from researchers at Columbia University Vagelos College of Physicians and Surgeons sheds light on how dopamine receptors signal within cells, opening the door for more targeted--and more tolerable--therapeutics to treat an array of neuropsychiatric disorders.

4 Sep 2018

Receptor News and Research

Researchers describe mechanism that sets stage for fate decision of T cells

Researchers untangle mysteries of 'evil' protein in ER-positive breast cancer

Prenatal cannabinoid use can cause behavioral and neuronal deficits in male offspring

Protein involved in milk production appears to stimulate growth and spread of breast cancer

Mouse study suggests new therapeutic approach to treat heart failure

Acute changes in extracellular matrix can trigger rapid change in cell’s metabolism

Researchers develop new generation of pain medications

NCCN updates Clinical Practice Guidelines to include new recommendations for CABOMETYX tablets

Study reinvestigates benefit of biomarker tests in certain breast cancer patients

Research team identifies new therapeutic target for castration-resistant prostate cancer

Endocrine Society announces winners of prestigious 2019 Laureate Awards

USC scientists develop new way to identify molecular markers of breast cancer tumors

Verastem doses first patient in Phase I/II clinical trial of duvelisib in combination with venetoclax

Research finds why foods high in unsaturated fats protect against cardiovascular disease

Lymph node structural cells exert control over T cell responses

New method may speed up development of novel drugs

Hypertension drugs may be used to preserve memory of lupus patients

Researchers discover how a protein complex safeguards against certain brain tumors

Study finds new clues to understand relapse in breast cancer

Dopamine receptor study opens door to targeted treatments for neuropsychiatric disorders

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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