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Study examines impact of managed care on stroke prevention surgery

Policymakers and economists often promote managed-care plans based on the assumption that they prevent the overuse of unnecessary surgical procedures or help steer patients to high-quality providers, compared to traditional fee-for-service insurance plans.

1 Jan 2009

Scientists genetically grab PTEN by the tail to curtail cancer

When researchers look inside human cancer cells for the whereabouts of an important tumor-suppressor, they often catch the protein playing hooky, lolling around in cellular broth instead of muscling its way out to the cells' membranes and foiling cancer growth.

1 Jan 2009

Schering-Plough announces European submission of fertility medicine Corifollitropin Alfa

Schering-Plough Corp. has announced that the European Medicines Agency (EMEA) has validated (accepted for review) its Marketing Authorization Application (MAA) for corifollitropin alfa, the company's experimental, sustained follicle stimulant (SFS).

1 Jan 2009

Researchers engineer pancreatic cell transplants to evade immune response

In a finding that could significantly influence the way type 1 diabetes is treated, researchers at Albert Einstein College of Medicine of Yeshiva University have developed a technique for transplanting insulin-producing pancreatic cells that causes only a minimal immune response in recipients.

1 Jan 2009

Laminin-111 shows potential for congenital muscular dystrophy

Current research suggests laminin, a protein that helps cells stick together, may lead to enhanced muscle repair in muscular dystrophy.

1 Jan 2009

New online tool for calculating colorectal cancer risk

A new online tool for calculating colorectal cancer risk in men and women age 50 or older was launched today, based on a new risk-assessment model developed by researchers at the National Cancer Institute (NCI), part of the National Institutes of Health.

1 Jan 2009

Medication errors among adults and children with cancer in the outpatient setting common

Seven percent of adults and 19 percent of children taking chemotherapy drugs in outpatient clinics or at home were given the wrong dose or experienced other mistakes involving their medications, according to a new study supported in part by HHS' Agency for Healthcare Research and Quality through its Centers for Education and Research on Therapeutics program.

1 Jan 2009

Lung cancer cells activate inflammation to induce metastasis

A research team from the University of California, San Diego School of Medicine has identified a protein produced by cancerous lung epithelial cells that enhances metastasis by stimulating the activity of inflammatory cells.

1 Jan 2009

Researchers assess safety of bismuth compounds for treatment peptic ulcer disease

The discovery of H. pylori in 1983 led to renewed interest in bismuth compounds, because these were found to successfully treat the infection in combination with antibiotics. However, in the 1970s bismuth salts, used at high doses for prolonged periods, were found to lead to neurotoxicity.

1 Jan 2009

Fewer deaths with preventive antibiotic use

Administering antibiotics as a preventive measure to patients in intensive care units (ICUs) increases their chances of survival.

1 Jan 2009

Few DNA repair gene variants associated with increased cancer risk

Variants of numerous DNA repair genes initially appeared to be statistically significantly associated with cancer risk in epidemiological studies.

1 Jan 2009

Arousal frequency in heart failure found to be a unique sleep problem

A study in the Jan. 1 issue of the journal Sleep demonstrates that the frequent arousals from sleep that occur in heart failure patients with central sleep apnea (CSA) may reflect the presence of another underlying arousal disorder rather than being a defensive mechanism to terminate apneas.

1 Jan 2009

What are protective effects of anti-ricin A-chain aptamer?

Ricin, a lectin from the castor bean plant Ricinus communis is considered one of the most potent plant toxins.

30 Dec 2008

Researchers identify common gene variant linked to high blood pressure

Researchers at the University of Maryland School of Medicine have identified a common gene variant that appears to influence people's risk of developing high blood pressure, according to the results of a study being published online Dec. 29, 2008 in the Proceedings of the National Academy of Sciences (PNAS).

30 Dec 2008

Discovery of molecule that targets brain tumors

UC Davis Cancer Center researchers report today the discovery of a molecule that targets glioblastoma, a highly deadly form of cancer.

30 Dec 2008

Cost effectiveness of spinal surgery examined

Back pain affects more than 80 percent of people and costs more than $100 billion annually in the U.S. But is the surgery cost effective?

30 Dec 2008

Study examines impact of managed care on stroke prevention surgery

30 Dec 2008

Scientists isolate genes that made 1918 flu lethal

By mixing and matching a contemporary flu virus with the "Spanish flu" - a virus that killed between 20 and 50 million people 90 years ago in history's most devastating outbreak of infectious disease - researchers have identified a set of three genes that helped underpin the extraordinary virulence of the 1918 virus.

30 Dec 2008

New study examines effects of chlorine gas disaster in South Carolina

A new study examining the aftereffects of a chlorine gas disaster in a South Carolina town gives larger metropolitan areas important insight into what to expect and how to prepare emergency response systems for an accidental or terrorist release of the potentially deadly gas.

30 Dec 2008