Drugs News and Research

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Public opinion is unified on lowering prescription drug prices. Why are leaders settling for less?

Democrats and Republicans are crystal clear in polls that they want government to be allowed to negotiate down high drug prices. Americans pay nearly three times as much for drugs as patients in dozens of other countries.

18 Nov 2021

Researchers identify compounds that tackle fungal infections in a new way

Current medications aren't particularly effective against fungi. The situation is becoming more challenging because these organisms are developing resistance to antimicrobial treatments, just as bacteria are.

17 Nov 2021

Scientists use advanced microscopes to delve deeper into protein degradation process

Proteins are the building blocks of all living things. A vast amount research takes place on how these proteins are made and what they do, from enzymes that carry out chemical reactions to messengers that transmit signals between cells.

17 Nov 2021

Scientists predict structures of eukaryotic protein complexes using AI

UT Southwestern and University of Washington researchers led an international team that used artificial intelligence (AI) and evolutionary analysis to produce 3D models of eukaryotic protein interactions.

17 Nov 2021

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

A recent study sed PBPK modeling to demonstrate the use of DEX PKs for the treatment of COVID-19 in patients with liver impairment.

17 Nov 2021

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

Researchers used advanced two-color fluorescence cross-correlation spectroscopy to demonstrate the interaction between human ACE2 and the S1 subunit of SARS-CoV-2 and SARS-CoV.

17 Nov 2021

What genes affect the COVID-19 gender imbalance?

Many studies have established that coronavirus disease 2019 (COVID-19) is more infective in men than women, and men are more at risk of severe disease. While some have suggested that behavioral differences could explain increased transmission to men, this does not explain the more morbid prognosis.

16 Nov 2021

Young adults with cancer may require different treatments than older patients

Not all tumors are alike. Young adults who are diagnosed with skin, colon, and other cancer types may require different treatments than older patients receive.

16 Nov 2021

Two genetic risk variants in Black individuals may exacerbate sepsis and COVID-19 severity

Two genetic risk variants that are carried by nearly 40 percent of Black individuals may exacerbate the severity of both sepsis and COVID-19, a team of researchers from the University of Pennsylvania's Perelman School of Medicine have found.

16 Nov 2021

SARS-CoV-2 replicates in human placenta with release of infectious viral particles

The current study analyzed the interaction of SARS-CoV-2 at the human maternal-fetal interface by using an advanced ex vivo model.

16 Nov 2021

As big pharma and hospitals battle over drug discounts, patients miss out on millions in benefits

In early July, as the covid-19 pandemic slammed rural America, the president of a small Kansas hospital sat down on a Friday afternoon and wrote the president of the United States to plead for help.

16 Nov 2021

Modeling the role of antivirals in suppressing the COVID-19 pandemic

A new study used an agent-based mathematical model to evaluate potential population impact on the widespread use of antiviral treatment for reducing viral load and hospitalization risk.

16 Nov 2021

Advanced tools for Glycobiology research

Drawing upon over 30-years’ experience of serving the glycobiology research community - AMSBIO has established a comprehensive portfolio of high-quality reagents including unique ranges of antibodies, lectins, enzymes, assay kits and standards, backed by in-depth technical support.

From AMS Biotechnology 16 Nov 2021

Immune response elicited by SARS-CoV-2 vaccines in infliximab and vedolizumab-treated patients with IBD

A recent study evaluates the immune responses elicited by COVID-19 vaccines in infliximab- or vedolizumab-treated IBD patients.

15 Nov 2021

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

A recent study investigates histone mimicry as a mechanism by SARS-CoV-2 for disrupting epigenetic regulation to evade host cell responses to infection.

15 Nov 2021

Promising results from Phase II REGEN-COV study

Initial results of the REGEN-COV Phase II study are presented.

15 Nov 2021

Common hypertension drug not effective in slowing down the progression of Alzheimer's disease

New research led by the University of Bristol, has shown the drug losartan, normally used to treat high blood pressure (hypertension), is not effective in slowing down the progression of Alzheimer's disease (AD) in people with mild-to-moderate disease after 12 months of treatment.

15 Nov 2021

Anticoagulants to prevent strokes do not provide adequate protection for hemodialysis patients

The anticoagulants currently used to prevent strokes in dialysis patients with atrial fibrillation do not provide adequate protection for this group.

15 Nov 2021

Posterior left pericardiotomy linked to prevention of atrial fibrillation after cardiac surgery

A simple surgical technique during cardiac surgery was associated with a 56 percent reduction in the incidence of an irregular heart rhythm known as atrial fibrillation that can lead to stroke, with no added risks or side effects, according to a new study by Weill Cornell Medicine and NewYork-Presbyterian investigators.

15 Nov 2021

Anti-platelet drug class fails to extend survival in moderately ill COVID-19 patients

A drug class that blocks the activity of blood platelets and prevents clotting—P2Y12 inhibitors—failed to extend survival or lessen disease severity in patients with COVID-19 who were hospitalized but had a relatively moderate case, a new study finds.

15 Nov 2021

Drugs News and Research

Public opinion is unified on lowering prescription drug prices. Why are leaders settling for less?

Researchers identify compounds that tackle fungal infections in a new way

Scientists use advanced microscopes to delve deeper into protein degradation process

Scientists predict structures of eukaryotic protein complexes using AI

Model simulations show no need for DEX dose adjustments in COVID-19 patients with liver disease

Interactions between SARS-CoV-2 S protein and ACE2 receptor using fluorescence correlation spectroscopy

What genes affect the COVID-19 gender imbalance?

Young adults with cancer may require different treatments than older patients

Two genetic risk variants in Black individuals may exacerbate sepsis and COVID-19 severity

SARS-CoV-2 replicates in human placenta with release of infectious viral particles

As big pharma and hospitals battle over drug discounts, patients miss out on millions in benefits

Modeling the role of antivirals in suppressing the COVID-19 pandemic

Advanced tools for Glycobiology research

Immune response elicited by SARS-CoV-2 vaccines in infliximab and vedolizumab-treated patients with IBD

Histone mimicry as a mechanism through which SARS-CoV-2 disrupts host cell epigenetic regulation

Promising results from Phase II REGEN-COV study

Common hypertension drug not effective in slowing down the progression of Alzheimer's disease

Anticoagulants to prevent strokes do not provide adequate protection for hemodialysis patients

Posterior left pericardiotomy linked to prevention of atrial fibrillation after cardiac surgery

Anti-platelet drug class fails to extend survival in moderately ill COVID-19 patients

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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