Kidney News and Research

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Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

Novartis announced new data today showing a significant improvement in both recurrence-free survival and overall survival for patients taking Gleevec® (imatinib mesylate)* tablets for three years after surgery to remove KIT (CD117)-positive gastrointestinal stromal tumors (KIT+ GIST) compared to one year of treatment. These data will be presented at the 47th American Society of Clinical Oncology (ASCO) plenary session on Sunday, June 5.

6 Jun 2011

New E. coli outbreak alarms Europe

An Escherichia coli (E. coli) outbreak of disease in Germany has left 22 people dead and it is alarming populations across Europe.

5 Jun 2011

Scientists find way to protect kidney from cancer drug toxicity

Scientists may have a way to make the powerful cancer drug cisplatin less toxic to the kidneys and more effective against some cancers.

4 Jun 2011

Preliminary data from Ion PGM sequencer reveals German E. coli outbreak is a new hybrid strain

Life Technologies Corporation today announced that preliminary data from DNA sequencing performed in cooperation with the University Hospital Muenster, Germany, on the Ion Personal Genome Machine strongly suggests that the bacterium at the root of the deadly outbreak in Germany is a new hybrid type of pathogenic E. coli strains.

4 Jun 2011

Peptide vaccine, Interleukin-2 show promise for patients with metastatic melanoma

For patients with advanced melanoma, which is the most lethal type of skin cancer, the results of a large clinical trial show that a vaccine combined with the immune-boosting drug Interleukin-2 can improve response rate and progression-free survival.

4 Jun 2011

European E. coli strain never seen before in humans, scientists say

The food safety office of the WHO on Thursday announced that the bacterium responsible for the E. coli outbreak in Europe is a strain never seen before in humans and could mean "the infection could prove unusually difficult to bring under control," Nature News reports.

4 Jun 2011

Battelle, Perma-Fix sign exclusive option agreement to make medical isotopes

Perma-Fix Environmental Services, Inc. today announced it has signed an exclusive option agreement with Battelle, which operates Pacific Northwest National Laboratory for the U.S. Department of Energy, to license technology from PNNL for use with Perma-Fix's proprietary process to safely and cost-effectively produce Molybdenum-99 (Mo-99), which is used to make Technetium 99m (Tc-99m).

4 Jun 2011

Ipilimumab and bevacizumab drugs effective in treating metatastic melanoma

A duo of drugs, each targeting a prime survival strategy of tumors, can be safely administered and are potentially more effective than either drug alone for advanced, inoperable melanomas, according to a phase 1 clinical trial led by Dana-Farber Cancer Institute investigators.

4 Jun 2011

Angiotensin receptor blockers do not increase risk of cancer: FDA

The U.S. Food and Drug Administration today announced that a group of medications used to control high blood pressure, called angiotensin receptor blockers (ARBs), do not increase the risk of developing cancer in patients using the medications.

3 Jun 2011

Final analysis of AVEO's tivozanib Phase 2 trial on kidney cancer patients presented at ASCO 2011

AVEO Pharmaceuticals, Inc., today announced data from the final analysis of its Phase 2 randomized discontinuation trial evaluating tivozanib, its lead product candidate designed to optimally block the VEGF pathway by inhibiting all three VEGF receptors, in patients with advanced renal cell carcinoma.

2 Jun 2011

Lymphocyte count serves as simple and effective prognostic indicator in renal cell carcinoma

Each year, kidney cancer is diagnosed in nearly 60,000 people in the U.S. Many of these patients undergo surgery to remove the affected kidney, but this procedure can be risky for the elderly and those who have other health problems. Unfortunately, the prognosis of kidney cancer patients often cannot be determined until tumor samples are surgically removed and evaluated.

2 Jun 2011

Nighttime heart and lung transplants do not affect patient survival

Despite concerns that surgeon fatigue is leading to dangerous complications for patients and data showing worse outcomes for many patients who undergo surgery at night, new Johns Hopkins research suggests that — in the case of heart and lung transplants — time of day has no affect on patient survival.

1 Jun 2011

HbA1c glucose monitoring test not effective for diagnosing diabetes patients with kidney failure

The gold standard long-term glucose monitoring test for patients with diabetes proved to be of limited value in dialysis patients, according to a new study at Wake Forest Baptist Medical Center.

1 Jun 2011

Eculizumab effective for treating hemolytic-uremic syndrome from EHEC

In the online version of the New England Journal of Medicine, physicians and scientists in Heidelberg, Montreal, and Paris reported on the successful treatment of three young children who were suffering from a severe hemolytic-uremic syndrome after an infection with enterohemorrhagic Escherichia coli.

1 Jun 2011

SQI Diagnostics reports net loss of $1,874,000 for second quarter 2011

SQI Diagnostics Inc., a life sciences company that develops and commercializes proprietary multiplexing technologies and products for advanced microarray diagnostics, today announced its financial and operational results for the second quarter ended March 31, 2011.

30 May 2011

Pre-implantation genetic diagnosis can avoid mother to child transmission of mtDNA disorders

Dutch researchers have developed a test which predicts which mothers at risk of passing on mitochondrial genetic disease to their children are likely to have a healthy baby.

30 May 2011

Lipidomic profiling can lead to better and earlier prediction of major diseases

Studying the genetic make-up of different varieties of lipids in the blood plasma of an individual can lead to a better and earlier prediction of diseases such as diabetes, atherosclerosis, and heart disease, two researchers will tell the annual conference of the European Society of Human Genetics today.

30 May 2011

New imaging method using fluorescent nanotubes can peer clearly into living mouse's innards

Developing drugs to combat or cure human disease often involves a phase of testing with mice, so being able to peer clearly into a living mouse's innards has real value.

30 May 2011

ASH announces approval of official health care taxonomy code for Designated Specialists

Today the American Society of Hypertension, Inc. (ASH) and the ASH Specialist Program Inc. announced the approval of an official health care taxonomy code for Designated Specialists in Clinical Hypertension from the American Medical Association National Uniform Claims Committee.

27 May 2011

Tacrolimus prevents breast cancer growth in pre-clinical studies

Tacrolimus, a drug that is commonly used to prevent organ transplantation rejection, inhibits breast cancer growth in pre-clinical studies. The finding from UNC scientists was reported in the May 26th PLoS ONE.

27 May 2011

Kidney News and Research

Gleevec shows significant overall survival benefit for patients w/ GIST after 3 years of adjuvant treatment vs. 1 year

New E. coli outbreak alarms Europe

Scientists find way to protect kidney from cancer drug toxicity

Preliminary data from Ion PGM sequencer reveals German E. coli outbreak is a new hybrid strain

Peptide vaccine, Interleukin-2 show promise for patients with metastatic melanoma

European E. coli strain never seen before in humans, scientists say

Battelle, Perma-Fix sign exclusive option agreement to make medical isotopes

Ipilimumab and bevacizumab drugs effective in treating metatastic melanoma

Angiotensin receptor blockers do not increase risk of cancer: FDA

Final analysis of AVEO's tivozanib Phase 2 trial on kidney cancer patients presented at ASCO 2011

Lymphocyte count serves as simple and effective prognostic indicator in renal cell carcinoma

Nighttime heart and lung transplants do not affect patient survival

HbA1c glucose monitoring test not effective for diagnosing diabetes patients with kidney failure

Eculizumab effective for treating hemolytic-uremic syndrome from EHEC

SQI Diagnostics reports net loss of $1,874,000 for second quarter 2011

Pre-implantation genetic diagnosis can avoid mother to child transmission of mtDNA disorders

Lipidomic profiling can lead to better and earlier prediction of major diseases

New imaging method using fluorescent nanotubes can peer clearly into living mouse's innards

ASH announces approval of official health care taxonomy code for Designated Specialists

Tacrolimus prevents breast cancer growth in pre-clinical studies

Free guide - Everything about renal proximal tubule cells eBook

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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