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Proteins are complex molecules that are made up of amino acids. They can be found in every cell in the body, and carry out vital processes that keep human beings alive. Mutations in proteins can lead to a multitude of diseases, the most common being cancer.

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

In a recent study posted to the bioRxiv* preprint server, researchers in China demonstrated the efficacy of three messenger ribonucleic acid (mRNA) technology-based Monkeypox virus (MPXV) vaccines in combating a lethal Vaccinia virus (VACV) challenge in mice models.

22 Nov 2022

Unique resource for identifying new biomarkers of environmental exposures in early life

Researchers now have a unique resource for identifying new biomarkers of environmental exposures in early life and understanding their health effects.

22 Nov 2022

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Zika virus (ZIKV) infection is a potentially teratogenic illness, causing up to one in seven infants born to infected mothers to suffer neurodevelopmental deficits. A new study published in the journal Cell shows that some mothers escape injury to their babies because they develop a highly potent neutralizing antibody.

22 Nov 2022

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

A novel mAb against the SARS-CoV-2 RBD through a hybridoma technique, followed by chimerization and expression in plants.

22 Nov 2022

Scientists move a step closer to advancing personalized cancer treatment

In a step likely to advance personalized cancer treatment, scientists have for the first time shown in patients that levels of biomarkers are not enough to tell which patients are likely to respond best to immunotherapy.

22 Nov 2022

Study shows how HIV protein permanently alters immune cells

Though antiretroviral therapy has made HIV a manageable disease, people living with HIV often suffer from chronic inflammation.

22 Nov 2022

UVA Health researchers develop new tool to advance genomics and disease research

UVA Health researchers have developed an important new tool to help scientists sort signal from noise as they probe the genetic causes of cancer and other diseases.

22 Nov 2022

SARS-CoV-2 seroprevalence in domestic cats has increased over time

Researchers evaluated severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) transmission among domestic cats in the United Kingdom (UK).

22 Nov 2022

Discovery could lead to new mantle cell lymphoma drugs

A form of blood cancer known as mantle cell lymphoma is critically dependent on a protein that coordinates gene expression, such that blocking its activity with an experimental drug dramatically slows the growth of this lymphoma in preclinical tests, according to a study from Weill Cornell Medicine researchers.

22 Nov 2022

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

In a recent study, researchers used proteomic analysis to identify novel immune cell phenotypes associated with severe coronavirus disease 2019 (COVID-19).

22 Nov 2022

Previously unknown links between genetic factors in ASD identified

In a new study published today in Cell Reports, researchers from the Donald K. Johnson Eye Institute (DKJEI), part of the Krembil Research Institute at University Health Network, have identified previously unknown connections between genetic factors in Autism Spectrum Disorder (ASD).

22 Nov 2022

Study shows sylvatic origin of chikungunya virus transmission among nonhuman primates of Myanmar

Researchers investigated the potential exposure of peri-urban non-human primates (NHPs) residing near Yangon to arboviruses that have raised health concerns.

22 Nov 2022

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

We speak to Matthew Dunne, Director for Drug Discovery at Micreos Pharmaceuticals, about the importance of creating new targeted antibacterial products.

22 Nov 2022

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

Researchers explored active and passive vaccination among children against respiratory syncytial virus (RSV).

22 Nov 2022

The biological properties of the SARS-CoV-2 E protein in the context of HIV-1

Researchers assessed the effectiveness of SARS-CoV and SARS-CoV-2 envelope proteins against HIV-1.

22 Nov 2022

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

In a recent study published in the journal Advanced Science, researchers developed molecularly imprinted nanoparticles (nanoMIPs) with broad-spectrum activity against lethal viruses.

21 Nov 2022

Rice bioengineer receives support for brain cancer research

Kevin McHugh, an assistant professor of bioengineering at Rice University's George R. Brown School of Engineering, has earned a Distinguished Scientist Award for 2022 from The Sontag Foundation, which helps launch the careers of scientists expected to make a significant impact in the fight against brain cancer.

21 Nov 2022

New studies improve understanding of the genetic factors that protect people against COVID-19

Two recent papers by Brazilian researchers have contributed to the scientific understanding of the genetic factors that protect people against infection by SARS-CoV-2 or prevent progression to severe COVID-19.

21 Nov 2022

Study finds no benefits from angiotensin receptor blocker treatment for COVID-19

In a recent study published in the BMJ, researchers conducted a phase three, multicenter, randomized controlled trial to evaluate the effect of using angiotensin receptor blockers that disrupt the renin-angiotensin system on the clinical outcomes of individuals with coronavirus disease 2019 (COVID-19).

21 Nov 2022

KEMEPHY diet may be an effective dietary pattern for athletes

Scientists have characterized the effects of the ketogenic Mediterranean diet with phytoextracts on gut microbiota composition in athletes. The study by researchers in Italy and Spain is published in the journal Frontiers in Nutrition.

21 Nov 2022

Protein News and Research

Further Reading

Novel mRNA vaccines encoding Monkeypox virus proteins show promise in preclinical studies

Unique resource for identifying new biomarkers of environmental exposures in early life

Ultrapotent IgM antibodies isolated from a pregnant woman with Zika virus show promise as an immunotherapy

Plant-based monoclonal antibody increases potency of antibody cocktail against SARS-CoV-2 Omicron variant

Scientists move a step closer to advancing personalized cancer treatment

Study shows how HIV protein permanently alters immune cells

UVA Health researchers develop new tool to advance genomics and disease research

SARS-CoV-2 seroprevalence in domestic cats has increased over time

Discovery could lead to new mantle cell lymphoma drugs

Proteomic analysis identifies novel phenotypes associated with COVID-19 severity in circulating immune cells

Previously unknown links between genetic factors in ASD identified

Study shows sylvatic origin of chikungunya virus transmission among nonhuman primates of Myanmar

Creating New Targeted Antibacterial Products to Help Tackle Antimicrobial Resistance

Approved and developing passive and active immunizations against respiratory syncytial virus in childhood and pregnancy

The biological properties of the SARS-CoV-2 E protein in the context of HIV-1

Potent hypervalent nanoparticles against HIV, Lassa and SARS-CoV-2 variants

Rice bioengineer receives support for brain cancer research

New studies improve understanding of the genetic factors that protect people against COVID-19

Study finds no benefits from angiotensin receptor blocker treatment for COVID-19

KEMEPHY diet may be an effective dietary pattern for athletes

Editorial Focus eBook - Proteomics eBook

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