Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Simple formula that will enable anesthesiologists to predict blood needs in heart surgery

Duke University Medical Center researchers have developed a simple formula that will enable anesthesiologists to predict, based on individual patient characteristics, how much blood to have on hand in the operating room prior to coronary artery bypass surgery.

3 May 2006

The 30-year natural history of type 1 diabetes complications

...while cases of premature death and a few other complications have declined, rates of other serious diabetes-related disorders such as heart and eye disease have not improved over the past 25 to 30 years.

3 May 2006

Kidney patients warned away from potassium

Many kidney failure patients are increasing their chance of nerve damage in their legs and feet by simply having too much potassium in their diet, according to research carried out by the University of New South Wales (UNSW), the Prince of Wales Medical Research Institute (POWMRI) and the Prince of Wales Hospital.

2 May 2006

Combinatorial approach found to reverse the onset of type 1 diabetes

A major finding, which represents an important step toward a potential cure for type 1 (insulin-dependent) diabetes, has been made by a research team at the La Jolla Institute for Allergy & Immunology (LIAI). The team, led by Matthias von Herrath, M.D., an internationally recognized expert on the molecular basis of type 1 diabetes, used a combinatorial treatment approach in laboratory mice and found it reversed recent onset type 1 diabetes in the majority of animals tested.

28 Apr 2006

New technique to speed discovery of drug targets in chemical genetics

Researchers at Fox Chase Cancer Center have developed a new technique to speed discovery of drug targets in chemical genetics. Fox Chase researcher Jeffrey R. Peterson, Ph.D., and his colleagues describe a new way to swiftly find the proteins targeted by small molecule inhibitors during high-throughput screening (HTS) experiments. The new work offers a critical solution to a common stumbling block in this booming field of drug discovery.

26 Apr 2006

Forsenol reduces tablet burden on end stage renal disease patients with hyperphospatemia

According to data presented at the National Kidney Foundation's (NKF) 2006 clinical meeting in Chicago, IL, a conversion to the non-calcium phosphate binder FOSRENOL (lanthanum carbonate) from other phosphate binder therapies provides continued mean serum phosphorus control for end-stage renal disease (ESRD) patients with hyperphosphatemia, while significantly reducing their daily tablet burden and the total daily dose of phosphate binder medication.

26 Apr 2006

Study shows drugs work differently in the brains of men and women

A Johns Hopkins discovery could lead to tailored treatments for drug abuse and neurological diseases after providing what is believed to be the first evidence in people that amphetamines have a greater effect on men's brains than women's.

24 Apr 2006

Kidney treatments may be improved with new understanding of cell death mechanism

Finding how two proteins conspire to get kidney cells to self-destruct when oxygen supplies are low may one day improve dismal mortality rates for ischemic renal failure, researchers say.

23 Apr 2006

Drug combo might beat type 1 diabetes

Scientists in California have developed a cocktail of drugs which can reverse diabetes and say the discovery is an important step towards a potential cure.

23 Apr 2006

New inhaled diabetic drug too costly for the NHS

The National Health Service in the UK seems to be staggering from one crisis to another and now another row has broken out over a new treatment for diabetes.

19 Apr 2006

$6.5 million in funding to support innovations in the delivery of health care to New Yorkers

The New York State Health Department has announced the creation of six regional demonstration projects totaling $6.5 million in grant awards to help address the complex health care needs of Medicaid recipients with chronic illness or at-risk for disease.

19 Apr 2006

White girls become less depressed as they age while black girls continue feeling the same

Franko and her associates surveyed more than two thousand girls and young women of both ethnicities and concluded that the depression rate in Caucasian females drops over time, while it remains steady in their African-American counterparts.

19 Apr 2006

Study shows mercury amalgam fillings pose no health concerns for children

There were no statistically significant differences in neuropsychological and neurobehavioral effects among children whose dental caries were treated with mercury amalgam fillings and those treated with a composite dental restorative material

18 Apr 2006

Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

Fast-acting artificial insulin drugs work just as well as regular human insulin, but it's unclear how they could affect the health of people with diabetes over the long run, according to a new review of recent studies.

18 Apr 2006

Only 43 percent of older people with diabetes receive medicines that could protect their heart and kidneys

...despite the fact that virtually all of them could benefit from those drugs, a new University of Michigan study finds. And even among those with the most to gain from the medicines, the rate of use barely reaches 53 percent.

18 Apr 2006

Diabetes: Translating the chronic care model into the community

Educating people with diabetes in a primary-care setting with sustained, comprehensive intervention resulted in significant improvement in disease management and overall health, according to a study published in the current issue of Diabetes Care, a journal of the American Diabetes Association (ADA).

16 Apr 2006

Approval of integrated insulin pump and continuous glucose system a significant step towards artificial pancreas technology

The Juvenile Diabetes Research Foundation (JDRF) has said that the federal government's approval of an insulin pump that also provides real-time, continuous glucose monitoring is a significant step on the path to the development of an artificial pancreas, with the potential to significantly improve diabetes care and lower the risk of complications.

13 Apr 2006

Swine disease in China caused toxic shock syndrome

A large and deadly outbreak of Streptococcus suis disease, in Sichuan province in China last year alarmed health officials worldwide and now scientists from the Chinese Academy of Sciences, the Chinese Center for Disease Control and Prevention, and other Chinese institutions have published the first scientific details of the outbreak.

12 Apr 2006

Scientists reconstruct Darwinian evolution to explain 'irreducible complexity'

Using new techniques for resurrecting ancient genes, scientists have for the first time reconstructed the Darwinian evolution of an apparently "irreducibly complex" molecular system.

11 Apr 2006

Scientists use corrective gene to block a protein in the kidneys that triggers high blood pressure

Nearly one-third of American adults have high blood pressure, a major cause of heart attacks, strokes and kidney failure. But a new technique tested at the University of Florida could prove to be a long-term way to treat the disorder in humans, researchers say.

11 Apr 2006

Nephrology News and Research

Further Reading

Simple formula that will enable anesthesiologists to predict blood needs in heart surgery

The 30-year natural history of type 1 diabetes complications

Kidney patients warned away from potassium

Combinatorial approach found to reverse the onset of type 1 diabetes

New technique to speed discovery of drug targets in chemical genetics

Forsenol reduces tablet burden on end stage renal disease patients with hyperphospatemia

Study shows drugs work differently in the brains of men and women

Kidney treatments may be improved with new understanding of cell death mechanism

Drug combo might beat type 1 diabetes

New inhaled diabetic drug too costly for the NHS

$6.5 million in funding to support innovations in the delivery of health care to New Yorkers

White girls become less depressed as they age while black girls continue feeling the same

Study shows mercury amalgam fillings pose no health concerns for children

Short acting insulin analogues versus regular human insulin in patients with diabetes mellitus

Only 43 percent of older people with diabetes receive medicines that could protect their heart and kidneys

Diabetes: Translating the chronic care model into the community

Approval of integrated insulin pump and continuous glucose system a significant step towards artificial pancreas technology

Swine disease in China caused toxic shock syndrome

Scientists reconstruct Darwinian evolution to explain 'irreducible complexity'

Scientists use corrective gene to block a protein in the kidneys that triggers high blood pressure

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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