Cartilage News and Research

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Cartilage is a stiff yet flexible connective tissue found in many areas in the bodies of humans and other animals, including the joints between bones, the rib cage, the ear, the nose, the elbow, the knee, the ankle, the bronchial tubes and the intervertebral discs.

Ampio Pharmaceuticals receives FDA IND approval to start clinical trial of Ampion

Ampio Pharmaceuticals, Inc. today announced FDA acceptance of its IND and the treatment of the first fifteen (15) patients in its clinical trial using Ampion™ to treat osteoarthritis of the knee.

2 Apr 2013

Adding lubricin to fluid in our joints may prevent osteoarthritis, researchers find

Think new discoveries are the bee's knees? This one is even better -- this research out of Rhode Island Hospital is the mice's knees. Researchers have found that adding lubricin, a protein that our bodies naturally produce, to the fluid in our joints may reduce the risk of or even prevent osteoarthritis.

25 Mar 2013

OATS treatment for knee defects may not allow military patients to return to full duty, say researchers

Treatment of large cartilage knee defects with an allograft osteoarticular transplant may not allow some military personnel to return to full active duty status, say researchers presenting their work at the American Orthopaedic Society for Sports Medicine's Specialty Day in Chicago, IL.

25 Mar 2013

Adult stem cells improve cartilage repair

Using adult stem cells is a good way of culturing better-quality cartilage to repair worn hips and knees. New cartilage that has good properties can be grown in particular by cultivating adult stem cells in combination with a small quantity of cells from the patient's own cartilage.

21 Mar 2013

Multipotent stem cells in deer antler may have regenerative uses in veterinary medicine

A team of researchers in Seoul, Korea have reported finding evidence that deer antlers - unique in that they regenerate annually - contain multipotent stem cells that could be useful for tissue regeneration in veterinary medicine.

20 Mar 2013

Specialists offer new technique for nostril reconstruction

The skin cancer growing on Carolyn Bohlmann's nose was not a very aggressive variety. But it was deep and located right on her nostril. The tricky part was not so much removing it - MOHS surgery, the procedure Bohlmann had, is a fairly common outpatient procedure.

14 Mar 2013

Ampio to initiate dose escalation run-in study for treatment of knee osteoarthritis

Ampio Pharmaceuticals, Inc. announced today that it's Phase III clinical study of Ampion™ for the treatment for osteoarthritis of the knee will include a dose-escalation run-in study as recommended by the FDA.

25 Feb 2013

Researchers use 3D printing and injectable gels to create bioengineered ears

Physicians at Weill Cornell Medical College and biomedical engineers at Cornell University have succeeded in building a facsimile of a living human ear that looks and acts like a natural ear. Researchers believe their bioengineering method will finally succeed in the long quest by scientists and physicians to provide normal looking "new" ears to thousands of children born with a congenital ear deformity.

22 Feb 2013

Oblique split graft technique avoids rhinoplasty warp

A novel graft technique may reduce the risk of costal cartilage graft warping in patients undergoing septorhinoplasty for saddle nose deformity with depleted source, Turkish surgeons say.

19 Feb 2013

Platelet-rich plasma holds great promise in treating knee OA

A study by researchers from Hospital for Special Surgery has shown that platelet-rich plasma (PRP) holds great promise for treating patients with knee osteoarthritis.

13 Feb 2013

ACL injuries on the rise among young athletes

Until a child's bones have fully matured (in girls, typically by age 14; in boys, age 16), an injury to the anterior cruciate ligament (ACL)-the primary, stabilizing ligament of the knee joint-requires special consideration, treatment and care to ensure appropriate healing and to prevent long-term complications.

7 Feb 2013

Cartilage tympanoplasty can be performed successfully in 95% of young children

Cartilage tympanoplasty can be performed successfully in 95 percent of young children when appropriate conditions exist, according to a study in the February 2013 issue of Otolaryngology-Head and Neck Surgery.

5 Feb 2013

New noninvasive method for early detection of osteoarthritis may be on its way

A new, noninvasive, and low-cost method for the early detection and monitoring of osteoarthritis (arthritis caused by wear and tear) may be on its way, thanks to research by UC Santa Barbara scientists from the Department of Chemical Engineering and the Department of Materials.

31 Jan 2013

Sanofi introduces LeGoo gel to temporarily stop blood flow during cardiovascular surgery

Sanofi US announced the commercial launch of LeGoo, a biopolymer gel that allows surgeons to temporarily stop blood flow during surgery without the use of clamps, elastic loops or other conventional occlusion devices, which may increase risk of trauma to blood vessels.

30 Jan 2013

Researchers study innovative stem cell drug for treating localized cartilage damage

Rush University Medical Center is conducting the nation's first clinical study of an innovative stem cell drug, Cartistem, to repair knee cartilage damaged by aging, trauma or degenerative diseases such as osteoarthritis.

25 Jan 2013

Knee cartilage repair success with new biomaterial

In a small study, researchers reported increased healthy tissue growth after surgical repair of damaged cartilage if they put a “hydrogel” scaffolding into the wound to support and nourish the healing process. The squishy hydrogel material was implanted in 15 patients during standard microfracture surgery, in which tiny holes are punched in a bone near the injured cartilage. The holes stimulate patients’ own specialized stem cells to emerge from bone marrow and grow new cartilage atop the bone.

15 Jan 2013

Vitamin D claims for knee osteoarthritis questioned

The benefit of taking vitamin D supplements for the treatment of knee osteoarthritis has been challenged in a study published in JAMA.

14 Jan 2013

Graft recommendation bursts onto eardrum repair scene

Researchers say that a 0.2-mm partial thickness graft is optimal for reconstruction of subtotal tympanic membrane perforation.

14 Jan 2013

New Wiley handbook offers well-designed approach to imaging musculoskeletal trauma

Imaging Musculoskeletal Trauma: A Handbook for the Clinic, published by Wiley, offers a well-designed approach to imaging musculoskeletal trauma.

3 Jan 2013

Scientists identify molecular mechanism central to development of osteoarthritis pain

Researchers at Rush University Medical Center, in collaboration with researchers at Northwestern University, have identified a molecular mechanism central to the development of osteoarthritis (OA) pain, a finding that could have major implications for future treatment of this often-debilitating condition.

28 Dec 2012