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Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

Scientists and physicians at University of California San Diego School of Medicine, working with colleagues at the U.S. Navy Medical Research Center - Biological Defense Research Directorate, Texas A&M University, a San Diego-based biotech and elsewhere, have successfully used an experimental therapy involving bacteriophages -- viruses that target and consume specific strains of bacteria -- to treat a patient near death from a multidrug-resistant bacterium.

25 Apr 2017

Combination of genetics and experience gives each individual a unique sense of smell, study finds

Researchers from the Wellcome Trust Sanger Institute and their collaborators have shown that receptors in the noses of mice exposed to certain smells during life are different to genetically similar mice that lived without those smells.

25 Apr 2017

Brown University researchers develop new multi-reaction catalyst

Brown University researchers have developed a new composite catalyst that can perform four separate chemical reactions in sequential order and in one container to produce compounds useful in making a wide range of pharmaceutical products.

25 Apr 2017

Study reveals potential therapeutic target for kidney fibrosis

When the kidneys - vital organs for filtering the body's entire blood supply - become injured, it can set in motion an unfortunate chain of events that leads to a decline in health.

20 Apr 2017

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

A vaccine targeting cytomegalovirus (CMV) antigen pp65, combined with high-dose chemotherapy (temozolomide), improved both progression-free survival and overall survival for a small group of glioblastoma (GBM) patients.

17 Apr 2017

Complex, conflicting state laws pose barriers to medical decision-making, study reveals

A patchwork of state laws creates a labyrinth that can make it confusing to navigate incapacitated patients' medical wishes.

13 Apr 2017

Study finds unnecessary referrals, testing in patients treated at hospital-based primary practices

Patients with common conditions such as back pain, headaches and upper respiratory infections are more likely to receive tests and services of uncertain or little diagnostic or therapeutic benefit--so-called low-value care--when they seek treatment in primary care clinics located at hospitals rather than at community-based primary care clinics, according to a nationwide study led by researchers at Harvard Medical School and the David Geffen School of Medicine at UCLA.

10 Apr 2017

Case Western Reserve and Q2 Pharma partner to develop antivirulence agents that disarm superbugs

Case Western Reserve University and Q2 Pharma Ltd., an Israeli biopharmaceutical company, have signed a two-year option to license small molecule, antivirulence technology to potentially treat bacterial infections such as methicillin-resistant staphylococcus aureus (MRSA), the first known scientific effort of its kind.

31 Mar 2017

Article focuses on microwave-induced bismuth salts-mediated synthesis of useful organic compounds

Bismuth salts are used as medicinally active ingredients for the past many years due to their minimum toxicity and side effects

25 Mar 2017

TSRI chemists devise versatile molecule-building tool for creating new drugs and chemical products

Chemists at The Scripps Research Institute have devised a versatile molecule-building tool for creating new drugs and other chemical products.

9 Mar 2017

Researchers to examine link between zinc deficiency, Hedgehog, and prostate cancer

Experiments show that Hedgehog signaling - a chain of molecular events critical in embryonic development - creates conditions beneficial to the unregulated cell growth associated with cancer in adults.

28 Feb 2017

Scientists unravel novel protein catalysts that can direct biosynthesis of hapalindole-type alkaloids

Alkaloids are natural nitrogen-containing compounds produced by plants and microbes. These molecules, such as morphine and quinine, are important human medicines.

22 Feb 2017

New approach could make organometallic catalysis applicable for therapy or diagnostics

A gold catalyst can be delivered to a target organ in a higher organism where it performs a chemical transformation visualized by bioimaging.

17 Feb 2017

Scientists managed to produce large quantities of promising natural substance

Once they can synthesise molecules of active natural substances, scientists will be able to harness nature’s medicine cabinet for the drugs of the future.

14 Feb 2017

UNC scientists confirm and clarify key molecular details of nucleotide excision repair

Day in and day out, in our bodies, the DNA in cells is damaged for a variety of reasons, and thus intercellular DNA-repair systems are fundamental to the maintenance of life.

8 Feb 2017

Exposure to heightened air pollution increases risk of Type 2 diabetes in obese Latino children

Latino children who live in areas with higher levels of air pollution have a heightened risk of developing Type 2 diabetes, according to a new USC-led study.

7 Feb 2017

Advances in prosthetic knee technology

These prosthetics are a big change from traditional models. The knees are designed with a programmable computer that is built in to the joint. This battery powered technology continuously controls both the swing and the stance phase of the prosthetic through real time data that the computer receives from its built-in sensors.

6 Feb 2017

Catalyst News and Research

Researchers use novel phage therapy to treat patient infected with multidrug-resistant bacterium

Combination of genetics and experience gives each individual a unique sense of smell, study finds

Brown University researchers develop new multi-reaction catalyst

Study reveals potential therapeutic target for kidney fibrosis

Vaccine-chemotherapy combination may improve survival for glioblastoma patients

Complex, conflicting state laws pose barriers to medical decision-making, study reveals

Study finds unnecessary referrals, testing in patients treated at hospital-based primary practices

Case Western Reserve and Q2 Pharma partner to develop antivirulence agents that disarm superbugs

Article focuses on microwave-induced bismuth salts-mediated synthesis of useful organic compounds

TSRI chemists devise versatile molecule-building tool for creating new drugs and chemical products

Researchers to examine link between zinc deficiency, Hedgehog, and prostate cancer

Scientists unravel novel protein catalysts that can direct biosynthesis of hapalindole-type alkaloids

New approach could make organometallic catalysis applicable for therapy or diagnostics

Scientists managed to produce large quantities of promising natural substance

UNC scientists confirm and clarify key molecular details of nucleotide excision repair

Exposure to heightened air pollution increases risk of Type 2 diabetes in obese Latino children

Advances in prosthetic knee technology

TSRI chemists create new technique for constructing chiral drug molecules

Single Molecule Detection of Proteins in Single Cells

Neutron analysis helps better understand key bacterial enzyme implicated in stomach cancer

Advancing Intracellular Delivery with LumiPore®

How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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