Hematology News and Research

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Hematology, also spelled haematology, is the branch of biology (physiology), pathology, clinical laboratory, internal medicine, and pediatrics that is concerned with the study of blood, the blood-forming organs, and blood diseases. Hematology includes the study of etiology, diagnosis, treatment, prognosis, and prevention of blood diseases.

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

Based on proof-of-concept results from clinical trials at University of North Carolina Lineberger Comprehensive Cancer Center and Baylor College of Medicine, an investigational cellular immunotherapy for Hodgkin lymphoma has received a Regenerative Medicine Advanced Therapy designation from the U.S. Food and Drug Administration.

9 Mar 2020

New sepsis intervention enhances the body's bacteria-capturing neutrophil extracellular traps

Researchers at Children's Hospital of Philadelphia have developed a novel treatment for sepsis - one of the leading causes of hospital death - that enhances the body's bacteria-capturing neutrophil extracellular traps so that they more effectively capture infectious bacteria, resist degradation, and improve sepsis outcomes and survival.

5 Mar 2020

Brain imaging may help predict when liquid biopsy will benefit individual glioblastoma patients

Tracking brain cancer with a blood test instead of a surgical biopsy may greatly improve quality of life for glioblastoma (GBM) patients and provide critical information for their care, but it is not feasible in all cases.

27 Feb 2020

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

Many patients with rare, fast-growing neuroendocrine tumors respond well to a common immunotherapy drug combination, according to the first peer-reviewed publication out of DART, short for Dual Anti-CTLA-4 and Anti-PD-1 Blockade in Rare Tumors, a unique rare cancer clinical trial.

24 Feb 2020

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Like most people, John Gifford wasn't looking forward to a colonoscopy when he arrived on the UCI Medical Center campus in Orange in 2018.

23 Feb 2020

Study exposes the Achilles' heel of deadly ccRCC tumors

An experimental drug already shown to be safe and help some patients with clear cell renal cell carcinoma, a deadly form of kidney cancer, effectively disables its molecular target.

20 Feb 2020

New project aims to gain insights into bone metastasis in breast cancer patients

A new project just launched at Karl Landsteiner University of Health Sciences in Krems aims at gaining insights into the development of bone metastases in breast cancer patients and identifying biomarkers as well as new treatment strategies.

20 Feb 2020

New set of recommendations for managing liver failure in the ICU

For critical care specialists, hepatic failure poses complex challenges unlike those of other critical illnesses.

16 Feb 2020

Research reveals novel way to treat cancers using CAR T cell therapy

Too many patients with cancers like multiple myeloma relapse after treatment. This grim reality motivated researchers at Huntsman Cancer Institute at the University of Utah to try to improve the depth and durability of treatment response in multiple myeloma through a new cancer cell targeting mechanism.

10 Feb 2020

Comparing DNA-repair gene mutations in African American and Caucasian men with prostate cancer

Pathogenic or likely pathogenic alterations in these 14 DNA repair genes were less likely to be detected in African Americans as compared to Caucasians.

3 Feb 2020

Death receptor pathway drives resistance to CAR T cell therapy

Some cancer cells refuse to die, even in the face of powerful cellular immunotherapies like CAR T cell therapy, and new research from the Abramson Cancer Center of the University of Pennsylvania is shedding light on why.

30 Jan 2020

Study may help develop ibrutinib-based combination therapies for blood cancer

Chronic lymphocytic leukemia (CLL) is the most common form of blood cancer (leukemia) in the Western world, affecting approximately 1.2% of all cancer patients.

30 Jan 2020

Researchers develop new strategy to study childhood brain tumors

Researchers are at work to find effective treatments to help young patients with brain tumors. Hundreds of brain organoids have been developed in the laboratories of the University of Trento to understand the genetic mechanisms responsible for these hard to treat diseases.

29 Jan 2020

Study sheds light on mechanisms that underlie a rare genetic condition

A team of researchers at CHU Sainte-Justine and Université de Montréal has shed light on the mechanisms that underlie a rare genetic condition by creating the first cellular model of the disease.

22 Jan 2020

Research paves the way to improved treatment for complex blood disorders

Nearly 1.6 billion people worldwide suffer from anemia, and for the first time new research points to how resistance emerges to the drug dexamethasone used to treat the devastating inherited form of anemia known as Diamond Blackfan anemia.

22 Jan 2020

First randomized clinical trial compares targeted therapies for acute lymphoblastic leukemia

Researchers from St. Jude Children's Research Hospital and the Chinese Children's Cancer Group led the first randomized, Phase III clinical trial comparing targeted therapies for acute lymphoblastic leukemia (ALL) driven by the Philadelphia chromosome.

17 Jan 2020

Beckman Coulter collaborates with SWLP to aid sepsis diagnosis and management in the UK

Beckman Coulter , a global leader in clinical diagnostics, announced today that South West London Pathology (SWLP) has implemented DxH 900 hematology analyzers and the Early Sepsis Indicator across the SWLP network.

From Beckman Coulter Diagnostics 9 Jan 2020

Dog study suggests that AAV in gene therapy could induce cancer

A gene therapy study in dogs has stirred up old fears that by using AAV in gene therapy, it may be increasing cancer chances.

8 Jan 2020

Palmetto GBA now covers Genomic Testing Cooperative’s solid tumor molecular profile

Genomic Testing Cooperative, LCA announced that the Medicare Administrative Contractor Palmetto GBA (MolDx) has established coverage for its solid tumor molecular profile.

7 Jan 2020

Temperature fluctuations could give early indications of graft-versus-host disease

By continuously monitoring the body temperature of mice that had undergone bone-marrow transplants, researchers were able to detect early warning signs of graft-versus-host disease - a dangerous, sometimes deadly response of the transplanted immune system - in a simple, non-invasive way.

6 Jan 2020

Hematology News and Research

Further Reading

Investigational CAR-T therapy for Hodgkin lymphoma receives fast-track designation from FDA

New sepsis intervention enhances the body's bacteria-capturing neutrophil extracellular traps

Brain imaging may help predict when liquid biopsy will benefit individual glioblastoma patients

Immunotherapy drug combination effective for patients with fast-growing neuroendocrine tumors

UCI makes tremendous strides in prevention, early detection and treatment of cancer

Study exposes the Achilles' heel of deadly ccRCC tumors

New project aims to gain insights into bone metastasis in breast cancer patients

New set of recommendations for managing liver failure in the ICU

Research reveals novel way to treat cancers using CAR T cell therapy

Comparing DNA-repair gene mutations in African American and Caucasian men with prostate cancer

Death receptor pathway drives resistance to CAR T cell therapy

Study may help develop ibrutinib-based combination therapies for blood cancer

Researchers develop new strategy to study childhood brain tumors

Study sheds light on mechanisms that underlie a rare genetic condition

Research paves the way to improved treatment for complex blood disorders

First randomized clinical trial compares targeted therapies for acute lymphoblastic leukemia

Beckman Coulter collaborates with SWLP to aid sepsis diagnosis and management in the UK

Dog study suggests that AAV in gene therapy could induce cancer

Palmetto GBA now covers Genomic Testing Cooperative’s solid tumor molecular profile

Temperature fluctuations could give early indications of graft-versus-host disease

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Latest eBooks

Industry Focus eBook - Analytical Chemistry (3rd edition)

Industry Focus eBook - Microbiome (1st edition)

Industry Focus eBook - Cell biology (5th edition)

Advancing degrader and proximity-based drug development

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo