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Fungi used to produce food products have potential probiotic effects on gut inflammation

Many fungus strains have been used and selected by the food industry for their capacities to ferment, produce flavors or produce heterologous molecules.

26 Oct 2023

New nanoparticle-based system developed for comprehensive treatment of rheumatoid arthritis

A team of scientists led by KOO Sagang from the Seoul National University and Center for Nanoparticle Research within the Institue for Basic Science Center (IBS), in collaboration with researchers from Korea Institute of Science and Technology (KIST) and the Seoul National University, developed a new solution for the treatment of rheumatoid arthritis (RA).

26 Oct 2023

Researchers identify mechanism through which dietary omega 3 supplements alleviate liver condition

A study spearheaded by Oregon State University has shown why certain polyunsaturated fatty acids work to combat a dangerous liver condition, opening a new avenue of drug research for a disease that currently has no FDA-approved medications.

25 Oct 2023

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

Certain gut-dwelling fungi flourish in severe cases of COVID-19, amplifying the excessive inflammation that drives this disease while also causing long-lasting changes in the immune system, according to a new study led by investigators at Weill Cornell Medicine and NewYork-Presbyterian.

24 Oct 2023

New "pseudo cell" formulation could revolutionize treatment of vitreoretinal diseases

Researchers from the Institute of Process Engineering (IPE) of the Chinese Academy of Sciences and Beijing Chaoyang Hospital have developed a new "pseudo cell" formulation based on self-healing microcapsule-loading exosomes to treat diverse vitreoretinal diseases.

24 Oct 2023

Study reveals how tuberculosis bacteria form cords to resist antibiotics

The ability of Mycobacterium tuberculosis (MTB), a serious respiratory infection, to form snake-like cords was first noted nearly 80 years ago. In a study published October 20 in the journal Cell, investigators report the biophysical mechanisms by which these cords form and demonstrate how several generations of dividing bacteria hang together to create these structures that enable resistance to antibiotics.

20 Oct 2023

Atovaquone "chemical vaccine" for malaria could be more feasible than thought

Johns Hopkins researchers looking to develop a long-acting, injectable malaria preventive using atovaquone have shown in a new study that resistance may not be the challenge scientists thought it was, particularly when using atovaquone as a malaria preventive.

20 Oct 2023

How ketamine treatment elicits long-lasting anti-depressive effects

Researchers discuss the mechanisms responsible for the sustained antidepressant effects of ketamine by examining ketamine-NMDAR interactions.

20 Oct 2023

Brain natriuretic peptide plays a role in activating atopic dermatitis

Researchers from North Carolina State University have pinpointed a particular peptide's role in activating atopic dermatitis, or eczema. The work could lead to more effective treatments for the condition.

19 Oct 2023

Multidrug-resistant E.coli outcompete harmless strains to take over the gut, study reveals

Different strains of E.coli can outcompete one another to take over the gut, a new study reveals.

17 Oct 2023

Mitochondrial protein CHCHD2 plays important role in glioblastoma progression

Glioblastoma is the most common type of brain tumor that affects adults and, unfortunately, still remains incurable. In a new study, researchers have demonstrated that a specific mitochondrial protein plays an important role in glioblastoma, and can therefore be used as a potential target to reduce tumors.

17 Oct 2023

“Goblet cells” play an important role in the development of allergic conjunctivitis

The first step in the development of the allergic conjunctivitis is the penetration of the allergen through the epithelial layer.

17 Oct 2023

Paxlovid treatment provides protection against COVID-19 for both mother and child

A new mouse model of infection with the COVID-19-causing SARS-CoV-2 virus during pregnancy tracks closely the disease course doctors have observed in SARS-CoV-2-infected pregnant patients, and suggests that treatment with the antiviral Paxlovid provides protection for both mother and child.

16 Oct 2023

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

The study evaluates the efficacy of a new quadrivalent mRNA influenza vaccine, finding it to be highly immunogenic and protective in a mouse model. Compared to traditional vaccines, the mRNA-based option offers advantages like reduced production time and elimination of the risk of growth-promoting mutations.

15 Oct 2023

New radio-theranostics approach shows promise in the fight against pancreatic cancer

Pancreatic ductal adenocarcinoma (PDAC) is one of the deadliest cancers worldwide, with a 5-year survival rate of less than 10%. Many PDAC tumors in early stage go undetected because they are not found using conventional imaging methods, including fluorodeoxyglucose positron emission tomography (PET) scans.

15 Oct 2023

Deep brain stimulation improves memory and promotes neuron growth in Rett mice

A recent study from the lab of Dr. Jianrong Tang, associate professor at Baylor College of Medicine and principal investigator at the Jan and Dan Duncan Neurological Research Institute (Duncan NRI) at Texas Children's Hospital shows that deep brain stimulation (DBS) of a specific brain region results in a significant and sustained improvement of memory in Rett mice.

13 Oct 2023

Mouse Model News and Research

Fungi used to produce food products have potential probiotic effects on gut inflammation

New nanoparticle-based system developed for comprehensive treatment of rheumatoid arthritis

Researchers identify mechanism through which dietary omega 3 supplements alleviate liver condition

Study sheds light on role of gut fungi in severe COVID-19 and long COVID

New "pseudo cell" formulation could revolutionize treatment of vitreoretinal diseases

Study reveals how tuberculosis bacteria form cords to resist antibiotics

Atovaquone "chemical vaccine" for malaria could be more feasible than thought

How ketamine treatment elicits long-lasting anti-depressive effects

Brain natriuretic peptide plays a role in activating atopic dermatitis

Multidrug-resistant E.coli outcompete harmless strains to take over the gut, study reveals

Mitochondrial protein CHCHD2 plays important role in glioblastoma progression

“Goblet cells” play an important role in the development of allergic conjunctivitis

Paxlovid treatment provides protection against COVID-19 for both mother and child

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

New radio-theranostics approach shows promise in the fight against pancreatic cancer

Deep brain stimulation improves memory and promotes neuron growth in Rett mice

Accelerating drug discovery with analytical R&D solutions

Mucin glycosylation plays crucial role in protecting against obesity and intestinal inflammation

Study highlights YB-1 targeting as novel treatment approach for pleural mesothelioma

Stress-induced ribosome dysregulation may underlie depression

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How ELRIG Is Helping Mid-Career Scientists Navigate Leadership, Career Change and Redundancy

The role of UV-Vis in biopharma QC

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