Mouse Model News and Research

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Study suggests iron accumulation plays a central role in senescence and fibrosis

Researchers investigated the association between cellular damage, iron buildup, senescence, and fibrosis.

18 Dec 2023

Seaweed-based hydrogel promises pain-free wound healing

Acting as the main interface between the internal and the external world, the skin is the largest and most important organ of the human body. It is frequently exposed to many types of physical injuries or wounds, including cuts, scrapes, scratches, infections, and ulcers.

15 Dec 2023

UCL researchers develop new gene therapy to cure severe childhood epilepsy

UCL researchers have developed a new gene therapy to cure a devastating form of childhood epilepsy, which a new study shows can significantly reduce seizures in mice.

14 Dec 2023

Researchers identify the culprit responsible for harmful inflammation in certain muscular disorders

Inflammation is an important part of the body's defenses, eliminating threats and repairing damage. When the immune system is overactivated, though, it can turn from friend to foe.

14 Dec 2023

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Mice with human immune cells are a new way of testing anti-cancer drugs targeting the immune system in pre-clinical studies.

14 Dec 2023

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Five DNA vaccine candidates based on different SARS-CoV-2 strains.

12 Dec 2023

Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

Transcranial photobiomodulation (tPBM) treatment affected insulin therapy on microglial function.

12 Dec 2023

Study identifies key factor in lung and eye damage in preemies

Advancements in the care of premature babies are leading to improved survival rates. However, the incidence of neonatal diseases with life-long consequences such as bronchopulmonary dysplasia (BPD) and retinopathy of prematurity (ROP) is increasing.

11 Dec 2023

MIT scientists develop nanoparticles to reduce inflammation in the brain

Some Covid-19 vaccines safely and effectively used lipid nanoparticles (LNPs) to deliver messenger RNA to cells. A new MIT study shows that different nanoparticles could be used for a potential Alzheimer's disease (AD) therapy.

11 Dec 2023

VUB researchers develop a nanobody-based technology to prevent liver inflammation

Mathieu Vinken, a professor in the In Vitro Toxicology and Dermato-cosmetology (IVTD) lab at the Vrije Universiteit Brussel, and doctoral student Raf Van Campenhout have developed a technique based on nanobody technology to prevent liver inflammation.

8 Dec 2023

Study may shed light on new ways to counteract the effects of high blood pressure on cognition

A study supported by the National Institutes of Health suggests that the response of immune system cells inside the protective covering surrounding the brain may contribute to the cognitive decline that can occur in a person with chronic high blood pressure.

5 Dec 2023

Postpartum phagocytosis of pancreatic β-cells by macrophages regulates blood glucose levels

Pancreatic beta cells (β-cells) reside in a cluster of cells in the pancreas known as the islets of Langerhans.

4 Dec 2023

Pancreatic vagus nerve stimulation boosts insulin production in mice

Insulin is a hormone that decreases blood glucose levels. The only cells that produce insulin are pancreatic beta cells (β-cells), and a decrease in these cells is a major cause of diabetes.

4 Dec 2023

LysoPI lipids show promise in boosting insulin secretion in diabetics

While sugar is the most frequently named culprit in the development of type 2 diabetes, a better understanding of the role of fats is also essential.

4 Dec 2023

Gut microbe Lactobacillus found to bolster stress resilience, new study reveals

Study demonstrates that the gut microbe Lactobacillus helps maintain normal levels of the cytokine interferon-gamma (IFNγ), providing protection against stress-induced disruptions in a mouse model. The findings suggest Lactobacillus's crucial role in building resilience to environmental stressors, highlighting its potential in treating mood disorders.

3 Dec 2023

Mouse Model News and Research

Study suggests iron accumulation plays a central role in senescence and fibrosis

Seaweed-based hydrogel promises pain-free wound healing

UCL researchers develop new gene therapy to cure severe childhood epilepsy

Researchers identify the culprit responsible for harmful inflammation in certain muscular disorders

Researchers develop humanized mouse model for macrophage-targeted cancer immunotherapy

Evaluation of immunogenicity-induced DNA vaccines against different SARS-CoV-2 variants

Revolutionizing diabetes care: tPBM therapy proves effective in restoring microglial health

Study identifies key factor in lung and eye damage in preemies

MIT scientists develop nanoparticles to reduce inflammation in the brain

VUB researchers develop a nanobody-based technology to prevent liver inflammation

Study may shed light on new ways to counteract the effects of high blood pressure on cognition

Postpartum phagocytosis of pancreatic β-cells by macrophages regulates blood glucose levels

Pancreatic vagus nerve stimulation boosts insulin production in mice

LysoPI lipids show promise in boosting insulin secretion in diabetics

Gut microbe Lactobacillus found to bolster stress resilience, new study reveals

Scientists unlock secrets of preeclampsia

New insights into evolution of the “little brain”

Researchers discover how rapid tendon regeneration occurs in newts

Link between stress and autoimmunity: New insights into depression from mice to humans

Researchers discover way to reverse brain aging caused by COVID-19

Event guide: 4th Extra-Hepatic Lipid-Based Nanoparticles Delivery Summit eBook

Advancing Neuroscience Research Through Collaboration and Patient-Centered Innovation

The impact of vibration on microscopy

How Omics Technologies Are Transforming Biological Research and Drug Discovery

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