Polymerase Chain Reaction News and Research

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Polymerase chain reaction (PCR) is a revolutionary laboratory technique that enables the replication of a specific DNA sequence. Using PCR, millions of copies of a target DNA can be easily synthesized within a short period of time.

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

In a new study, researchers reported on the non-ACE2 blocking neutralizing antibodies elicited in response to severe coronavirus disease 2019 using deep ribonucleic acid sequencing with >100 million reads per sample and molecular dynamic simulations.

5 Jul 2022

Effectiveness of two and three doses of BNT162b2 against hospital and ED admissions for BA.1 and BA.2 infection

Researchers compared the effectiveness of two and three-dose regimens of COVID-19 vaccine BNT1262b against Omicron BA.1 and BA.2-related hospital and ED admissions.

5 Jul 2022

The varying patterns of acute respiratory infection hospitalizations before and during two pandemic years

Investigators analyzed the varying pattern of respiratory viruses resulting in hospitalizations from 2012-2013 to 2021-2022 in Canada.

5 Jul 2022

Study looks at pneumococcal carriage among over 60's during COVID pandemic

In a recent article posted to the medRxiv* preprint server, researchers in the United States analyzed the pneumococcal carriage in older adults in the Greater New Haven Area, United States (US), during the implementation of coronavirus disease 2019 (COVID-19) mitigation strategies.

4 Jul 2022

Enteric viruses found to transmit through the salivary route

Researchers reported on the productive and persistent infection of salivary glands (SGs) by enteric viruses, with oral cavity titers similar to intestinal titers.

4 Jul 2022

Lower diaphragmatic thickness found among long COVID patients with unspecific fatigue and dyspnea

Researchers defined the sonographic diaphragm phenotype of long coronavirus disease (COVID) patients with unspecific fatigue and dyspnea.

4 Jul 2022

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

Researchers assessed the association between obesity and T cell frequencies specific to the SARS-CoV-2 antigen.

1 Jul 2022

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

Researchers developed a new detection assay for SARS-CoV-2.

1 Jul 2022

BNT162b2 vaccine induces moderate SARS-CoV-2 immunity in children 5 to 11

In a recent study published in the New England Journal of Medicine, researchers evaluated the effectiveness of the BNT162b2 vaccine against the new severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) variant of concern (VOC) Omicron in five to 11-year-old children.

30 Jun 2022

Rapid test can identify which variant has infected a COVID-19 patient in just a few hours

In just a few hours, UT Southwestern scientists can tell which variant has infected a COVID-19 patient – a critical task that can potentially influence treatment decisions but takes days or weeks at most medical centers.

30 Jun 2022

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

Researchers used isothermal amplification with CRISPR-Cas12a to detect SARS-CoV-2.

30 Jun 2022

South African study shows COVID severity of Omicron BA.1, BA.4, BA.5 all similar

A recent article posted to the medRxiv* preprint server analyzed the illness severity of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron BA.4/BA.5 and prior viral waves in the Western Cape, South Africa.

30 Jun 2022

Research examines possibility of monkeypox transmission in domestic settings

In a recent article posted to the medRxiv* preprint server, researchers conducted environmental sampling for an imported monkeypox virus (MPXV) case in the United Kingdom (UK).

30 Jun 2022

Canada handled COVID well by most measures

In a recent study published in the Canadian Medical Association Journal, researchers assessed how Canada performed on all coronavirus disease 2019 (COVID-19)-related metrics compared to the group of 10 (G10) peer countries: France, Germany, Italy, Belgium, the Netherlands, Sweden, Switzerland, Japan, the United Kingdom, and the United States (US).

30 Jun 2022

The distribution and dynamics of microbial populations on surfaces within a clinical microbiology lab during the COVID-19 pandemic

Researchers evaluated the distribution of microbes on surfaces within a microbiology laboratory.

29 Jun 2022

Polymerase Chain Reaction News and Research

Further Reading

Deep RNA sequencing with molecular dynamic simulations can detect neutralizing antibodies elicited by COVID-19 patients

Effectiveness of two and three doses of BNT162b2 against hospital and ED admissions for BA.1 and BA.2 infection

The varying patterns of acute respiratory infection hospitalizations before and during two pandemic years

Study looks at pneumococcal carriage among over 60's during COVID pandemic

Enteric viruses found to transmit through the salivary route

Lower diaphragmatic thickness found among long COVID patients with unspecific fatigue and dyspnea

Study evaluates if adults with obesity and a history of SARS-CoV-2 infection demonstrate poorer T cell immunity

The identification and characterization of a thermophilic Cas13a ortholog highly active at the temperatures required for RT-LAMP

BNT162b2 vaccine induces moderate SARS-CoV-2 immunity in children 5 to 11

Rapid test can identify which variant has infected a COVID-19 patient in just a few hours

A fast, highly sensitive, point-of-care RT-LAMP and CRISPR/Cas12a assay for the detection of SARS-CoV-2

South African study shows COVID severity of Omicron BA.1, BA.4, BA.5 all similar

Research examines possibility of monkeypox transmission in domestic settings

Canada handled COVID well by most measures

The distribution and dynamics of microbial populations on surfaces within a clinical microbiology lab during the COVID-19 pandemic

Acute COVID-19 and vaccination induce cross-reactive antibody responses in breast milk

Genome analysis of alphacoronavirus and betacoronavirus species from South Korean bats

3rd COVID vaccine significantly reduced hospitalizations and deaths during Australia's 1st Omicron wave

Infectious period in healthy, vaccinated adults with SARS-CoV-2 is limited, study finds

Review and case study illustrates the challenges of monkeypox

Sensing a Healthier Future

Achieving and maintaining ISO/IEC 27001 and BS 10012 certifications

Expanding research and clinical options for children with cancer

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