Proteomics News and Research

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The term 'proteome' was first coined in 1994, and refers to all the proteins in a cell, tissue, or organism. Proteomics refers to the study of the proteome. Because proteins are involved in almost all biological activities, the proteome is a rich source of biological information.

Researchers identify Zika virus proteins with potential to affect brain development

In healthy individuals, the Zika virus causes flu-like symptoms. If a pregnant woman becomes infected, the unborn child can suffer from severe brain abnormalities as a result of mechanisms that have not yet been explained.

4 Sep 2018

Researchers discover potential new approach to block growth of HER2 positive breast cancer

Researchers at Mayo Clinic have identified an important new pathway by which HER2 positive breast cancers grow and have discovered that a dietary supplement called cyclocreatine may block the growth of HER2 positive breast cancer.

30 Aug 2018

Research shows proteomics can be used to predict evolution of triple negative breast cancer

The rarest, but also the most aggressive and hard to treat form of breast cancer, is known as triple negative. For this type of cancer, researchers have so far been unable to identify markers that can classify patients by prognosis or probability of responding to different treatments.

29 Aug 2018

Researchers report how Zika proteins hijack host cells

Most people infected with Zika never show symptoms. But the virus sometimes causes severe disability -- from microcephaly in babies to weakness or partial paralysis in adults -- and there is no treatment.

28 Aug 2018

Researchers take major step in eliminating cancer without harming healthy tissue

A major advance towards targeting cancer without harming healthy tissue has been discovered by University of Bristol researchers.

24 Aug 2018

Finding ways to improve cell replacement therapy for Parkinson's disease

Parkinson's disease is a neurodegenerative disease that affects dopamine signaling neurons in patients' brains. Cell-replacement therapy shows some promise as a treatment for Parkinson's. A recent paper in the journal Molecular & Cellular Proteomics reports a technical advance in selecting cells to use in this therapy.

24 Aug 2018

Spanish Flu viruses induce changes in master cellular regulator, shows research

The 1918 "Spanish Flu" was one of the most devastating pandemics in human history, killing 50-100 million people.

22 Aug 2018

Research provides drug developers with much needed insight into serotonin receptor

Serotonin, known as the "happiness" neurotransmitter, is a chemical found in the body responsible for feelings of well-being. But serotonin isn't the only chemical that binds to the 13 serotonin receptors found on the surface of cells. Far from it. Many approved drugs also bind to serotonin receptors.

21 Aug 2018

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes.

17 Aug 2018

Eating white button mushrooms could improve regulation of glucose in the liver

Eating white button mushrooms can create subtle shifts in the microbial community in the gut, which could improve the regulation of glucose in the liver, according to a team of researchers.

16 Aug 2018

Researchers move closer to finding potential soft spot in drug-resistant tuberculosis

Antibiotic-resistant tuberculosis is a public health threat. TB and other bacteria become resistant to antibiotics by evolving genetic changes over time, which they can do quite quickly because bacterial lifecycles are short.

15 Aug 2018

Study provides insight into link between sleep apnea and lipid metabolism

Obstructive sleep apnea is a clinical disorder characterized by repeated partial or complete blockage of the airway during sleep.

15 Aug 2018

Structure of a long-chain lipid that keeps our tears clear revealed

As anyone who has experienced an annoying alternation between dry and watery eyes can confirm, tears alone aren't enough to keep the eye from drying out. A microscopically thin film of oils known as the tear film lipid layer is key to preventing the tear film from evaporating.

9 Aug 2018

Next-generation metabolomics may pave way for creating new antidepressants

Depression is one of the most common diseases that affects at least 4.4% of the world population since 2015. Current antidepressants are limited by their undesirable side effects and slow onset.

7 Aug 2018

New study uses metabolomics to compare lipid profiles of infant formulas and human milk

Metabolomics is the latest omics systems science technology with emerging applications towards psychiatry, personalized medicine, and most recently, precision nutrition research.

3 Aug 2018

CellMax Life receives six U.S. patents for early cancer detection blood test

CellMax Life, enabling early cancer detection and management with affordable, non-invasive blood tests, announced today that six U.S. patents have been granted for its biomimetic platform CMx, which detects circulating tumor cells.

26 Jul 2018

Researchers explore why heart failure and kidney disease correlate

People with chronic kidney disease are at unusually high risk of also developing cardiovascular disease; in fact, a patient with non-dialysis kidney disease is more likely to die of heart failure than to develop end-stage kidney failure.

24 Jul 2018

Sleep disturbances associated with higher dementia risk

Researchers at Karolinska Institutet in Sweden report that sleep disturbances in midlife or in late life are associated with a higher risk for developing dementia in old age. The results are published in Alzheimer's & Dementia: The Journal of the Alzheimer's Association.

20 Jul 2018

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

The brains of people with Alzheimer's disease contain many protein aggregates outside of cells, known as plaques. These are mainly made of the peptide amyloid-beta, which is released from the plasma membrane when the protease BACE1 cleaves its membrane-anchored precursor protein.

19 Jul 2018

Study calls for new gold standard in research to treat non-alcoholic steatohepatitis

A new study by scientists from the Vrije Universiteit Brussel calls for a new gold standard in research to treat non-alcoholic steatohepatitis, an obesity-linked chronic liver disease impacting millions of people of all ages worldwide, which can progress to liver cancer if untreated, creating a massive strain on an already overburdened healthcare system.

18 Jul 2018

Proteomics News and Research

Further Reading

Researchers identify Zika virus proteins with potential to affect brain development

Researchers discover potential new approach to block growth of HER2 positive breast cancer

Research shows proteomics can be used to predict evolution of triple negative breast cancer

Researchers report how Zika proteins hijack host cells

Researchers take major step in eliminating cancer without harming healthy tissue

Finding ways to improve cell replacement therapy for Parkinson's disease

Spanish Flu viruses induce changes in master cellular regulator, shows research

Research provides drug developers with much needed insight into serotonin receptor

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Eating white button mushrooms could improve regulation of glucose in the liver

Researchers move closer to finding potential soft spot in drug-resistant tuberculosis

Study provides insight into link between sleep apnea and lipid metabolism

Structure of a long-chain lipid that keeps our tears clear revealed

Next-generation metabolomics may pave way for creating new antidepressants

New study uses metabolomics to compare lipid profiles of infant formulas and human milk

CellMax Life receives six U.S. patents for early cancer detection blood test

Researchers explore why heart failure and kidney disease correlate

Sleep disturbances associated with higher dementia risk

New proteomics studies help gain more insights into Alzheimer's, cancer and listeriosis

Study calls for new gold standard in research to treat non-alcoholic steatohepatitis

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