Nephrology News and Research

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Nephrology is a branch of internal medicine and pediatrics dealing with the study of the function and diseases of the kidney.

Chronic kidney disease is rising rapidly worldwide

In the United Kingdom, the annual incidence of end stage renal disease is around 100 per 1,000,000 population. This figure has doubled over the past decade and is expected to continue to rise by 5-8% annually

13 Mar 2006

Transplanting a pair of kidneys with limited function into one patient may offer one solution to short supply of donated kidneys

Transplanting a pair of kidneys with limited function into one patient can be just as successful as the standard procedure in which a patient receives a single kidney, according to new research at Wake Forest University Baptist Medical Center.

13 Mar 2006

Positive effects of tight blood glucose control can be seen more than a decade later in diabetics

People with diabetes who keep their blood sugar in check today will probably have a far lower chance of developing foot pain or other nerve damage tomorrow, according to new research results from a national study.

9 Mar 2006

Therapy for metastatic renal cell carcinoma remains inadequate

The recent FDA approvals of the tyrosine kinase inhibitors sorafenib and sunitinib based on their activity in metastatic renal cell carcinoma have excited the medical oncology community

9 Mar 2006

Nebivolol may restore damaged cardiovascular functions in African Americans

Tadeusz Malinski, Marvin & Ann Dilley White Professor of Chemistry and Biochemistry, found that the drug, currently under review by the U.S. Food and Drug Administration, acts on the level of oxidants lining the cardiovascular system and can restore levels of nitric oxide and reduce oxidative stress.

9 Mar 2006

Thalidomide improves remission in myeloma

Myeloma is one of the least curable cancers and involves plasma cells, the white blood cells that produce antibodies.

9 Mar 2006

New hepatitis drug much more effective

Chronic infection with the hepatitis B virus (HBV) is responsible for an enormous burden of disease throughout the world, including up to half of all cases of cirrhosis, end-stage liver disease, and hepatocellular carcinoma, a cancer of the liver.

9 Mar 2006

Test for LDH enzyme may help determine risk factors in sickle cell disease

Researchers have found that a simple test for an enzyme called LDH may have significant importance for determining major risk factors in adults with sickle cell disease.

9 Mar 2006

Primary vesicoureteral reflux detected in neonates with a history of fetal renal pelvis dilatation

Fetal renal pelvis dilatation is a common abnormality, observed in 4.5% of pregnancies but surrounded by controversy regarding its significance. Working up renal pelvis dilation has become a standard of care regardless of the presence or absence of symptoms with vesicoureteral reflux (VUR) being one of the primary concerns.

8 Mar 2006

Is partial nephrectomy oncologically safe for tumors greater than 4cm?

Traditionally, nephron sparing surgery in the presence of a normal contralateral kidney is primarily advocated for tumors <= 4cm.

7 Mar 2006

Pre-eclampsia kidney disease link

Pre-eclampsia is a complication in pregnancy occurring in approximately eight percent of all pregnancies. It is characterised by elevated blood pressure and protein in the urine. It generally develops after 20 weeks of pregnancy.

7 Mar 2006

Study looks at how two forms of vitamin E affect the health of animal cells

One of the most powerful antioxidants is truly a double-edged sword, say researchers at Ohio State University who studied how two forms of vitamin E act once they are inside animal cells.

7 Mar 2006

Cutting out the sodas equals weight loss for teens

Researchers from the Children's Hospital Boston say that the surge in children's consumption of sugar-sweetened drinks such as sodas, sports drinks, "juice drinks," iced teas, lemonades and punches matches the rise in childhood obesity.

7 Mar 2006

Plastic surgeons describe possibility of full facial tissue transplantation from one human body to another

Even after news of the first partial facial transplantation performed in France spread around the world, plastic surgeons have continued to research how to make the first full facial transplantation a reality.

7 Mar 2006

Pfizer acquires worldwide rights to Exubera

Pfizer has announced that it has acquired the sanofi-aventis worldwide rights to Exubera (inhaled human insulin). Pfizer received approval last month to market Exubera in the United States and the European Union for the treatment of adults with type 1 and type 2 diabetes.

1 Mar 2006