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Effects of COVID-19 treatment best with combination therapy

There is a steadily growing arsenal of drugs for COVID-19. Researchers from Charité – Universitätsmedizin Berlin, the Max Delbrück Center for Molecular Medicine (MDC) and Freie Universität (FU) Berlin have studied the mechanisms of action of antiviral and anti-inflammatory drugs.

15 Apr 2022

Acute stroke associated with considerable loss in life expectancy

Almost two-thirds of acute stroke patients fail to survive more than a decade and have high risk of recurrence, prompting researchers to call for better patient care.

15 Apr 2022

New study paves the way for first drug treatment for sleep apnea

A new University of Gothenburg study has paved the way for the first drug treatment for sleep apnea. Compared to before receiving the treatment, breathing pauses decreased with on average more than 20 per hour for patients given the drug.

15 Apr 2022

New short-course treatment effective against HIV-associated cryptococcal meningitis

A new short-course treatment is effective against HIV-associated cryptococcal meningitis with fewer serious side effects, and has the potential to reduce the length and cost of hospital admissions, a study shows.

15 Apr 2022

Exploring strategies for successful delivery of messenger RNA therapeutics

Researchers reviewed the material properties and administration routes that could successfully deliver a messenger ribonucleic acid therapeutic agent to its targeted site.

14 Apr 2022

Single-dose vaccine delivers protection against cervical cancer-causing HPV comparable to 2 or 3-dose regimes

A recent report suggested that a single dose of the human papillomavirus (HPV) vaccination confers equivalent immunity to a two-dose schedule against cervical cancers caused by HPV.

14 Apr 2022

Novel transdermal vaccine delivery for COVID-19 and cancer

Researchers assess the efficacy of a fluorocarbon modified chitosan system for the development of SARS-CoV-2 vaccines and tumor immunotherapy.

13 Apr 2022

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

Researchers at Mayo Clinic's Center for Individualized Medicine have devised an immunotherapy technique that combines chimeric antigen receptor-T cell therapy, or CAR-T cell therapy, with a cancer-killing virus to more effectively target and treat solid cancer tumors.

13 Apr 2022

Researchers find novel inhibitors that may suppress oncogenesis of metastatic prostate cancer

Researchers have found that treating prostate cancer cells with novel cyclin-dependent kinase 19 (CDK19) and homologous cyclin-dependent kinase 8 (CDK8) inhibitors reduces their potential to migrate into and invade surrounding structures.

13 Apr 2022

Study: About half of young adults reported mental health symptoms during the pandemic

About half of young adults had mental health symptoms during the pandemic and more than a third of those were unable to access mental health therapy, a new UC San Francisco study found.

13 Apr 2022

Scientific statement from the American Heart Association on COVID-19 and cardiovascular complications in children and adolescents

A recent scientific statement published in Circulation reviewed the current knowledge on COVID-19.

13 Apr 2022

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

Acute lymphoblastic leukemia (ALL) cells from patients whose cancers did not respond to CD19-targeted CAR T therapy had gene regulation signatures that could potentially facilitate treatment resistance, according to results presented at the AACR Annual Meeting 2022, held April 8-13.

13 Apr 2022

New drug shows promise in treating a movement disorder associated with Huntington's disease

A new drug has proven beneficial in treating a movement disorder commonly associated with Huntington's disease, according to a recent international study led by UTHealth Houston researcher Erin Furr Stimming, MD, who served as principal investigator on behalf of the KINECT-HD Huntington Study Group.

13 Apr 2022

Bioprinting for bone repair enhanced with two growth factor encoding genes

Given enough time and energy, the body will heal, but when doctors or engineers intervene, the processes do not always proceed as planned because chemicals that control and facilitate the healing process are missing.

13 Apr 2022

Two in five adults with ADHD found to be in excellent mental health

A new nationally representative study published online in the International Journal of Applied Positive Psychology found two in five adults (42%) with attention deficit hyperactivity disorder (ADHD) were in excellent mental health.

12 Apr 2022

New bioinformatics platform predicts optimal treatment combinations for cancer patients

Researchers at The University of Texas MD Anderson Cancer Center have developed a new bioinformatics platform that predicts optimal treatment combinations for a given group of patients based on co-occurring tumor alterations.

12 Apr 2022

$2 million funding to support Friendship Bench program for helping people with mental health issues

Many more people with depression and other mental health issues will be able to get help from the Friendship Bench programme thanks to a $2 million unrestricted funding from the philanthropist MacKenzie Scott.

12 Apr 2022

Third dose of messenger RNA vaccines found to increase serological immunity in hematological malignancy patients

In a new study, researchers quantified the serological responses following the third dose of mRNA-based COVID-19 vaccines in patients with hematological malignancies.

12 Apr 2022

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Heart complications are uncommon, yet treatable for children and young adults after COVID-19 disease or SARS-CoV-2 infection, according to a new scientific statement from the American Heart Association that details what has been learned about how to treat, manage and even prevent cardiovascular complications from the SARS-CoV-2 virus in youth.

12 Apr 2022

Experimental tool can precisely pick out interactions between immune cell and target antigen

The human body has millions of unique B and T cells that roam the body, looking for microbial invaders. These immune cells' ability to recognize harmful microbes is critical to successfully fighting off infection.

12 Apr 2022

Therapy News and Research

Effects of COVID-19 treatment best with combination therapy

Acute stroke associated with considerable loss in life expectancy

New study paves the way for first drug treatment for sleep apnea

New short-course treatment effective against HIV-associated cryptococcal meningitis

Exploring strategies for successful delivery of messenger RNA therapeutics

Single-dose vaccine delivers protection against cervical cancer-causing HPV comparable to 2 or 3-dose regimes

Novel transdermal vaccine delivery for COVID-19 and cancer

Mayo Clinic researchers devise a combination approach to more effectively target solid tumors

Researchers find novel inhibitors that may suppress oncogenesis of metastatic prostate cancer

Study: About half of young adults reported mental health symptoms during the pandemic

Scientific statement from the American Heart Association on COVID-19 and cardiovascular complications in children and adolescents

Researchers identify certain gene regulation signatures in CAR T-resistant leukemia patients

New drug shows promise in treating a movement disorder associated with Huntington's disease

Bioprinting for bone repair enhanced with two growth factor encoding genes

Two in five adults with ADHD found to be in excellent mental health

New bioinformatics platform predicts optimal treatment combinations for cancer patients

$2 million funding to support Friendship Bench program for helping people with mental health issues

Third dose of messenger RNA vaccines found to increase serological immunity in hematological malignancy patients

Heart complications uncommon for children and young adults after SARS-CoV-2 infection

Experimental tool can precisely pick out interactions between immune cell and target antigen

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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