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OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

The first results from the POISE biopsy sub-study have today confirmed that long-term treatment with obeticholic acid leads to the reversal or stabilization of fibrosis/cirrhosis in patients with primary biliary cholangitis who have had an incomplete response to ursodeoxycholic acid.

13 Apr 2018

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

The final results of the palliative cohort of the SORAMIC study in patients with unresectable, locally advanced primary liver cancer have confirmed no clinical advantage to adding selective internal radiation therapy to standard sorafenib treatment compared with using sorafenib alone.

13 Apr 2018

Study reveals prevalence of substance use and suicide among U.S. adolescents

Examining more than 20 years of national data for U.S. adolescents, a research team led by Andrew Subica at the University of California, Riverside reports that adolescents have high prevalence of alcohol, cigarette, and marijuana use, and concerning rates of suicide-related thoughts and behaviors.

13 Apr 2018

Denial of suicide attempt by self-inflicted gunshot wound survivors may lead to treatment barriers

Researchers have found that more than one-third of patients who denied that their self-inflicted gunshot wound resulted from a suicide attempt most likely had indeed tried to kill themselves, and commonly were sent home from the hospital without further mental health treatment.

13 Apr 2018

UW developmental psychologist wins 2018 Alan T. Waterman Award

The National Science Foundation has bestowed the 2018 Alan T. Waterman Award, the nation's highest honor for early career scientists and engineers, on University of Washington (UW) social and developmental psychologist Kristina R. Olson.

13 Apr 2018

Researchers find possible therapeutic strategy to block self-eating in pancreatic cancers

To get the extra energy they need to fuel their uncontrolled growth, cancer cells break down some of their own parts for fuel - a process known as autophagy, or "self-eating."

13 Apr 2018

Omega-3 supplements found to be ineffective in alleviating dry eye symptoms

More than 16 million Americans suffer from dry eye, an often chronic condition that causes burning, itching, or stinging sensations in the eye, as well as impaired vision.

13 Apr 2018

'Night owls' have higher risk of early death than 'larks'

"Night owls" - people who like to stay up late and have trouble dragging themselves out of bed in the morning - have a higher risk of dying sooner than "larks," people who have a natural preference for going to bed early and rise with the sun, according to a new study from Northwestern Medicine and the University of Surrey in the United Kingdom.

13 Apr 2018

Diabetes screening could miss more than half of high-risk patients

Screening patients for diabetes based solely on their age and weight – a recommendation from a leading medical expert group – could miss more than half of high-risk patients, according to a new Northwestern Medicine study of a nationwide sample.

13 Apr 2018

Brief exposure to pollution-causing particles triggers lung infections in children

Even the briefest increase in airborne fine particulate matter PM2.5, pollution-causing particles that are about 3% of the diameter of human hair, is associated with the development of acute lower respiratory infection in young children, according to newly published research.

13 Apr 2018

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

Scientists used an experimental targeted molecular therapy to block a matrix-forming protein in heart cells damaged by heart attack, reducing levels of scarred muscle tissue and saving mouse models from heart failure.

13 Apr 2018

Protein linked with Alzheimer's disease affects different brain cells differently

Amyloid beta, a protein linked with Alzheimer's disease, has different properties in different cell types in the brains of fruit flies.

13 Apr 2018

Intranasal spray shows promise for peanut allergy suppression

A vaccine delivered in the form of an ultrafine nasal spray has been shown to protect against allergy symptoms peanut sensitive mice.

13 Apr 2018

Glucose metabolism is key to neural network development, finds study

A new study has found that glucose metabolism is critical for the development of neural networks in the brain.

13 Apr 2018

Study: One-third of bacterial infections in patients with cirrhosis induced by MDR bacteria

A worldwide study initiated to investigate the epidemiology and outcomes of bacterial infections in hospitalized patients with liver cirrhosis has reported a prevalence of multi-drug-resistant bacteria of 34% and significant regional differences in the risk of developing a multi-drug-resistant infection.

13 Apr 2018

Biologists discover surprising, additional function for soluble form of SNARE protein

In 2013, the Nobel Prize in Physiology or Medicine was awarded to three scientists for their contributions to uncovering the mechanisms governing vesicle transport in cells. Their explanations provided both a conceptual and a mechanistic understanding of basic processes at the most fundamental level.

13 Apr 2018

PrEP campaign aims to block HIV infection and save lives in D.C.

A big part of Washington, D.C.’s plan to get its HIV rate down is to get more uninfected people on PrEP, a two-medicine combination pill that’s sold under the brand name Truvada.

13 Apr 2018

Medical device coated with new bacteria resistant materials approved for use by hospitals

A medical device coated with new bacteria resistant materials, discovered by a team at the University of Nottingham, has been approved for use by hospitals in the UK and Europe.

13 Apr 2018

Scientists from Cure First and SEngine Precision Medicine discover common link in 28% of all cancers

Seattle scientists from Cure First, a non-profit research organization, and SEngine Precision Medicine, a biotech developing targeted, more effective, and less toxic cancer therapeutics, co-authored one of 27 high-profile papers published today by Cell Press.

13 Apr 2018

Deep learning enhances smartphone microscopes into laboratory-grade equipments

Researchers at the UCLA Samueli School of Engineering have demonstrated that deep learning, a powerful form of artificial intelligence, can discern and enhance microscopic details in photos taken by smartphones. The technique improves the resolution and color details of smartphone images so much that they approach the quality of images from laboratory-grade microscopes.

13 Apr 2018

Research News and Research

OCA treatment stabilizes or reverses fibrosis/cirrhosis in patients with primary biliary cholangitis

Study confirms no survival benefit of adding SIRT to standard treatment for liver cancer

Study reveals prevalence of substance use and suicide among U.S. adolescents

Denial of suicide attempt by self-inflicted gunshot wound survivors may lead to treatment barriers

UW developmental psychologist wins 2018 Alan T. Waterman Award

Researchers find possible therapeutic strategy to block self-eating in pancreatic cancers

Omega-3 supplements found to be ineffective in alleviating dry eye symptoms

'Night owls' have higher risk of early death than 'larks'

Diabetes screening could miss more than half of high-risk patients

Brief exposure to pollution-causing particles triggers lung infections in children

Experimental molecular therapy to block matrix-forming protein may prevent heart failure

Protein linked with Alzheimer's disease affects different brain cells differently

Intranasal spray shows promise for peanut allergy suppression

Glucose metabolism is key to neural network development, finds study

Study: One-third of bacterial infections in patients with cirrhosis induced by MDR bacteria

Biologists discover surprising, additional function for soluble form of SNARE protein

PrEP campaign aims to block HIV infection and save lives in D.C.

Medical device coated with new bacteria resistant materials approved for use by hospitals

Scientists from Cure First and SEngine Precision Medicine discover common link in 28% of all cancers

Deep learning enhances smartphone microscopes into laboratory-grade equipments

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