B Cell News and Research

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Role of phosphatidylinositol 3 kinase pathway in corneal damage due to blue light exposure

Researchers observe corneal damage by blue light exposure is due to PI3K/AKT pathway inhibition.

1 Mar 2023

Gut bacteria influence the liver's regenerative ability

When parts of the liver are removed, the body can replace the missing tissue. A team of researchers at the Technical University of Munich has now discovered that the success of this process depends to a large extent on gut bacteria.

1 Mar 2023

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

The study findings demonstrate the power of spatial single-cell transcriptomics in studying COVID-19 lung pathology and other health and disease conditions.

1 Mar 2023

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Omicron BTIs induce durable neutralizing immune responses by recalling cross-reactive and vaccine-induced memory B lymphocytes.

1 Mar 2023

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

Researchers investigate the role of neurotrophic factors on the cognitive performance of Alzheimer’s disease patients carrying the apolipoprotein E 4 gene.

1 Mar 2023

New cell-based assay shown to rapidly profile drug resistance to three widely used SARS-CoV-2 main protease inhibiting drugs

In a recent study posted to the bioRxiv* pre-print server, researchers tested three next-generation severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) main protease (Mpro) inhibitors, namely, nirmatrelvir, ensitrelvir, and FB2001, using a novel cell-based assay.

1 Mar 2023

Using vitamin B5 supplementation to boost red blood cell production in people with myelodysplastic syndromes

Scientists from Barts Cancer Institute at Queen Mary University of London and the Francis Crick Institute, have uncovered why patients with a rare type of blood cancer suffer from ineffective red blood cell production, and how vitamin B5 could be combined with existing drugs to improve outcomes.

1 Mar 2023

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

In a recent review published in Biomedicines, researchers explored extracellular vesicles (EVs), cell-penetrating peptides (CPPs), and micro ribonucleic acids (miRNAs) as therapies for neurodegenerative diseases such as Alzheimer’s disease (AD) and Parkinson’s disease (PD).

1 Mar 2023

What is the role of B cells in breast cancer pathology?

In a recent study published in Cancers, researchers comprehensively summarized all available information about B cells in the context of breast cancer.

1 Mar 2023

Landmark discovery provides a new perspective on tissue oxygenation

Cardiovascular medicine, hematology and pulmonary medicine may soon have the first-ever therapies to correct poor tissue oxygenation, a key driver of disease in millions, including peripheral artery disease, sickle cell disease, heart failure, stroke, emphysema and many others.

1 Mar 2023

Newly discovered mechanism likely contributes to the severity of P. aeruginosa infections

Bacteria of the species Pseudomonas aeruginosa are antibiotic-resistant hospital germs that can enter blood, lungs and other tissues through wounds and cause life-threatening infections.

1 Mar 2023

Promising alternative strategy for islet transplantation in people with type 1 diabetes

In people with type 1 diabetes, the body's immune system attacks and destroys insulin-producing β cells that control blood glucose levels and are part of a group of cells in the pancreas called pancreatic islets.

1 Mar 2023

Key 'traffic light' mechanism controlling genetic activity within cells revealed

A major new study in the journal Nature reveals a 'traffic light' mechanism controlling genetic activity within cells – a system which could potentially be targeted by cancer drugs already in development.

1 Mar 2023

Clinical study reveals new use for high blood pressure drug in pediatric patients

A clinical study conducted by Indiana University School of Medicine researchers revealed that oral verapamil, a readily available and commonly used drug to treat high blood pressure and heart conditions, can also improve the pancreas' insulin secretion in children with newly-diagnosed type 1 diabetes (T1D).

1 Mar 2023

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

A new study led by researchers at Harvard Medical School details the step-by-step cascade that allows bacteria to break through the brain's protective layers - the meninges - and cause brain infection, or meningitis, a highly fatal disease.

1 Mar 2023

Antiverse raises funding and demonstrates therapeutic antibody identification with AI-driven drug discovery platform

Antiverse Ltd (Antiverse), a biotechnology company developing a computational antibody drug discovery platform, today announced the successful identification of functional antibody clusters targeting two G-protein-coupled receptors (GPCRs), both displaying versatile binding profiles and nanomolar affinity.

From Antiverse 1 Mar 2023

New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Understanding how the knee joint environment affects cartilage cells is crucial for joint health. Knowledge of cell-driven cartilage degeneration mechanisms can support the development of effective pharmaceutical interventions for osteoarthritis.

1 Mar 2023

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Chemotherapy affects the ability of a patient's immune system to attack pancreatic tumors, a new study shows.

1 Mar 2023

Omega-3 fatty acids may be protective against contracting or suffering adverse outcomes of COVID-19

A study just published in the American Journal of Clinical Nutrition (AJCN) explored the role of omega-3 fatty acids, especially EPA and DHA, and whether they might be protective against contracting and/or suffering adverse outcomes of COVID-19 infection.

1 Mar 2023

Product development and drug delivery at Seda

In this interview, NewsMedical speaks with Shanoo about her career progression and role in Seda Pharmaceutical regarding product development and drug delivery. She also outlines some of the services that Seda offers.

From Seda Pharmaceutical Development Services 1 Mar 2023

B Cell News and Research

Role of phosphatidylinositol 3 kinase pathway in corneal damage due to blue light exposure

Gut bacteria influence the liver's regenerative ability

Researchers use spatial single-cell transcriptome technique to examine immune signatures of SARS-CoV-2-infected lungs

SARS-CoV-2 BA.1 and BA.2 breakthrough infections likely protect against BA.4 infection

Research investigates roles of neurotrophic factors on cognition in Alzheimer's patients carrying APOE ε4

New cell-based assay shown to rapidly profile drug resistance to three widely used SARS-CoV-2 main protease inhibiting drugs

Using vitamin B5 supplementation to boost red blood cell production in people with myelodysplastic syndromes

Exploring the neuroprotective potential of cell-penetrating peptides, extracellular vesicles, and micro ribonucleic acids

What is the role of B cells in breast cancer pathology?

Landmark discovery provides a new perspective on tissue oxygenation

Newly discovered mechanism likely contributes to the severity of P. aeruginosa infections

Promising alternative strategy for islet transplantation in people with type 1 diabetes

Key 'traffic light' mechanism controlling genetic activity within cells revealed

Clinical study reveals new use for high blood pressure drug in pediatric patients

Bacteria exploit nerve cells in the meninges to facilitate brain invasion

Antiverse raises funding and demonstrates therapeutic antibody identification with AI-driven drug discovery platform

New numerical model reveals degeneration mechanisms in mechanically loaded and inflamed cartilage

Chemotherapy affects the cellular landscape of tumor microenvironment in pancreatic cancer

Omega-3 fatty acids may be protective against contracting or suffering adverse outcomes of COVID-19

Product development and drug delivery at Seda

Industry Focus eBook - Cell & Gene Therapy (1st Edition) eBook

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

Advancing Intracellular Delivery with LumiPore®

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