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MGH investigators find important regulators of urinary concentration in the kidney

Proper function of the kidney is critical for concentrating urine, regulating blood pressure, and for the tight control of electrolyte levels in the blood.

25 Apr 2022

Study reports increased numbers of SARS-CoV-2-reactive T cells in individuals who were HCoV-reactive

T cell responses were measured to three SARS-CoV-2-associated antigens, as well as the endemic coronaviruses HCoV-OC43 and HCoV-NL63.

25 Apr 2022

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

As part of World Malaria Day 2022, we interview Karine Le Roch PH.D., about her latest research into how novel antimalarial therapeutic strategies could be on the horizon, after identifying two proteins that are critical to the survival of the malaria parasite, Plasmodium falciparum.

25 Apr 2022

Role of complement factor H-related protein 5 in venous thromboembolism and COVID-19

A new study discussed the role of complement factor H-related protein 5 (CFHR5) in venous thromboembolism (VTE) patients and hospitalized COVID-19 patients.

25 Apr 2022

The challenges of Omicron

A new review published in sums up the position of Omicron as a potential threat to human health, especially in the context of controlling this pandemic.

25 Apr 2022

Species differences in somatic mutations shed light on aging

A recent study published in the journal Nature aimed to elucidate, through a comparative analysis, the diversity in mutagenesis across different species, and the long-established hypothesis regarding evolution in the rates of somatic mutation, as well as their role in cancer and aging.

25 Apr 2022

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

In a recent study posted to the bioRxiv* preprint server, the researchers investigated the impact of Bacillus Calmette-Guérin (BCG) vaccine-induced antibodies against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike (S) glycoprotein.

25 Apr 2022

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

A recent review paper, published in the MDPI’s specialized journal COVID, highlights key features of the Omicron variant of the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) – and examines the potential and roadblocks in using renewable marine resources in the fight against the coronavirus disease 2019 (COVID-19).

24 Apr 2022

Detection of prior SARS-CoV-2 infection by T-cell receptor sequencing

A new study describes a novel COVID-19 detection technique based on T-cell receptor sequencing.

24 Apr 2022

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

A new study discusses the potential of certain plant compounds to block SARS-CoV-2 replication within host cells.

24 Apr 2022

Study highlights a rapidly increasing patient population with long COVID and lack of treatments

A new UK study of more than 2,000 patients after hospitalization with COVID-19 presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID 2022, Lisbon 23-26), and published in The Lancet Respiratory Medicine shows that, one year after having COVID-19, only around one in four patients feel fully well again.

24 Apr 2022

Research identifies the third day of hospitalization as a tipping point in progression of COVID-19 pneumonia

New research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases in Lisbon, Portugal, (23-26 April), has identified the third day of hospitalization as a tipping point in the progression of disease among symptomatic patients admitted for COVID-19 pneumonia.

23 Apr 2022

Researchers identify cytokines that can help predict negative outcomes in COVID-19 patients

New research being presented at this year's European Congress of Clinical Microbiology & Infectious Diseases (ECCMID) in Lisbon, Portugal (23-26 April) has identified a panel of cytokines that can help predict which COVID-19 patients are at risk of serious illness and death.

23 Apr 2022

New tool delivers and electrically stimulates stem cells to promote stroke recovery

Study suggests SARS-CoV-2 is undergoing evolutionary changes at the functional RNA level in addition to the amino acid level

Researchers demonstrated SARS-CoV-2 evolution at the transcriptional level.

22 Apr 2022

Antibody escape in SARS-CoV-2 Omicron spike protein

Researchers examined antibody escape and cross-domain stabilization in the SARS-CoV-2 Omicron spike protein.

22 Apr 2022

Study demonstrates that a low-dose, bivalent, unmodified mRNA vaccine against SARS-CoV-2 is highly efficacious

Researchers compared the efficiency of monovalent and bivalent mRNA vaccines against SARS-CoV-2.

22 Apr 2022

Protein C News and Research

MGH investigators find important regulators of urinary concentration in the kidney

Study reports increased numbers of SARS-CoV-2-reactive T cells in individuals who were HCoV-reactive

World Malaria Day 2022: How the knockdown of P. falciparum RAP01 and RAP21 proteins could lead to novel antimalarial therapeutics

Role of complement factor H-related protein 5 in venous thromboembolism and COVID-19

The challenges of Omicron

Species differences in somatic mutations shed light on aging

Study suggests BCG vaccination might confer immunity to SARS-CoV-2

Marine resources could be promising drug candidates against SARS-CoV-2 Omicron

Detection of prior SARS-CoV-2 infection by T-cell receptor sequencing

Quercetin and other plant flavonols show anti-SARS-CoV-2 activity

Study highlights a rapidly increasing patient population with long COVID and lack of treatments

Research identifies the third day of hospitalization as a tipping point in progression of COVID-19 pneumonia

Researchers identify cytokines that can help predict negative outcomes in COVID-19 patients

New tool delivers and electrically stimulates stem cells to promote stroke recovery

Less PSA testing minimizes overdiagnosis but may lead to increase in metastatic prostate cancer cases

The diversity of transcriptional targets between four different coronavirus nsp1 proteins

Interleukin-6 levels predict early withdrawal of COVID-19 patients from mechanical ventilation

Study suggests SARS-CoV-2 is undergoing evolutionary changes at the functional RNA level in addition to the amino acid level

Antibody escape in SARS-CoV-2 Omicron spike protein

Study demonstrates that a low-dose, bivalent, unmodified mRNA vaccine against SARS-CoV-2 is highly efficacious

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

Expanding access to NMR with the Fourier 80 Duo

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