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Experimental gene therapy may improve health outcomes for patients with some forms of blood disorders

New research adds to a growing body of evidence that gene therapy, an experimental technique that involves correcting or replacing a person's mutated or malfunctioning genes, may improve health outcomes for patients with inherited bleeding and immune disorders as well as some forms of blood cancer.

7 Dec 2015

EKF biomarker identifies likely development of Diabetic Nephropathy

EKF, announces new data presented in support of soluble Tumour Necrosis Factor Receptor 1 as a biomarker to predict progression of Diabetic Nephropathy.

From EKF Diagnostics 2 Dec 2015

Bacteriophage therapy: an alternative to antibiotics? An interview Professor Clokie

A phage is a virus that infects a bacterium. People often get very confused about what the difference is between a virus and a bacterium. A virus, like a bacterium, is also a microorganism, but unlike bacteria, it needs to have a host to be able to replicate and propagate.

2 Dec 2015

Synthetic Biologics announces positive results from first SYN-004 Phase 2a study for prevention of CDI, AAD

Synthetic Biologics, Inc.), a clinical stage company focused on developing therapeutics to protect the gut microbiome while targeting pathogen specific diseases, announced positive topline results from the first Phase 2a study of SYN-004, the Company's candidate designed to protect the gut microbiome from the unintended effects of certain commonly used intravenous (IV) beta-lactam antibiotics for the prevention C. difficile infection (CDI) and antibiotic-associated diarrhea (AAD).

1 Dec 2015

Taking estriol along with conventional medications helps RRMS patients avoid relapses

Taking the pregnancy hormone estriol along with their conventional medications helped patients with relapsing-remitting multiple sclerosis (RRMS) avoid relapses, according to results of a Phase II randomized, placebo-controlled study led by UCLA researchers.

1 Dec 2015

STSI launches home-based clinical trial that uses wearable sensors to identify people with AFib

Researchers at the Scripps Translational Science Institute have launched a home-based clinical trial that uses wearable sensor technology to identify people with asymptomatic atrial fibrillation (AFib).

1 Dec 2015

Combination of antiviral medications can eradicate HCV infection in patients with advanced liver disease

A large multi-center clinical trial has found that a combination of antiviral medications can eradicate hepatitis C infection in more than 90 percent of patients with advanced liver disease. Known as the ASTRAL-4 trial, the study was co-led by investigators at Beth Israel Deaconess Medical Center and Intermountain Medical Center and published online Nov. 17 in The New England Journal of Medicine.

1 Dec 2015

UVA opens clinical trial to examine non-surgical treatment for lower urinary tract symptoms

University of Virginia Health System researchers have opened a national clinical trial examining a non-surgical treatment for lower urinary tract symptoms caused by an enlarged prostate.

30 Nov 2015

Could statins treat muscular dystrophy? An interview with Dr. Nick Whitehead and Dr Stan Froehner

In addition to their well established cholesterol lowering benefits, statins also have potent anti-inflammatory, anti-fibrotic and antioxidant effects, which continue to be identified in a wide range of diseases.

30 Nov 2015

Researchers discover drug target and genetic pathway for graft-versus-host disease

A Seattle Children's Research Institute lab has discovered a genetic pathway that can be targeted with existing drugs to prevent graft-versus-host disease (GVHD), a common and deadly complication of bone marrow transplants.

30 Nov 2015

Mallinckrodt sells CMDS business to Guerbet for $270 million

Mallinckrodt plc, a leading specialty biopharmaceutical company, announced today that it has closed the sale of its global contrast media and delivery systems (CMDS) business to Guerbet in a transaction valued at approximately $270 million.

28 Nov 2015

Prehospital combination therapy disappoints in status epilepticus

Adding levetiracetam to prehospital treatment with clonazepam does not improve control of generalised convulsive status epilepticus, shows a randomised phase III trial.

27 Nov 2015

Six-month markers predict long-term cGVHD outcomes

Researchers have identified measures early in the course of chronic graft-versus-host disease that predict long-term prognosis in haematopoietic cell transplantation recipients.

27 Nov 2015

Can-Fite BioPharma reports financial results, provides updates on drug development programs

Can-Fite BioPharma Ltd., a biotechnology company with a pipeline of proprietary small molecule drugs being developed to treat inflammatory diseases, cancer and sexual dysfunction, today reported financial results for the nine months ended September 30, 2015 and updates on its drug development programs.

27 Nov 2015

Lightpoint Medical obtains 2.4M Euro grant to carry out breast cancer clinical trial

Lightpoint Medical, an innovative medical device company specializing in imaging technologies, announced today that it has received a 2.4M Euro grant from the European Commission as part of the Horizon 2020 European Union Framework Programme for Research and Innovation, enabling the company to carry out a large-scale clinical trial in breast cancer.

26 Nov 2015

New drug combination shows promise in treating men with metastatic prostate cancer

A new drug combination may be effective in treating men with metastatic prostate cancer. Preliminary results of this new approach are encouraging and have led to an ongoing international study being conducted in 196 hospitals worldwide.

26 Nov 2015

Queen's University Belfast-led study examines potential of new technology that could save lives in ICUs

A potentially revolutionary new technology - that could saves thousands of lives in Intensive Care Units around the world - is being trialled in a UK study co-led by Queen's University Belfast.

26 Nov 2015

Takeda receives FDA approval for NINLARO (ixazomib) capsules to treat patients with multiple myeloma

Takeda Pharmaceutical Company Limited today announced that the U.S. Food and Drug Administration has approved NINLARO (ixazomib) capsules, the first and only oral proteasome inhibitor, indicated in combination with lenalidomide and dexamethasone for the treatment of patients with multiple myeloma who have received at least one prior therapy. NINLARO is a once-weekly pill.

25 Nov 2015

First seasonal influenza vaccine containing adjuvant now approved by FDA

The U.S. Food and Drug Administration today approved Fluad, the first seasonal influenza vaccine containing an adjuvant. Fluad, a trivalent vaccine produced from three influenza virus strains (two subtype A and one type B), is approved for the prevention of seasonal influenza in people 65 years of age and older.

25 Nov 2015

New collaboration aims to develop novel generation artificial pancreas

Debiotech SA, the ARTORG Center for Biomedical Engineering Research of the University of Bern - and the Division of Endocrinology, Diabetes and Clinical Nutrition of the Bern University Hospital "Inselspital" are proud to announce the start of an exclusive collaboration to develop a novel generation artificial pancreas.

24 Nov 2015

Clinical Trial News and Research

Experimental gene therapy may improve health outcomes for patients with some forms of blood disorders

EKF biomarker identifies likely development of Diabetic Nephropathy

Bacteriophage therapy: an alternative to antibiotics? An interview Professor Clokie

Synthetic Biologics announces positive results from first SYN-004 Phase 2a study for prevention of CDI, AAD

Taking estriol along with conventional medications helps RRMS patients avoid relapses

STSI launches home-based clinical trial that uses wearable sensors to identify people with AFib

Combination of antiviral medications can eradicate HCV infection in patients with advanced liver disease

UVA opens clinical trial to examine non-surgical treatment for lower urinary tract symptoms

Could statins treat muscular dystrophy? An interview with Dr. Nick Whitehead and Dr Stan Froehner

Researchers discover drug target and genetic pathway for graft-versus-host disease

Mallinckrodt sells CMDS business to Guerbet for $270 million

Prehospital combination therapy disappoints in status epilepticus

Six-month markers predict long-term cGVHD outcomes

Can-Fite BioPharma reports financial results, provides updates on drug development programs

Lightpoint Medical obtains 2.4M Euro grant to carry out breast cancer clinical trial

New drug combination shows promise in treating men with metastatic prostate cancer

Queen's University Belfast-led study examines potential of new technology that could save lives in ICUs

Takeda receives FDA approval for NINLARO (ixazomib) capsules to treat patients with multiple myeloma

First seasonal influenza vaccine containing adjuvant now approved by FDA

New collaboration aims to develop novel generation artificial pancreas

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