Immune System News and Research

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Brain tumors trap immune cells needed to fight cancer in the bone marrow, finds research

Certain brain cancers are associated with low numbers of immune system T-cells circulating in the peripheral blood. Low T-cell numbers can be a side-effect of cancer treatment. But it now appears that there is more to the story of these missing T-cells.

20 Aug 2018

Understanding How Antibodies Shape the Gut Microbiome

Dr. Keiichiro Suzuki discusses the importance of IgA in the human body, and his recent research study, which showed that IgA interacts with the gut microbiome and promotes the growth of healthy bacteria.

20 Aug 2018

Scientists identify pathways that reveal insights into mechanism of lung cancer etiology

Lung cancer is the leading cause of preventable cancer death. A disease of complex origin, lung cancer is usually considered to result from effects of smoking and from multiple genetic variants.

17 Aug 2018

Research explores relationship between personal history of infectious fever and cancer risk

Recurring patterns in patient accounts suggest the existence of an inverse relationship between personal history of infectious fever and cancer risk, and these patterns are documented throughout decades of medical literature.

17 Aug 2018

Seeking solutions to treat scleroderma

It begins with cold hands. Not just put-on-some-gloves cold. Instead, the fingers overreact to cold by turning white or blue and may become numb or tingly.

17 Aug 2018

Researchers describe promising strategy to remove melanoma's most powerful defenses

Immunotherapies use the immune system to fight cancer. But cancers like melanoma have found ways to turn off the immune system, allowing them to resist treatments and often leading to recurrence.

16 Aug 2018

Study finds role of autoimmunity in development of COPD

Autoimmunity plays a role in the development of chronic obstructive pulmonary disease (COPD), according to a study led by Georgia State University and Vanderbilt University Medical Center that analyzed human genome information stored in Vanderbilt's DNA biobank.

16 Aug 2018

Immune cell found to play important role in photosensitivity

Researchers at Hospital for Special Surgery have discovered that a type of immune cell known as Langerhans appears to play an important role in photosensitivity, an immune system reaction to sunlight that can trigger severe skin rashes.

16 Aug 2018

Researchers develop molecular matrix that delivers healing stem cells to injured elderly muscles

A car accident leaves an aging patient with severe muscle injuries that won't heal. Treatment with muscle stem cells from a donor might restore damaged tissue, but doctors are unable to deliver them effectively. A new method may help change this.

16 Aug 2018

Study uncovers mechanism that affects multiplication of dengue virus lineage

A lineage of type 1 dengue virus found in Brazil is able to prevail over another even though it multiplies less in vector mosquitoes and infected human cells.

15 Aug 2018

New discoveries show how protein droplets do more than keep cells’ interiors tidy

Inside cells, where DNA is packed tightly in the nucleus and rigid proteins keep intricate transport systems on track, some molecules have a simpler way of establishing order. They can self-organize, find one another in crowded spaces, and quickly coalesce into droplets - like oil in water.

15 Aug 2018

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

For the first time, Mount Sinai researchers have identified a way to make large numbers of immune cells that can help prevent cancer reoccurrence, according to a study published in August in Cell Reports.

15 Aug 2018

Researchers focus on uncoupling obesity from diabetes

About 422 million people around the world, including more than 30 million Americans, have diabetes. Approximately ninety percent of them have type 2 diabetes. People with this condition cannot effectively use insulin, a hormone made by the pancreas that helps the body turn blood sugar into energy.

15 Aug 2018

Scientists identify stress hormone as key factor in failure of immune system to inhibit leukemia

The human stress hormone cortisol has been identified by scientists at the University of Kent as a key factor when the immune system fails to prevent leukemia taking hold.

14 Aug 2018

Study: IgG3 antibody stops B cells from fighting pathogens in HIV patients

For the first time, scientists have shown that in certain people living with HIV, a type of antibody called immunoglobulin G3 stops the immune system's B cells from doing their normal job of fighting pathogens.

14 Aug 2018

University Hospitals Seidman Cancer Center launches new CAR-T therapy trial

University Hospitals Seidman Cancer Center launched a new clinical trial for CAR-T, joining a select group of hospitals offering the therapy and a smaller group of hospitals manufacturing the CAR-T cells.

14 Aug 2018

Duke researchers track missing T-cells in glioblastoma patients

Glioblastoma brain tumors can have an unusual effect on the body's immune system, often causing a dramatic drop in the number of circulating T-cells that help drive the body's defenses.

13 Aug 2018

Altered nitrogen metabolism may contribute to emergence of new cancer mutations

Nitrogen is a basic building block of all the body's proteins, RNA and DNA, so cancerous tumors are greedy for this element. Researchers at the Weizmann Institute of Science, in collaboration with colleagues from the National Cancer Institute and elsewhere, have now shown that in many cancers, the patient's nitrogen metabolism is altered, producing detectable changes in the body fluids and contributing to the emergence of new mutations in cancerous tissue.

13 Aug 2018

Researchers find link between common 'harmless' virus and cardiovascular damage

Researchers from Brighton and Sussex Medical School have found an unexpectedly close link between a herpes virus and the occurrence of immune cells damaging cardiovascular tissue.

13 Aug 2018

Glaucoma could be an autoimmune disorder, study suggests

Glaucoma, a disease that afflicts nearly 70 million people worldwide, is something of a mystery despite its prevalence. Little is known about the origins of the disease, which damages the retina and optic nerve and can lead to blindness.

10 Aug 2018

Immune System News and Research

Brain tumors trap immune cells needed to fight cancer in the bone marrow, finds research

Understanding How Antibodies Shape the Gut Microbiome

Scientists identify pathways that reveal insights into mechanism of lung cancer etiology

Research explores relationship between personal history of infectious fever and cancer risk

Seeking solutions to treat scleroderma

Researchers describe promising strategy to remove melanoma's most powerful defenses

Study finds role of autoimmunity in development of COPD

Immune cell found to play important role in photosensitivity

Researchers develop molecular matrix that delivers healing stem cells to injured elderly muscles

Study uncovers mechanism that affects multiplication of dengue virus lineage

New discoveries show how protein droplets do more than keep cells’ interiors tidy

Researchers identify way to grow immune cells at large scale for preventing cancer reoccurrence

Researchers focus on uncoupling obesity from diabetes

Scientists identify stress hormone as key factor in failure of immune system to inhibit leukemia

Study: IgG3 antibody stops B cells from fighting pathogens in HIV patients

University Hospitals Seidman Cancer Center launches new CAR-T therapy trial

Duke researchers track missing T-cells in glioblastoma patients

Altered nitrogen metabolism may contribute to emergence of new cancer mutations

Researchers find link between common 'harmless' virus and cardiovascular damage

Glaucoma could be an autoimmune disorder, study suggests

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