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Black-owned hospice seeks to bring greater ease in dying to Black families

This time, it didn’t take much persuading for Mary Murphy to embrace home hospice. When her mother was dying from Alzheimer’s disease in 2020, she had been reluctant until she saw what a help it was. So when her husband, Willie, neared the end of his life, she embraced hospice again.

10 Jan 2022

Comparison of COVID-19 and influenza-associated complications

Researchers compare the number, types, and risk for complications among COVID-19 and influenza patients using claims data.

9 Jan 2022

Association of obstructive sleep apnea with hospitalization due to COVID-19

Researchers report that OSA is an independent risk factor for severe COVID-19.

7 Jan 2022

New research may help better understand the causes of human diseases

New University of Gloucestershire research aims to increase our understanding of the causes of human diseases, potentially leading to the design of better treatments in the future.

7 Jan 2022

Curia unveils comprehensive mRNA solution

Curia, formerly AMRI, a leading contract research, development and manufacturing organization, today unveiled its messenger RNA solution, which includes discovery, process development and mRNA drug substance production, through large-scale lipid manufacturing, lipid nanoparticle formulation and development for full-scale sterile fill-finish services.

From Curia Global, Inc. 7 Jan 2022

In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

A novel immunotherapy strategy using in vivo generation of transient engineered chimeric antigen receptor (CAR) T cells, through the delivery of modified mRNA, can reduce fibrosis and restore cardiac function in a mouse model of heart failure, researchers report.

6 Jan 2022

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

An experimental immunotherapy can temporarily reprogram patients' immune cells to attack a specific target via only a single injection of messenger RNA (mRNA), similar to the mRNA-based COVID-19 vaccines, according to a new study from researchers in the Perelman School of Medicine at the University of Pennsylvania.

6 Jan 2022

Study reinforces the link between microglia and some cases of brain disease

Certain subtle differences in DNA sequences are known to raise the chances a person may develop Alzheimer's or Parkinson's disease.

6 Jan 2022

Model of neuromuscular junction could accelerate new treatments for neuromuscular diseases

The neuromuscular junction - where nerves and muscle fibers meet - is an essential synapse for muscle contraction and movement.

6 Jan 2022

Some heart surgery patients may be able to control postoperative pain without opioids

Many patients who undergo heart surgery may be able to safely and effectively control postoperative pain without opioids after hospital discharge, according to research published online today in The Annals of Thoracic Surgery.

6 Jan 2022

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Not too long ago the idea of taking, for instance a skin cell and transforming it into a muscle cell was unthinkable. About 10 years ago, however, revolutionary research showed that it is indeed possible to reprogram differentiated adult cells into other types fully capable of conducting new functions.

6 Jan 2022

Switching to smokeless tobacco associated with lower cardiovascular disease risk in smokers

Regular smokers are at heightened risk of developing cardiovascular disease, but crushing the butts in favor of a "smokeless" alternative like chewing tobacco, snuff or tobacco lozenges may go a long way toward bringing the danger down to a more normal level, a new UCLA-led study shows.

6 Jan 2022

New study strengthens the link between sleep-disordered breathing and gestational diabetes

Sleep-disordered breathing in early pregnancy is associated with insulin resistance or difficulty clearing glucose from the blood, suggests a small study funded by the National Institutes of Health.

6 Jan 2022

Melatonin found to inhibit SARS-CoV-2 entry into mice brains

New research recently unveiled the utility of melatonin and melatonin-derived medicines in reducing brain entry of severe acute respiratory syndrome coronavirus 2 and subsequently preventing long-term neurological consequences of coronavirus disease 2019.

6 Jan 2022

Streamlined, efficient approaches to cell culture spectrometry and analysis

As demand for the high throughput production of high quality, highly specialized and reliable cell culture products continues to rise, laboratories and manufacturers need to move away from traditional manual analysis methods in favor of advanced real-time analysis using power spectroscopic methods.

From Thermo Fisher Scientific – Pharmaceutical and Biopharmaceutical Solutions 6 Jan 2022

SARS-CoV-2 appears to persist in organs throughout the body for months

The coronavirus disease 2019 (COVID-19), caused by the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), leads to asymptomatic or mild symptoms in most cases. However, in a significant minority, it causes moderate or severe disease, with lung damage and sometimes multi-organ dysfunction, the origin of which is currently a matter of intense debate.

6 Jan 2022

Researchers set out to determine the brain and gravity’s effect on eyesight

Colonizing Mars is no longer solely the work of science fiction but a potential future option for people who desire to live among the weightless. For headline grabbers like Jeff Bezos, NASA and Elon Musk, space colonization - or space settlement, a preferred term recommended by Bill Nye - is a big goal for the 21st century.

6 Jan 2022

Neural connections of newborns with brain injuries impact childhood functional outcomes

A new UCSF study that mapped the neural connections of newborns with two different kinds of brain injuries found the maps looked very different - and were linked to significantly different developmental outcomes years later.

6 Jan 2022

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

The LIVE-AIR phase 3 clinical trial is associated with early treatment of hyperinflammatory response with the humanized monoclonal antibody lenzilumab in COVID-19 patients with decreased oxygen saturation. The study results are posted to the medRxiv* preprint server.

6 Jan 2022

Analyzing cell-free RNA could reliably predict preeclampsia

Imaging techniques such as ultrasound technologies and minimally invasive procedures are powerful tools for assessing pregnancy health and progression.

5 Jan 2022

Heart News and Research

Black-owned hospice seeks to bring greater ease in dying to Black families

Comparison of COVID-19 and influenza-associated complications

Association of obstructive sleep apnea with hospitalization due to COVID-19

New research may help better understand the causes of human diseases

Curia unveils comprehensive mRNA solution

In vivo generation of engineered CAR T cells can reduce fibrosis and restore cardiac function after heart injury

New approach with mRNA preparation reprograms T cells to attack heart fibroblasts

Study reinforces the link between microglia and some cases of brain disease

Model of neuromuscular junction could accelerate new treatments for neuromuscular diseases

Some heart surgery patients may be able to control postoperative pain without opioids

Researchers explore novel strategy to improve the reprogramming efficiency of human fibroblasts

Switching to smokeless tobacco associated with lower cardiovascular disease risk in smokers

New study strengthens the link between sleep-disordered breathing and gestational diabetes

Melatonin found to inhibit SARS-CoV-2 entry into mice brains

Streamlined, efficient approaches to cell culture spectrometry and analysis

SARS-CoV-2 appears to persist in organs throughout the body for months

Researchers set out to determine the brain and gravity’s effect on eyesight

Neural connections of newborns with brain injuries impact childhood functional outcomes

LIVE-AIR trial demonstrates efficacy of Lenzilumab for treatment of COVID patients with decreased oxygen saturation

Analyzing cell-free RNA could reliably predict preeclampsia

Bringing real-time analytics to downstream bioprocess monitoring

Designing fluidic architecture for scalable diagnostic platforms

Evaluating new approaches for rare disease genomics

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